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# gnomAD Python API (Batch Script)
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# 🧬 gnomAD Python API (Batch Script)
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## :hash: What is *gnomAD* and the purpose of this script?
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[gnomAD (The Genome Aggregation Database)](http://gnomad.broadinstitute.org/) is aggregation of thousands of exomes and genomes human sequencing studies. Also, gnomAD consortium annotates the variants with allelic frequency in genomes and exomes.
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### Example Usages
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- **How to list the variants by gene name or gene id?**
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`python gnomad_python_api.py -filter_by="gene_name" -search_by="TP53" -dataset="gnomad_r2_1"`
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> Here, "**gene_id**" can also be used instead of "**gene_name**" after stating an **Ensembl Gene ID** instead of a gene name.
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- **How to list the variants by transcripts?**
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- **How to list the variants by transcript ID?**
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`python gnomad_python_api.py -filter_by="transcript_id" -search_by="ENST00000544455" -dataset="gnomad_r3"`
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- **How to list the variants by using a file containing genes/transcripts?**
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- **How to list the variants using a file containing genes/transcripts?**
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- Prepare your file that contains gene name, Ensembl gene IDs or Ensembl transcript IDs line-by-line.
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> ENSG00000169174 <br> ENSG00000171862 <br> ENSG00000170445

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