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Co-authored-by: Thomas B. Mooney <[email protected]>
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05-pvacview_tour.Rmd

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When selecting a transcript set in the Variant Info panel, this panel will
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show details about the neoantigen candidates the transcripts in the set code
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for and as well as details on the transcripts itself.
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for and as well as details on the transcripts themselves.
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The Peptide Candidates from Selected Transcript Set tab shows a list of
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mutant and matched wildtype peptides and their IC50 binding
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affinity to the patient HLA alleles. Only neoantigen candidate were at least
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affinity to the patient HLA alleles. Only neoantigen candidates where at least
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one peptide-MHC binding prediction falls within the `--aggregate-inclusion-threshold`
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will be shown in this table. For HLA alleles were the peptide is not
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will be shown in this table. For HLA alleles where the peptide is not
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well-binding the prediction details will show `X`. This table also shows the
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mutant position, whether or not the neoantigen candidate has any problematic
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positions, and whether or not it failed the anchor criteria. This helps in
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## Adding Comments to Variants
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When reviewing neoantigen candidates in pVACseq, users are able to add
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comments one each variant, for example, describing what additional review is
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necessary. Please note, that comments are not saved until the "Update Comment
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comments on each variant, for example, describing what additional review is
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necessary. Please note that comments are not saved until the "Update Comment
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Section" button is pressed.
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