diff --git a/docs-requirements.txt b/docs-requirements.txt
index e190f302a4..3e77fe4474 100644
--- a/docs-requirements.txt
+++ b/docs-requirements.txt
@@ -7,7 +7,7 @@ fastapi>=0.65.2
 pymemcache~=1.3
 
 # Required by conf
-django>=2.2
+django>=4.2.21
 
 # Required by instrumentation and exporter packages
 aio_pika~=7.2.0
diff --git a/instrumentation/opentelemetry-instrumentation-django/pyproject.toml b/instrumentation/opentelemetry-instrumentation-django/pyproject.toml
index f7cf96f5eb..f12793c2ef 100644
--- a/instrumentation/opentelemetry-instrumentation-django/pyproject.toml
+++ b/instrumentation/opentelemetry-instrumentation-django/pyproject.toml
@@ -38,7 +38,7 @@ asgi = [
   "opentelemetry-instrumentation-asgi == 0.55b0.dev",
 ]
 instruments = [
-  "django >= 1.10",
+  "django >=4.2.21",
 ]
 
 [project.entry-points.opentelemetry_instrumentor]
diff --git a/instrumentation/opentelemetry-instrumentation-django/test-requirements-0.txt b/instrumentation/opentelemetry-instrumentation-django/test-requirements-0.txt
index f2375911d3..2fe8a47723 100644
--- a/instrumentation/opentelemetry-instrumentation-django/test-requirements-0.txt
+++ b/instrumentation/opentelemetry-instrumentation-django/test-requirements-0.txt
@@ -1,6 +1,6 @@
 asgiref==3.8.1
 Deprecated==1.2.14
-Django==2.2.28
+Django==4.2.16
 iniconfig==2.0.0
 packaging==24.0
 pluggy==1.5.0
diff --git a/instrumentation/opentelemetry-instrumentation-django/test-requirements-1.txt b/instrumentation/opentelemetry-instrumentation-django/test-requirements-1.txt
index 12f934acd4..526a9b106f 100644
--- a/instrumentation/opentelemetry-instrumentation-django/test-requirements-1.txt
+++ b/instrumentation/opentelemetry-instrumentation-django/test-requirements-1.txt
@@ -1,6 +1,6 @@
 asgiref==3.8.1
 Deprecated==1.2.14
-Django==3.2.25
+Django==4.2.16
 iniconfig==2.0.0
 packaging==24.0
 pluggy==1.5.0
diff --git a/instrumentation/opentelemetry-instrumentation-django/test-requirements-2.txt b/instrumentation/opentelemetry-instrumentation-django/test-requirements-2.txt
index 6d84c3db89..bbb9bf57b6 100644
--- a/instrumentation/opentelemetry-instrumentation-django/test-requirements-2.txt
+++ b/instrumentation/opentelemetry-instrumentation-django/test-requirements-2.txt
@@ -1,7 +1,7 @@
 asgiref==3.8.1
 backports.zoneinfo==0.2.1
 Deprecated==1.2.14
-Django==4.2.17
+Django==4.2.21
 iniconfig==2.0.0
 packaging==24.0
 pluggy==1.5.0
diff --git a/instrumentation/opentelemetry-instrumentation-django/test-requirements-3.txt b/instrumentation/opentelemetry-instrumentation-django/test-requirements-3.txt
index 61ed226da4..3e60f16a15 100644
--- a/instrumentation/opentelemetry-instrumentation-django/test-requirements-3.txt
+++ b/instrumentation/opentelemetry-instrumentation-django/test-requirements-3.txt
@@ -1,6 +1,6 @@
 asgiref==3.8.1
 Deprecated==1.2.14
-Django==4.2.17
+Django==4.2.21
 iniconfig==2.0.0
 packaging==24.0
 pluggy==1.5.0
diff --git a/renovate.json5 b/renovate.json5
new file mode 100644
index 0000000000..bb1190879c
--- /dev/null
+++ b/renovate.json5
@@ -0,0 +1,8 @@
+{
+  "$schema": "https://docs.renovatebot.com/renovate-schema.json",
+  "extends": [
+    "config:best-practices",
+    "helpers:pinGitHubActionDigestsToSemver",
+    "security:only-security-updates"
+  ]
+}