In an OpenType font collection, some tables might be referenced by multiple fonts. For example, in the Noto Sans CJK font collection, all fonts refer to the same CFF2 table (and several others, but the CFF2 table is by far the largest). However, ParseTTC treats each font as an individual object, loading and parsing the same tables repeatedly. For Noto Sans CJK, this results in a 5x increase in I/O and processing time, loading the 30 MB CFF2 table five times, once per font.
I'm not sure that the ParseTTC API is a good idea in the first place (we may only ever want one font from the collection), but if it is to exist, it should at least exploit data deduplication.