- give a directory with the `tumor_dna`, `tumor_rna`, and `normal_dna` - use pyyaml package? - give option for user to supply the path the location of the files - has to handle data on both google cloud (JLF) and local file structure (WashU) - also have the user supply where the data is from. e.i. washu, bostongene, cegat etc -