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DESCRIPTION
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Package: mutscan
Title: Preprocessing and Analysis of Deep Mutational Scanning Data
Version: 1.1.0
Authors@R:
c(person(given = "Charlotte",
family = "Soneson",
role = c("aut", "cre"),
email = "charlottesoneson@gmail.com",
comment = c(ORCID = "0000-0003-3833-2169")),
person(given = "Michael",
family = "Stadler",
role = c("aut"),
email = "michael.stadler@fmi.ch",
comment = c(ORCID = "0000-0002-2269-4934")),
person(given = "Friedrich Miescher Institute for Biomedical Research",
role = "cph"))
Description: Provides functionality for processing and statistical analysis
of multiplexed assays of variant effect (MAVE) and similar data. The
package contains functions covering the full workflow from raw FASTQ
files to publication-ready visualizations. A broad range of library
designs can be processed with a single, unified interface.
Depends:
R (>= 4.5.0)
Imports:
BiocGenerics,
S4Vectors,
methods,
SummarizedExperiment,
Rcpp,
edgeR (>= 3.42.0),
dplyr,
Matrix,
limma,
tidyr,
stats,
GGally,
ggplot2,
tidyselect (>= 1.2.0),
tibble,
rlang,
grDevices,
csaw,
rmarkdown,
xfun,
DT,
ggrepel,
IRanges,
utils,
DelayedArray,
tools
Suggests:
testthat (>= 3.0.0),
BiocStyle,
knitr,
Biostrings,
pwalign,
plotly,
scattermore,
BiocManager
SystemRequirements: GNU make
biocViews: GeneticVariability, GenomicVariation, Preprocessing
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.3.2
VignetteBuilder: knitr
LinkingTo:
Rcpp
Config/testthat/edition: 3
URL: https://github.com/fmicompbio/mutscan
BugReports: https://github.com/fmicompbio/mutscan/issues