diff --git a/home.md b/home.md index c70b047f..4f20cf0f 100644 --- a/home.md +++ b/home.md @@ -1,6 +1,16 @@ -# Objective +--- +title: ๐Ÿ’ก The Decentralized FDA +description: 80Xing medical progress by giving all patients the right to effortlessly participate in global decentralized clinical trials ๐Ÿ’Š +published: true +date: 2024-07-28T16:52:11.076Z +tags: overview +editor: markdown +dateCreated: 2023-11-24T22:24:09.275Z +--- -80X medical progress by giving all patients the right to effortlessly participate in global decentralized clinical trials ๐Ÿ’Š +# Our Modest Proposal + +80X medical progress by upgrading fda.gov and giving all patients the right to effortlessly participate in global decentralized clinical trials ๐Ÿ’Š ## Problems We Can Solve @@ -93,49 +103,41 @@ Your data helps improve treatment rankings and benefits future patients globally **By decentralizing and automating clinical research, we could reduce the cost of new treatments by 95%!** -| Cost Item | Current Cost | New Cost | Savings | -|-----------------------------------------------------------|--------------|------------|---------| -| ๐Ÿ’พ Data Management Costs$198,014 โ†’ $10,000 | $198,014 | $10,000 | 94.9% | -| โœ… Cost Per IRB Approvals$324,081 โ†’ $5,000 | $324,081 | $5,000 | 98.5% | -| ๐Ÿ“ Cost of IRB Amendments$6,347 โ†’ $0 | $6,347 | $0 | 100.0% | -| ๐Ÿ” SDV Costs$1,486,250 โ†’ $25,000 | $1,486,250 | $25,000 | 98.3% | -| ๐Ÿค Patient Recruitment Costs$805,785 โ†’ $15,000 | $805,785 | $15,000 | 98.1% | -| ๐ŸŽฏ Patient Retention Costs$76,879 โ†’ $20,000 | $76,879 | $20,000 | 74.0% | -| ๐Ÿ‘จโ€โš•๏ธ Nurse/Research Associate Costs$2,379,605 โ†’ $150,000 | $2,379,605 | $150,000 | 93.7% | -| ๐Ÿ‘ฉโ€โš•๏ธ Physician Costs$1,966,621 โ†’ $100,000 | $1,966,621 | $100,000 | 94.9% | -| ๐Ÿฅ Clinical Procedure Total$5,937,819 โ†’ $1,000,000 | $5,937,819 | $1,000,000 | 83.2% | -| ๐Ÿงช Laboratory Costs$2,325,922 โ†’ $500,000 | $2,325,922 | $500,000 | 78.5% | -| ๐Ÿข Site Recruitment Costs$849,158 โ†’ $0 | $849,158 | $0 | 100.0% | -| ๐Ÿ—๏ธ Site Retention Costs$4,461,322 โ†’ $0 | $4,461,322 | $0 | 100.0% | -| ๐Ÿ‘ฅ Administrative Staff Costs$7,229,968 โ†’ $100,000 | $7,229,968 | $100,000 | 98.6% | -| ๐Ÿ“Š Site Monitoring Costs$4,456,717 โ†’ $0 | $4,456,717 | $0 | 100.0% | -| ๐Ÿข Site Overhead$7,386,816 โ†’ $0 | $7,386,816 | $0 | 100.0% | -| ๐Ÿ“Ž All Other Costs$17,096,703 โ†’ $100,000 | $17,096,703 | $100,000 | 99.4% | -| **TOTAL SAVINGS ๐ŸŽ‰ $56,988,007 โ†’ $2,025,000** | $56,988,007 | $2,025,000 | 95.7% | +| Cost Item | Current Cost | New Cost | Savings | +|----------------------------------------------|--------------|------------|---------| +| ๐Ÿ’พ Data Management | $198,014 | $10,000 | 94.9% | +| โœ… Cost Per IRB Approvals | $324,081 | $5,000 | 98.5% | +| ๐Ÿ“ IRB Amendments | $6,347 | $0 | 100.0% | +| ๐Ÿ” SDV | $1,486,250 | $25,000 | 98.3% | +| ๐Ÿค Patient Recruitment | $805,785 | $15,000 | 98.1% | +| ๐ŸŽฏ Patient Retention | $76,879 | $20,000 | 74.0% | +| ๐Ÿ‘จโ€โš•๏ธ Nurse/Research Associate | $2,379,605 | $150,000 | 93.7% | +| ๐Ÿ‘ฉโ€โš•๏ธ Physician | $1,966,621 | $100,000 | 94.9% | +| ๐Ÿฅ Clinical Procedure Total | $5,937,819 | $1,000,000 | 83.2% | +| ๐Ÿงช Laboratory | $2,325,922 | $500,000 | 78.5% | +| ๐Ÿข Site Recruitment | $849,158 | $0 | 100.0% | +| ๐Ÿ—๏ธ Site Retention | $4,461,322 | $0 | 100.0% | +| ๐Ÿ‘ฅ Administrative Staff | $7,229,968 | $100,000 | 98.6% | +| ๐Ÿ“Š Site Monitoring | $4,456,717 | $0 | 100.0% | +| ๐Ÿข Site Overhead | $7,386,816 | $0 | 100.0% | +| ๐Ÿ“Ž All Other | $17,096,703 | $100,000 | 99.4% | +| **TOTAL SAVINGS ๐ŸŽ‰** | $56,988,007 | $2,025,000 | 95.7% | Cost analysis based on data from: [Examination of Clinical Trial Costs and Barriers for Drug Development](https://aspe.hhs.gov/reports/examination-clinical-trial-costs-barriers-drug-development-0) by the U.S. Department of Health and Human Services, Office of the Assistant Secretary for Planning and Evaluation (ASPE). -### ๐Ÿ’ก Key Benefits - -- Automated processes reduce manual labor costs -- AI-driven analysis improves efficiency and accuracy -- Decentralized approach eliminates site-related expenses -- Blockchain technology ensures data integrity +# Platform Architecture -Our cost reduction estimates are derived from the ASPE study's analysis of clinical trial costs across different therapeutic areas and phases, incorporating potential savings from electronic data capture, simplified protocols, and decentralized trial approaches. +![](https://s3.us-east-1.amazonaws.com/static.crowdsourcingcures.org/img%2Fdfda-framework-diagram.png) -# The Disease Eradication Act -[Show your support](https://www.dfda.earth/docs/disease-eradication-act) to give people suffering access to the most promising treatments +## Check Out These Great Features! ๐Ÿ‘€ -![](https://wiki.dfda.earth/right_to_trial_act_image.jpg) +See all the wonders we could enjoy with the passage of the Disease Eradication Act! -# Your Personal FDAi Agent +### Your Personal FDAi Agent Help us give everyone a free superintelligent doctor - - [video thumbnail](https://player.vimeo.com/video/930843979?badge=0&autopause=0&player_id=0&app_id=58479) ### Your Digital Twin Safe @@ -144,35 +146,21 @@ Securely store and control your health data ![](https://user-images.githubusercontent.com/2808553/180306571-ac9cc741-6f34-4059-a814-6f8a72ed8322.png) -### Clinipedia - -The Wikipedia of Clinical Research - -![](https://fdai.earth/wp-content/uploads/2024/03/clinipedia-inflammatory-pain-small.gif) - ### Outcome Labels See how treatments affect specific health outcomes ![](https://wiki.dfda.earth/assets/outcome-labels.PNG) -### Why Decentralize the FDA? - -Learn about the historical context and need for decentralization - -![](https://thinkbynumbers.org/wp-content/uploads/2021/03/news-story-headline-1-1024x563.png) - -## Automated Clinical Research - ### Automated Data Collection -Import data from wearables and apps while leveraging AI-powered collection methods for comprehensive health insights. +Import data from wearables and apps. ![](https://fdai.earth/wp-content/uploads/2024/03/import.gif) ### Automated Analysis -Advanced AI algorithms analyze your health data to identify patterns and potential root causes. +Analyze your health data to identify patterns and potential root causes of your condition. ![](https://fdai.earth/wp-content/uploads/2024/03/root-cause-analysis-4x-small.gif) @@ -182,8 +170,6 @@ Get personalized insights and recommendations based on your real-time health dat ![](https://fdai.earth/wp-content/uploads/2024/03/real-time-decision-support-notifications-personalized-app-image.png) -## Citizen Science - ### Create Your Own Studies Anyone can create a study, become a prestigious scientist, get a link, and invite all their friends to join! @@ -196,12 +182,18 @@ Studies are published in a Wikipedia for clinical research based on everyone's d ![](https://fdai.earth/wp-content/uploads/2024/03/clinipedia-landing.gif) -### Mega-Studies +### Mega-Studies on Specific Conditions Look up your condition and see how different foods, drugs and supplements tend to improve or worsen your condition. ![](https://fdai.earth/wp-content/uploads/2024/03/clinipedia-inflammatory-pain-small.gif) +# The Disease Eradication Act + +[Show your support](https://www.dfda.earth/docs/disease-eradication-act) to give people suffering access to the most promising treatments + +![](https://wiki.dfda.earth/right_to_trial_act_image.jpg) + ## Stay Up to Date! Join our newsletter to receive updates on clinical trials, research breakthroughs, and ways to get involved. @@ -212,13 +204,11 @@ We'll keep you informed about the latest developments in decentralized clinical - [dFDA](https://www.dfda.earth/) - [Studies](https://studies.dfda.earth/) -- [Digital Twin Safe](https://www.dfda.earth/safe/redirect) +- [Digital Twin Safe](https://safe.dfda.eartht) - [FDAi](https://fdai.earth/) - [Disease Eradication Act](https://www.dfda.earth/docs/disease-eradication-act) - [50/50 Health Savings Sharing Program](https://www.dfda.earth/docs/health-savings-sharing) - [Report Bug](https://github.com/decentralized-fda/decentralized-fda/issues/new?template=bug_report.yaml) - [Request Feature](https://github.com/decentralized-fda/decentralized-fda/issues/new?template=feature_request.yaml) - [GitHub](https://github.com/decentralized-fda/decentralized-fda) -- [Docs](https://www.dfda.earth/docs) -ยฉ 2023 dFDA - Accelerating discovery to minimize suffering in the universe! ๐Ÿš€