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When selecting a transcript set in the Variant Info panel, this panel will
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show details about the neoantigen candidates the transcripts in the set code
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- for and as well as details on the transcripts itself .
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+ for and as well as details on the transcripts themselves .
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The Peptide Candidates from Selected Transcript Set tab shows a list of
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mutant and matched wildtype peptides and their IC50 binding
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- affinity to the patient HLA alleles. Only neoantigen candidate were at least
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+ affinity to the patient HLA alleles. Only neoantigen candidates where at least
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one peptide-MHC binding prediction falls within the ` --aggregate-inclusion-threshold `
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- will be shown in this table. For HLA alleles were the peptide is not
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+ will be shown in this table. For HLA alleles where the peptide is not
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well-binding the prediction details will show ` X ` . This table also shows the
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mutant position, whether or not the neoantigen candidate has any problematic
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positions, and whether or not it failed the anchor criteria. This helps in
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## Adding Comments to Variants
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When reviewing neoantigen candidates in pVACseq, users are able to add
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- comments one each variant, for example, describing what additional review is
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- necessary. Please note, that comments are not saved until the "Update Comment
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+ comments on each variant, for example, describing what additional review is
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+ necessary. Please note that comments are not saved until the "Update Comment
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Section" button is pressed.
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