diff --git a/muted-tests.yml b/muted-tests.yml
index 77ecfb22bc61d..ffd2be970c9cd 100644
--- a/muted-tests.yml
+++ b/muted-tests.yml
@@ -224,6 +224,12 @@ tests:
   - class: org.elasticsearch.discovery.ClusterDisruptionIT
     method: testAckedIndexing
     issue: https://github.com/elastic/elasticsearch/issues/117024
+  - class: org.elasticsearch.xpack.esql.qa.mixed.MixedClusterEsqlSpecIT
+    method: test {lookup-join.LookupJoinOnTimeSeriesIndex ASYNC}
+    issue: https://github.com/elastic/elasticsearch/issues/129078
+  - class: org.elasticsearch.xpack.esql.qa.mixed.MixedClusterEsqlSpecIT
+    method: test {lookup-join.LookupJoinOnTimeSeriesIndex SYNC}
+    issue: https://github.com/elastic/elasticsearch/issues/129078
 
   # Examples:
   #