diff --git a/.changeset/long-taxis-give.md b/.changeset/long-taxis-give.md
new file mode 100644
index 0000000000..1f76124616
--- /dev/null
+++ b/.changeset/long-taxis-give.md
@@ -0,0 +1,5 @@
+---
+'@emotion/cache': patch
+---
+
+Fix Issue #2917 - Update createUnsafeSelectorsAlarm to handle multi-line parsed styles
diff --git a/packages/cache/src/stylis-plugins.ts b/packages/cache/src/stylis-plugins.ts
index f007fb4254..fb5df0a817 100644
--- a/packages/cache/src/stylis-plugins.ts
+++ b/packages/cache/src/stylis-plugins.ts
@@ -217,7 +217,7 @@ export let createUnsafeSelectorsAlarm =
         // }
         // with such inputs we wouldn't have to search for the comment at all
         // TODO: consider changing this comment placement in the next major version
-        if (node.column < element.column) {
+        if (node.line === element.line && node.column < element.column) {
           if (isIgnoringComment(node)) {
             return
           }