diff --git a/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/index.tsx b/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/index.tsx
index 2c960db9c16b..521048fd18f4 100644
--- a/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/index.tsx
+++ b/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/index.tsx
@@ -55,6 +55,12 @@ const router = sentryCreateBrowserRouter(
         lazyChildren: () => import('./pages/AnotherLazyRoutes').then(module => module.anotherNestedRoutes),
       },
     },
+    {
+      path: '/long-running',
+      handle: {
+        lazyChildren: () => import('./pages/LongRunningLazyRoutes').then(module => module.longRunningNestedRoutes),
+      },
+    },
     {
       path: '/static',
       element: <>Hello World</>,
diff --git a/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/pages/Index.tsx b/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/pages/Index.tsx
index aefa39d63811..3053aa57b887 100644
--- a/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/pages/Index.tsx
+++ b/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/pages/Index.tsx
@@ -15,6 +15,10 @@ const Index = () => {
       <Link to="/another-lazy/sub/555/666" id="navigation-to-another-deep">
         Navigate to Another Deep Lazy Route
       </Link>
+      <br />
+      <Link to="/long-running/slow/12345" id="navigation-to-long-running">
+        Navigate to Long Running Lazy Route
+      </Link>
     </>
   );
 };
diff --git a/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/pages/LongRunningLazyRoutes.tsx b/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/pages/LongRunningLazyRoutes.tsx
new file mode 100644
index 000000000000..416fb1e162f8
--- /dev/null
+++ b/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/src/pages/LongRunningLazyRoutes.tsx
@@ -0,0 +1,49 @@
+import React, { useEffect, useState } from 'react';
+import { Link, useParams } from 'react-router-dom';
+
+// Component that simulates a long-running component load
+//  This is used to test the POP guard during long-running pageloads
+const SlowLoadingComponent = () => {
+  const { id } = useParams<{ id: string }>();
+  const [data, setData] = useState<string | null>(null);
+  const [isLoading, setIsLoading] = useState(true);
+
+  useEffect(() => {
+    // Simulate a component that takes time to initialize
+    // This extends the pageload duration to create a window where POP events might occur
+    setTimeout(() => {
+      setData(`Data loaded for ID: ${id}`);
+      setIsLoading(false);
+    }, 1000);
+  }, [id]);
+
+  if (isLoading) {
+    return <div id="loading-indicator">Loading...</div>;
+  }
+
+  return (
+    <div id="slow-loading-content">
+      <div>{data}</div>
+      <Link to="/" id="navigate-home">
+        Go Home
+      </Link>
+    </div>
+  );
+};
+
+export const longRunningNestedRoutes = [
+  {
+    path: 'slow',
+    children: [
+      {
+        path: ':id',
+        element: <SlowLoadingComponent />,
+        loader: async () => {
+          // Simulate slow data fetching in the loader
+          await new Promise(resolve => setTimeout(resolve, 2000));
+          return null;
+        },
+      },
+    ],
+  },
+];
diff --git a/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/tests/transactions.test.ts b/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/tests/transactions.test.ts
index 34e5105f8f9d..59d43c14ae95 100644
--- a/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/tests/transactions.test.ts
+++ b/dev-packages/e2e-tests/test-applications/react-router-7-lazy-routes/tests/transactions.test.ts
@@ -294,3 +294,86 @@ test('Does not send any duplicate navigation transaction names browsing between
     '/lazy/inner/:id/:anotherId',
   ]);
 });
+
+test('Does not create premature navigation transaction during long-running lazy route pageload', async ({ page }) => {
+  const navigationPromise = waitForTransaction('react-router-7-lazy-routes', async transactionEvent => {
+    return (
+      !!transactionEvent?.transaction &&
+      transactionEvent.contexts?.trace?.op === 'navigation' &&
+      transactionEvent.transaction.includes('long-running')
+    );
+  });
+
+  const pageloadPromise = waitForTransaction('react-router-7-lazy-routes', async transactionEvent => {
+    return (
+      !!transactionEvent?.transaction &&
+      transactionEvent.contexts?.trace?.op === 'pageload' &&
+      transactionEvent.transaction === '/long-running/slow/:id'
+    );
+  });
+
+  await page.goto('/long-running/slow/12345');
+
+  const pageloadEvent = await pageloadPromise;
+
+  expect(pageloadEvent.transaction).toBe('/long-running/slow/:id');
+  expect(pageloadEvent.contexts?.trace?.op).toBe('pageload');
+
+  const slowLoadingContent = page.locator('id=slow-loading-content');
+  await expect(slowLoadingContent).toBeVisible({ timeout: 5000 });
+
+  const result = await Promise.race([
+    navigationPromise.then(() => 'navigation'),
+    new Promise<'timeout'>(resolve => setTimeout(() => resolve('timeout'), 2000)),
+  ]);
+
+  // Should timeout, meaning no unwanted navigation transaction was created
+  expect(result).toBe('timeout');
+});
+
+test('Allows legitimate POP navigation (back/forward) after pageload completes', async ({ page }) => {
+  await page.goto('/');
+
+  const navigationToLongRunning = page.locator('id=navigation-to-long-running');
+  await expect(navigationToLongRunning).toBeVisible();
+
+  const firstNavigationPromise = waitForTransaction('react-router-7-lazy-routes', async transactionEvent => {
+    return (
+      !!transactionEvent?.transaction &&
+      transactionEvent.contexts?.trace?.op === 'navigation' &&
+      transactionEvent.transaction === '/long-running/slow/:id'
+    );
+  });
+
+  await navigationToLongRunning.click();
+
+  const slowLoadingContent = page.locator('id=slow-loading-content');
+  await expect(slowLoadingContent).toBeVisible({ timeout: 5000 });
+
+  const firstNavigationEvent = await firstNavigationPromise;
+
+  expect(firstNavigationEvent.transaction).toBe('/long-running/slow/:id');
+  expect(firstNavigationEvent.contexts?.trace?.op).toBe('navigation');
+
+  // Now navigate back using browser back button (POP event)
+  // This should create a navigation transaction since pageload is complete
+  const backNavigationPromise = waitForTransaction('react-router-7-lazy-routes', async transactionEvent => {
+    return (
+      !!transactionEvent?.transaction &&
+      transactionEvent.contexts?.trace?.op === 'navigation' &&
+      transactionEvent.transaction === '/'
+    );
+  });
+
+  await page.goBack();
+
+  // Verify we're back at home
+  const homeLink = page.locator('id=navigation');
+  await expect(homeLink).toBeVisible();
+
+  const backNavigationEvent = await backNavigationPromise;
+
+  // Validate that the back navigation (POP) was properly tracked
+  expect(backNavigationEvent.transaction).toBe('/');
+  expect(backNavigationEvent.contexts?.trace?.op).toBe('navigation');
+});
diff --git a/packages/react/src/reactrouter-compat-utils/instrumentation.tsx b/packages/react/src/reactrouter-compat-utils/instrumentation.tsx
index 10db32231195..f849f865cb00 100644
--- a/packages/react/src/reactrouter-compat-utils/instrumentation.tsx
+++ b/packages/react/src/reactrouter-compat-utils/instrumentation.tsx
@@ -241,6 +241,10 @@ export function createV6CompatibleWrapCreateBrowserRouter<
 
     const activeRootSpan = getActiveRootSpan();
 
+    // Track whether we've completed the initial pageload to properly distinguish
+    // between POPs that occur during pageload vs. legitimate back/forward navigation.
+    let isInitialPageloadComplete = false;
+
     // The initial load ends when `createBrowserRouter` is called.
     // This is the earliest convenient time to update the transaction name.
     // Callbacks to `router.subscribe` are not called for the initial load.
@@ -255,20 +259,25 @@ export function createV6CompatibleWrapCreateBrowserRouter<
     }
 
     router.subscribe((state: RouterState) => {
-      if (state.historyAction === 'PUSH' || state.historyAction === 'POP') {
-        // Wait for the next render if loading an unsettled route
-        if (state.navigation.state !== 'idle') {
-          requestAnimationFrame(() => {
-            handleNavigation({
-              location: state.location,
-              routes,
-              navigationType: state.historyAction,
-              version,
-              basename,
-              allRoutes: Array.from(allRoutes),
-            });
-          });
-        } else {
+      // Check if pageload span has ended to mark completion
+      if (!isInitialPageloadComplete) {
+        const currentRootSpan = getActiveRootSpan();
+        const isStillInPageload = currentRootSpan && spanToJSON(currentRootSpan).op === 'pageload';
+
+        if (!isStillInPageload) {
+          isInitialPageloadComplete = true;
+          // Don't handle this specific callback if it's a POP that marks completion
+          if (state.historyAction === 'POP') {
+            return;
+          }
+        }
+      }
+
+      const shouldHandleNavigation =
+        state.historyAction === 'PUSH' || (state.historyAction === 'POP' && isInitialPageloadComplete);
+
+      if (shouldHandleNavigation) {
+        const navigationHandler = (): void => {
           handleNavigation({
             location: state.location,
             routes,
@@ -277,6 +286,13 @@ export function createV6CompatibleWrapCreateBrowserRouter<
             basename,
             allRoutes: Array.from(allRoutes),
           });
+        };
+
+        // Wait for the next render if loading an unsettled route
+        if (state.navigation.state !== 'idle') {
+          requestAnimationFrame(navigationHandler);
+        } else {
+          navigationHandler();
         }
       }
     });
@@ -352,17 +368,47 @@ export function createV6CompatibleWrapCreateMemoryRouter<
       updatePageloadTransaction({ activeRootSpan, location, routes, basename, allRoutes: Array.from(allRoutes) });
     }
 
+    // Track whether we've completed the initial pageload to properly distinguish
+    // between POPs that occur during pageload vs. legitimate back/forward navigation.
+    let isInitialPageloadComplete = false;
+
     router.subscribe((state: RouterState) => {
+      // Check if pageload span has ended to mark completion
+      if (!isInitialPageloadComplete) {
+        const currentRootSpan = getActiveRootSpan();
+        const isStillInPageload = currentRootSpan && spanToJSON(currentRootSpan).op === 'pageload';
+
+        if (!isStillInPageload) {
+          isInitialPageloadComplete = true;
+          // Don't handle this specific callback if it's a POP that marks completion
+          if (state.historyAction === 'POP') {
+            return;
+          }
+        }
+      }
+
       const location = state.location;
-      if (state.historyAction === 'PUSH' || state.historyAction === 'POP') {
-        handleNavigation({
-          location,
-          routes,
-          navigationType: state.historyAction,
-          version,
-          basename,
-          allRoutes: Array.from(allRoutes),
-        });
+      const shouldHandleNavigation =
+        state.historyAction === 'PUSH' || (state.historyAction === 'POP' && isInitialPageloadComplete);
+
+      if (shouldHandleNavigation) {
+        const navigationHandler = (): void => {
+          handleNavigation({
+            location,
+            routes,
+            navigationType: state.historyAction,
+            version,
+            basename,
+            allRoutes: Array.from(allRoutes),
+          });
+        };
+
+        // Wait for the next render if loading an unsettled route
+        if (state.navigation.state !== 'idle') {
+          requestAnimationFrame(navigationHandler);
+        } else {
+          navigationHandler();
+        }
       }
     });