diff --git a/src/postamble_minimal.js b/src/postamble_minimal.js
index 9472ec752e9f8..e0871e3e6ae96 100644
--- a/src/postamble_minimal.js
+++ b/src/postamble_minimal.js
@@ -182,6 +182,15 @@ var imports = {
 };
 
 #if MINIMAL_RUNTIME_STREAMING_WASM_INSTANTIATION
+#if EXPORT_ES6 && !ENVIRONMENT_MAY_BE_AUDIO_WORKLET
+var moduleUrl = new URL('{{{ TARGET_BASENAME }}}.wasm', import.meta.url);
+#elif !EXPORT_ES6 || AUDIO_WORKLET
+var moduleUrl = '{{{ TARGET_BASENAME }}}.wasm';
+#else
+var moduleUrl = ENVIRONMENT_IS_AUDIO_WORKLET ?
+  '{{{ TARGET_BASENAME }}}.wasm' :
+  new URL('{{{ TARGET_BASENAME }}}.wasm', import.meta.url);
+#endif
 // https://caniuse.com/#feat=wasm and https://developer.mozilla.org/en-US/docs/Web/JavaScript/Reference/Global_Objects/WebAssembly/instantiateStreaming
 #if MIN_SAFARI_VERSION < 150000 || ENVIRONMENT_MAY_BE_NODE
 #if ASSERTIONS && !WASM2JS
@@ -197,13 +206,13 @@ instantiatePromise =
   // Node's fetch API cannot be used for local files, so we cannot use instantiateStreaming
   && !ENVIRONMENT_IS_NODE
 #endif
-  ? WebAssembly.instantiateStreaming(fetch('{{{ TARGET_BASENAME }}}.wasm'), imports)
+  ? WebAssembly.instantiateStreaming(fetch(moduleUrl), imports)
   : WebAssembly.instantiate(Module['wasm'], imports)).then((output) => {
 #else
 #if AUDIO_WORKLET
 instantiatePromise =
 #endif
-WebAssembly.instantiateStreaming(fetch('{{{ TARGET_BASENAME }}}.wasm'), imports).then((output) => {
+WebAssembly.instantiateStreaming(fetch(moduleUrl), imports).then((output) => {
 #endif
 
 #else // Non-streaming instantiation
diff --git a/test/test_other.py b/test/test_other.py
index 1abc8a8c7d96f..409958ab9d982 100644
--- a/test/test_other.py
+++ b/test/test_other.py
@@ -1702,6 +1702,18 @@ def test_minimal_runtime_errors(self):
     expected = 'emcc: error: MINIMAL_RUNTIME is not compatible with --preload-file'
     self.assert_fail([EMCC, test_file('hello_world.c'), '-sMINIMAL_RUNTIME', '--preload-file', 'foo'], expected)
 
+  def test_minimal_runtime_esm_streaming_instantiation(self):
+    self.run_process([EMCC, '-o', 'test.mjs',
+                      '-sMINIMAL_RUNTIME',
+                      '-sMINIMAL_RUNTIME_STREAMING_WASM_INSTANTIATION',
+                      '-sEXPORT_ES6',
+                      '-sENVIRONMENT=web',
+                      test_file('hello_world.c')])
+
+    src = read_file('test.mjs')
+    # Verify that the generated code uses import.meta.url for the wasm URL
+    self.assertContained("new URL('test.wasm', import.meta.url)", src)
+
   def test_export_all_and_exported_functions(self):
     # EXPORT_ALL should not export library functions by default.
     # This means that to export library function you also need to explicitly