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education/biomolecular-simulations-2019/Metadynamics_tutorial/index.md

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@@ -853,7 +853,7 @@ This will ensure that the ligand is properly drawn inside the binding pocket.
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2. For the subsequent flexible refinement stages, we define the binding pocket only as passive and the ligand as active.
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This ensures that the ligand can explore the binding pocket.
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In order to create those two restraint files, use the HADDOCK server tool to generate AIR restraints: [https://wenmr.science.uu.nl/haddock-restraints](https://wenmr.science.uu.nl/haddock-restraints):
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In order to create those two restraint files, use the `Generate Restraints` option from the haddock-restraints tool accessible at [https://wenmr.science.uu.nl/haddock-restraints](https://wenmr.science.uu.nl/haddock-restraints):
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<a class="prompt prompt-info">
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Selection 1: Active residues (directly involved in the interaction) -> enter here the list of residues defining the binding site:

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