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manuscript/1-Introduction.md

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+# 1 Introduction
+ 
+{type: iframe, title:1 Introduction, width:800, height:600, poster:resources/chapt_screen_images/introduction.png}
+![](https://course.civicdb.org/no_toc/introduction.html)
+ 
+
+ 

manuscript/2-Resources-for-the-Interpretation-of-Somatic-Variants.md

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+# 2 Resources for the Interpretation of Somatic Variants
+ 
+{type: iframe, title:2 Resources for the Interpretation of Somatic Variants, width:800, height:600, poster:resources/chapt_screen_images/resources-for-the-interpretation-of-somatic-variants.png}
+![](https://course.civicdb.org/no_toc/resources-for-the-interpretation-of-somatic-variants.html)
+ 
+
+ 

manuscript/3-Introduction-to-the-CIViC-knowledgebase.md

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+# 3 Introduction to the CIViC knowledgebase
+ 
+{type: iframe, title:3 Introduction to the CIViC knowledgebase, width:800, height:600, poster:resources/chapt_screen_images/introduction-to-the-civic-knowledgebase.png}
+![](https://course.civicdb.org/no_toc/introduction-to-the-civic-knowledgebase.html)
+ 
+
+ 

manuscript/4-Conclusions.md

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+# 4 Conclusions
+ 
+{type: iframe, title:4 Conclusions, width:800, height:600, poster:resources/chapt_screen_images/conclusions.png}
+![](https://course.civicdb.org/no_toc/conclusions.html)
+ 
+
+ 

manuscript/5-References.md

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+# 5 References
+ 
+{type: iframe, title:5 References, width:800, height:600, poster:resources/chapt_screen_images/references.png}
+![](https://course.civicdb.org/no_toc/references.html)
+ 
+
+ 

manuscript/About-the-Authors.md

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+# About the Authors
+ 
+{type: iframe, title:About the Authors, width:800, height:600, poster:resources/chapt_screen_images/about-the-authors.png}
+![](https://course.civicdb.org/no_toc/about-the-authors.html)
+ 
+
+ 

manuscript/About-this-Course.md

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+# About this Course
+ 
+{type: iframe, title:About this Course, width:800, height:600, poster:resources/chapt_screen_images/index.png}
+![](https://course.civicdb.org/no_toc/index.html)
+ 
+
+ 

manuscript/Book.txt

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+About-this-Course.md
+1-Introduction.md
+2-Resources-for-the-Interpretation-of-Somatic-Variants.md
+3-Introduction-to-the-CIViC-knowledgebase.md
+4-Conclusions.md
+quiz_1.md
+5-References.md
+About-the-Authors.md

manuscript/quiz_1.md

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+
+{quiz, id: civic_intro, attempts: 10}
+
+## Intro to Somatic Variant Interpretation quiz
+
+Choose the best answer.
+
+{choose-answers: 4}
+? What is an example of a cancer-specific variant database?
+
+C) oncoKB
+m) ClinVar
+m) GenBank
+o) RefSeq
+o) gnomAD
+
+{choose-answers: 4}
+? Which of the following statements are correct
+1. Somatic cancer variants occur in tumor but not normal tissue
+2. The AMP guidelines categorize variants into 4 tiers and 4 levels
+3. CIViC is both a knowledgebase and curation platform for interpreting somatic variants
+4. Precision oncology requires accurate, comprehensive and current interpretation of somatic variants
+5. ClinVar is a database of primarily cancer variants ?
+
+C) All of the examples listed except 5
+m) 1, 3, and 5
+m) 1, 2, and 3
+o) All of the examples except 1 and 5
+o) All of the examples listed
+
+{/quiz}