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Hello @crsanderford, I think the data that comes off the scanner is usually of short precision. Each vendor will have some components of how they do the quantization to maximize the signal value over the short range. Since the shorts don't usually mean anything, they are divided by the maximum value and the raw data is saved as floats, which we prefer to work with as the physics math is continuous. Then, there is another quantization step when saving to the DICOM.

So the answer is: "maybe". Probably most papers take the floating point version of the raw data, work with that, and report all their metrics using floating point data (ignoring the quantization issues of both raw data collectio…

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@crsanderford
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