diff --git a/easybuild/easyblocks/p/pocl.py b/easybuild/easyblocks/p/pocl.py
new file mode 100644
index 0000000000..f9ec12f3e4
--- /dev/null
+++ b/easybuild/easyblocks/p/pocl.py
@@ -0,0 +1,52 @@
+##
+# Copyright 2009-2025 Ghent University
+#
+# This file is part of EasyBuild,
+# originally created by the HPC team of Ghent University (http://ugent.be/hpc/en),
+# with support of Ghent University (http://ugent.be/hpc),
+# the Flemish Supercomputer Centre (VSC) (https://www.vscentrum.be),
+# Flemish Research Foundation (FWO) (http://www.fwo.be/en)
+# and the Department of Economy, Science and Innovation (EWI) (http://www.ewi-vlaanderen.be/en).
+#
+# https://github.com/easybuilders/easybuild
+#
+# EasyBuild is free software: you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation v2.
+#
+# EasyBuild is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+# GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with EasyBuild.  If not, see <http://www.gnu.org/licenses/>.
+##
+"""
+EasyBuild support for pocl, implemented as an easyblock
+
+@author: Petr Král (INUITS)
+"""
+from easybuild.easyblocks.generic.cmakeninja import CMakeNinja
+from easybuild.tools.run import run_shell_cmd
+
+
+class EB_pocl(CMakeNinja):
+    """Support for building pocl."""
+
+    def configure_step(self, *args, **kwargs):
+        """
+        Try to configure without `DLLC_HOST_CPU=native` but in case it fails,
+        avoid host CPU auto-detection (which may fail on recent CPUs)
+        """
+        command = ' '.join([
+                "mkdir build &&",
+                "cd build &&",
+                self.cfg['preconfigopts'],
+                "cmake -G Ninja ",
+                self.cfg['configopts'],
+                "&& cd -"])
+        res = run_shell_cmd(command, fail_on_error=False)
+        if res.exit_code != 0:
+            self.cfg.update('configopts', 'DLLC_HOST_CPU=native')
+        CMakeNinja.configure_step(self, *args, **kwargs)