diff --git a/packages/react-devtools-extensions/src/main/index.js b/packages/react-devtools-extensions/src/main/index.js
index bc948d1e6d6c9..9857659e698fc 100644
--- a/packages/react-devtools-extensions/src/main/index.js
+++ b/packages/react-devtools-extensions/src/main/index.js
@@ -636,6 +636,12 @@ if (chrome.devtools.panels.setOpenResourceHandler) {
         resource.url,
         lineNumber - 1,
         columnNumber - 1,
+        maybeError => {
+          if (maybeError && maybeError.isError) {
+            // Not a resource Chrome can open. Fallback to browser default behavior.
+            window.open(resource.url);
+          }
+        },
       );
     },
   );