diff --git a/src/Components/Web.JS/src/Virtualize.ts b/src/Components/Web.JS/src/Virtualize.ts
index 81dbce67a508..5e21c1729490 100644
--- a/src/Components/Web.JS/src/Virtualize.ts
+++ b/src/Components/Web.JS/src/Virtualize.ts
@@ -94,16 +94,58 @@ function init(dotNetHelper: DotNet.DotNetObject, spacerBefore: HTMLElement, spac
       // scrolling glitches.
       rangeBetweenSpacers.setStartAfter(spacerBefore);
       rangeBetweenSpacers.setEndBefore(spacerAfter);
-      const spacerSeparation = rangeBetweenSpacers.getBoundingClientRect().height;
+      const rangeRect = rangeBetweenSpacers.getBoundingClientRect();
+      const spacerSeparation = rangeRect.height;
       const containerSize = entry.rootBounds?.height;
 
+      // Accumulate scale factors from all parent elements as they multiply together
+      let scaleFactor = 1.0;
+
+      // Check for CSS scale/zoom/transform properties on parent elements (including body and html)
+      let element = spacerBefore.parentElement;
+      while (element) {
+        const computedStyle = getComputedStyle(element);
+
+        // Check for zoom property (applies uniform scaling)
+        if (computedStyle.zoom && computedStyle.zoom !== 'normal' && computedStyle.zoom !== '1') {
+          scaleFactor *= parseFloat(computedStyle.zoom);
+        }
+
+        // Check for scale property (can have separate X/Y values)
+        if (computedStyle.scale && computedStyle.scale !== 'none' && computedStyle.scale !== '1') {
+          const parts = computedStyle.scale.split(' ');
+          const scaleX = parseFloat(parts[0]);
+          const scaleY = parts.length > 1 ? parseFloat(parts[1]) : scaleX;
+          scaleFactor *= scaleY; // Use vertical scale for vertical scrolling
+        }
+
+        // Check for transform property (matrix form)
+        if (computedStyle.transform && computedStyle.transform !== 'none') {
+          // A 2D transform matrix has 6 values: matrix(scaleX, skewY, skewX, scaleY, translateX, translateY)
+          const match = computedStyle.transform.match(/matrix\([^,]+,\s*[^,]+,\s*[^,]+,\s*([^,]+)/);
+          if (match) {
+            const scaleY = parseFloat(match[1]);
+            scaleFactor *= scaleY;
+          }
+        }
+        element = element.parentElement;
+      }
+
+      // Divide by scale factor to convert from physical pixels to logical pixels.
+      const unscaledSpacerSeparation = spacerSeparation / scaleFactor;
+      const unscaledContainerSize = containerSize !== null && containerSize !== undefined ? containerSize / scaleFactor : null;
+
       if (entry.target === spacerBefore) {
-        dotNetHelper.invokeMethodAsync('OnSpacerBeforeVisible', entry.intersectionRect.top - entry.boundingClientRect.top, spacerSeparation, containerSize);
+        const spacerSize = entry.intersectionRect.top - entry.boundingClientRect.top;
+        const unscaledSpacerSize = spacerSize / scaleFactor;
+        dotNetHelper.invokeMethodAsync('OnSpacerBeforeVisible', unscaledSpacerSize, unscaledSpacerSeparation, unscaledContainerSize);
       } else if (entry.target === spacerAfter && spacerAfter.offsetHeight > 0) {
         // When we first start up, both the "before" and "after" spacers will be visible, but it's only relevant to raise a
         // single event to load the initial data. To avoid raising two events, skip the one for the "after" spacer if we know
         // it's meaningless to talk about any overlap into it.
-        dotNetHelper.invokeMethodAsync('OnSpacerAfterVisible', entry.boundingClientRect.bottom - entry.intersectionRect.bottom, spacerSeparation, containerSize);
+        const spacerSize = entry.boundingClientRect.bottom - entry.intersectionRect.bottom;
+        const unscaledSpacerSize = spacerSize / scaleFactor;
+        dotNetHelper.invokeMethodAsync('OnSpacerAfterVisible', unscaledSpacerSize, unscaledSpacerSeparation, unscaledContainerSize);
       }
     });
   }
diff --git a/src/Components/test/E2ETest/Tests/VirtualizationTest.cs b/src/Components/test/E2ETest/Tests/VirtualizationTest.cs
index 4fa21ef3fe11..bb41229abc2a 100644
--- a/src/Components/test/E2ETest/Tests/VirtualizationTest.cs
+++ b/src/Components/test/E2ETest/Tests/VirtualizationTest.cs
@@ -426,6 +426,18 @@ public void CanRefreshItemsProviderResultsInPlace()
             name => Assert.Equal("Person 3", name));
     }
 
+    [Fact]
+    public void CanScrollWhenAppliedScale()
+    {
+        Browser.MountTestComponent<VirtualizationScale>();
+        var container = Browser.Exists(By.Id("virtualize"));
+
+        var people = GetPeopleNames(container);
+        Assert.True(GetPeopleNames(container).Length > 0);
+        ScrollTopToEnd(Browser, container);
+        Assert.True(GetPeopleNames(container).Length > 0);
+    }
+
     [Theory]
     [InlineData("simple-scroll-horizontal")]
     [InlineData("complex-scroll-horizontal")]
diff --git a/src/Components/test/testassets/BasicTestApp/Index.razor b/src/Components/test/testassets/BasicTestApp/Index.razor
index f9cc718f7ca1..3f5b57ed57cc 100644
--- a/src/Components/test/testassets/BasicTestApp/Index.razor
+++ b/src/Components/test/testassets/BasicTestApp/Index.razor
@@ -123,6 +123,7 @@
         <option value="BasicTestApp.VirtualizationMaxItemCount">Virtualization MaxItemCount</option>
         <option value="BasicTestApp.VirtualizationMaxItemCount_AppContext">Virtualization MaxItemCount (via AppContext)</option>
         <option value="BasicTestApp.VirtualizationTable">Virtualization HTML table</option>
+        <option value="BasicTestApp.VirtualizationScale">Virtualization with scale</option>
         <option value="BasicTestApp.VirtualizationLargeOverscan">Virtualization large overscan</option>
         <option value="BasicTestApp.HotReload.RenderOnHotReload">Render on hot reload</option>
         <option value="BasicTestApp.SectionsTest.ParentComponentWithTwoChildren">Sections test</option>
diff --git a/src/Components/test/testassets/BasicTestApp/QuickGridTest/QuickGridVirtualizeComponent.razor b/src/Components/test/testassets/BasicTestApp/QuickGridTest/QuickGridVirtualizeComponent.razor
index b875fad0eee3..f7b6e894a506 100644
--- a/src/Components/test/testassets/BasicTestApp/QuickGridTest/QuickGridVirtualizeComponent.razor
+++ b/src/Components/test/testassets/BasicTestApp/QuickGridTest/QuickGridVirtualizeComponent.razor
@@ -29,7 +29,7 @@
             Interlocked.Increment(ref ItemsProviderCallCount);
             StateHasChanged();
             return GridItemsProviderResult.From(
-                items: Enumerable.Range(1, 100).Select(i => new Person { Id = i, Name = $"Person {i}" }).ToList(),
+                items: Enumerable.Range(request.StartIndex, request.Count ?? 10).Select(i => new Person { Id = i, Name = $"Person {i}" }).ToList(),
                 totalItemCount: 100);
         };
     }
diff --git a/src/Components/test/testassets/BasicTestApp/VirtualizationScale.razor b/src/Components/test/testassets/BasicTestApp/VirtualizationScale.razor
new file mode 100644
index 000000000000..935646f76ea9
--- /dev/null
+++ b/src/Components/test/testassets/BasicTestApp/VirtualizationScale.razor
@@ -0,0 +1,33 @@
+<div id="virtualize" style="height: 200px; overflow: auto">
+    <Virtualize ItemsProvider="@itemsProvider">
+        <tr class="person"><span>@context.Name</span></tr>
+    </Virtualize>
+</div>
+
+@code {
+    internal class Person
+    {
+        public int Id { get; set; }
+        public string Name { get; set; } = string.Empty;
+    }
+
+    private ItemsProviderDelegate<Person> itemsProvider = default!;
+
+    protected override void OnInitialized()
+    {
+        itemsProvider = async request =>
+        {
+            await Task.CompletedTask;
+            return new ItemsProviderResult<Person>(
+                items: Enumerable.Range(request.StartIndex, request.Count).Select(i => new Person { Id = i, Name = $"Person {i}" }).ToList(),
+                totalItemCount: 100);
+        };
+    }
+}
+
+<style>
+    body {
+        scale: 2 0.5;
+        transform-origin: top left;
+    }
+</style>