diff --git a/sentry_sdk/profiler/continuous_profiler.py b/sentry_sdk/profiler/continuous_profiler.py
index 00dd29e36c..165bd13837 100644
--- a/sentry_sdk/profiler/continuous_profiler.py
+++ b/sentry_sdk/profiler/continuous_profiler.py
@@ -75,9 +75,11 @@ def setup_continuous_profiler(options, sdk_info, capture_func):
     # type: (Dict[str, Any], SDKInfo, Callable[[Envelope], None]) -> bool
     global _scheduler
 
-    if _scheduler is not None:
+    already_initialized = _scheduler is not None
+
+    if already_initialized:
         logger.debug("[Profiling] Continuous Profiler is already setup")
-        return False
+        teardown_continuous_profiler()
 
     if is_gevent():
         # If gevent has patched the threading modules then we cannot rely on
@@ -117,11 +119,19 @@ def setup_continuous_profiler(options, sdk_info, capture_func):
         )
     )
 
-    atexit.register(teardown_continuous_profiler)
+    if not already_initialized:
+        atexit.register(teardown_continuous_profiler)
 
     return True
 
 
+def is_profile_session_sampled():
+    # type: () -> bool
+    if _scheduler is None:
+        return False
+    return _scheduler.sampled
+
+
 def try_autostart_continuous_profiler():
     # type: () -> None
 
diff --git a/tests/profiler/test_continuous_profiler.py b/tests/profiler/test_continuous_profiler.py
index 7283ec7164..e4f5cb5e25 100644
--- a/tests/profiler/test_continuous_profiler.py
+++ b/tests/profiler/test_continuous_profiler.py
@@ -8,6 +8,7 @@
 import sentry_sdk
 from sentry_sdk.consts import VERSION
 from sentry_sdk.profiler.continuous_profiler import (
+    is_profile_session_sampled,
     get_profiler_id,
     setup_continuous_profiler,
     start_profiler,
@@ -113,19 +114,25 @@ def test_continuous_profiler_valid_mode(mode, make_options, teardown_profiling):
     ],
 )
 def test_continuous_profiler_setup_twice(mode, make_options, teardown_profiling):
-    options = make_options(mode=mode)
+    assert not is_profile_session_sampled()
+
     # setting up the first time should return True to indicate success
+    options = make_options(mode=mode, profile_session_sample_rate=1.0)
     assert setup_continuous_profiler(
         options,
         mock_sdk_info,
         lambda envelope: None,
     )
-    # setting up the second time should return False to indicate no-op
-    assert not setup_continuous_profiler(
+    assert is_profile_session_sampled()
+
+    # setting up the second time should return True to indicate re-init
+    options = make_options(mode=mode, profile_session_sample_rate=0.0)
+    assert setup_continuous_profiler(
         options,
         mock_sdk_info,
         lambda envelope: None,
     )
+    assert not is_profile_session_sampled()
 
 
 def assert_single_transaction_with_profile_chunks(