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@@ -141,4 +141,47 @@ This article was published — to our knowledge — as the first scientific rese
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- 📄 [Read the full PDF](https://gencore.bio.nyu.edu/wp-content/uploads/2021/07/reform.pdf)
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- 🖼️ [View NFT on OpenSea](https://opensea.io/item/ethereum/0x495f947276749ce646f68ac8c248420045cb7b5e/89295771465272658208657695219245348516590738176651091797615877953749424013313)
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## Selected Publications Using *ref*orm
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*ref*orm has been used in a range of peer-reviewed studies across genomics, gene regulation, and therapeutic genome editing. Below are selected examples:
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### 🧬 High-Quality Genome Assembly in Sweet Corn
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In a Nature Communications study, *ref*orm was used to integrate edited and merged sequences into a final hybrid assembly (~2.32 Gb) of the sweet corn inbred line Ia453-sh2, improving genome accuracy and reducing manual curation.
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**Hu et al., 2021**
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*Genome Assembly and Population Genomic Analysis Provide Insights into the Evolution of Modern Sweet Corn*
### 🧪 Synthetic Enhancer Analysis in Mouse Stem Cells
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A Molecular Cell paper used *ref*orm to build precise custom genome assemblies in mouse ES cells with synthetic enhancers, enabling accurate annotation of reporter insertion sites and enhancer interactions.
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**Thomas et al., 2025**
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*Enhancer Cooperativity Can Compensate for Loss of Activity over Large Genomic Distances*
In research on stem cell therapies for cystic fibrosis, *ref*orm was used to validate genome edits in patient-derived airway basal cells, supporting the development of personalized treatments.
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