diff --git a/.appveyor.yml b/.appveyor.yml
index 500c71320..e7e9c80f9 100644
--- a/.appveyor.yml
+++ b/.appveyor.yml
@@ -14,14 +14,11 @@ install:
   # Prepend Python installation and scripts (e.g. pytest) to PATH
   - set PATH=%PYTHON%;%PYTHON%\\Scripts;%PATH%
 
-  # We need to install the python-can library itself including the dependencies
-  - "python -m pip install .[test,neovi]"
+  # Install tox
+  - "pip install tox"
 
 build: off
 
 test_script:
   # run tests
-  - "pytest"
-
-  # uplad coverage reports
-  - "codecov -X gcov"
+  - "tox -e appveyor"
diff --git a/.travis.yml b/.travis.yml
index 76195ce51..3b674f371 100644
--- a/.travis.yml
+++ b/.travis.yml
@@ -21,19 +21,14 @@ env:
 
 install:
   - if [[ "$TEST_SOCKETCAN" ]]; then sudo bash test/open_vcan.sh ; fi
-  - travis_retry pip install .[test]
+  - python setup.py install
 
 script:
   - |
+    # install tox
+    pip install tox
     # Run the tests
-    python setup.py test
-    # preserve the error code
-    RETURN_CODE=$?
-    # Upload the coverage to codecov.io
-    codecov -X gcov
-    # set error code
-    (exit $RETURN_CODE);
-
+    tox -e travis
 
 jobs:
   allow_failures:
diff --git a/doc/development.rst b/doc/development.rst
index 8bad5c58e..0e3cc5c2c 100644
--- a/doc/development.rst
+++ b/doc/development.rst
@@ -22,14 +22,30 @@ Building & Installing
 
 The following assumes that the commands are executed from the root of the repository:
 
-- The project can be built and installed with ``python setup.py build`` and
-  ``python setup.py install``.
-- The unit tests can be run with ``python setup.py test``. The tests can be run with ``python2``,
-  ``python3``, ``pypy`` or ``pypy3`` to test with other python versions, if they are installed.
-  Maybe, you need to execute ``pip3 install python-can[test]`` (or only ``pip`` for Python 2),
-  if some dependencies are missing.
-- The docs can be built with ``sphinx-build doc/ doc/_build``. Appending ``-n`` to the command
-  makes Sphinx complain about more subtle problems.
+The project can be built with::
+
+    pip install wheel
+    python setup.py sdist bdist_wheel
+
+The project can be installed in editable mode with::
+
+    pip install -e .
+
+The unit tests can be run with::
+
+    pip install tox
+    tox
+
+The documentation can be built with::
+
+    pip install -r doc/doc-requirements.txt
+    python -m sphinx -an doc build
+
+The linters can be run with::
+
+    pip install -r requirements-lint.txt
+    pylint --rcfile=.pylintrc-wip can/**.py
+    black --check --verbose can
 
 
 Creating a new interface/backend
@@ -81,7 +97,7 @@ Creating a new Release
 - Update `CONTRIBUTORS.txt` with any new contributors.
 - For larger changes update ``doc/history.rst``.
 - Sanity check that documentation has stayed inline with code.
-- Create a temporary virtual environment. Run ``python setup.py install`` and ``python setup.py test``.
+- Create a temporary virtual environment. Run ``python setup.py install`` and ``tox``.
 - Create and upload the distribution: ``python setup.py sdist bdist_wheel``.
 - Sign the packages with gpg ``gpg --detach-sign -a dist/python_can-X.Y.Z-py3-none-any.whl``.
 - Upload with twine ``twine upload dist/python-can-X.Y.Z*``.
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 000000000..17d87f033
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,6 @@
+[build-system]
+requires = [
+    "setuptools >= 40.8",
+    "wheel",
+]
+build-backend = "setuptools.build_meta"
diff --git a/setup.cfg b/setup.cfg
index a0e8d5b6a..498ec14ac 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -1,25 +1,2 @@
-[aliases]
-test=pytest
-
 [metadata]
 license_file = LICENSE.txt
-
-[tool:pytest]
-addopts = -v --timeout=300 --cov=can --cov-config=setup.cfg
-
-[coverage:run]
-# we could also use branch coverage
-branch = False
-# already specified by call to pytest using --cov=can
-#source = can
-
-[coverage:report]
-# two digits after decimal point
-precision = 3
-show_missing = True
-exclude_lines =
-    # Have to re-enable the standard pragma, see https://coverage.readthedocs.io/en/coverage-4.5.1a/config.html#syntax
-    pragma: no cover
-
-    # Don't complain if non-runnable code isn't run:
-    if __name__ == .__main__.:
diff --git a/setup.py b/setup.py
index 8327b1432..6499aad8b 100644
--- a/setup.py
+++ b/setup.py
@@ -12,7 +12,6 @@
 from os.path import isfile, join
 import re
 import logging
-import sys
 from setuptools import setup, find_packages
 
 logging.basicConfig(level=logging.WARNING)
@@ -29,30 +28,9 @@
 extras_require = {
     "seeedstudio": ["pyserial>=3.0"],
     "serial": ["pyserial~=3.0"],
-    "neovi": ["python-ics>=2.12", "filelock"],
+    "neovi": ["python-ics>=2.12"],
 }
 
-tests_require = [
-    "pytest~=5.3",
-    "pytest-timeout~=1.3",
-    "pytest-cov~=2.8",
-    # coveragepy==5.0 fails with `Safety level may not be changed inside a transaction`
-    # on python 3.6 on MACOS
-    "coverage<5",
-    "codecov~=2.0",
-    "hypothesis~=4.56",
-] + extras_require["serial"]
-
-extras_require["test"] = tests_require
-
-# Check for 'pytest-runner' only if setup.py was invoked with 'test'.
-# This optimizes setup.py for cases when pytest-runner is not needed,
-# using the approach that is suggested upstream.
-#
-# See https://pypi.org/project/pytest-runner/#conditional-requirement
-needs_pytest = {"pytest", "test", "ptr"}.intersection(sys.argv)
-pytest_runner = ["pytest-runner"] if needs_pytest else []
-
 setup(
     # Description
     name="python-can",
@@ -110,7 +88,5 @@
         "mypy_extensions >= 0.4.0, < 0.5.0",
         'pywin32;platform_system=="Windows"',
     ],
-    setup_requires=pytest_runner,
     extras_require=extras_require,
-    tests_require=tests_require,
 )
diff --git a/tox.ini b/tox.ini
index 7447ccaf2..e5df520fe 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,11 +1,60 @@
 [tox]
-envlist = py36, py37
 
 [testenv]
+deps =
+    pytest~=5.3
+    pytest-timeout~=1.3
+    pytest-cov~=2.8
+    coverage<5
+    codecov~=2.0
+    hypothesis~=4.56
+    pyserial~=3.0
+
 commands =
-    pip install .[test]
     pytest
-passenv = CI
+
 recreate = True
-usedevelop = True
-sitepackages=False
+
+[testenv:travis]
+passenv =
+    CI
+    TRAVIS
+    TRAVIS_*
+    TEST_SOCKETCAN
+
+commands_post =
+    codecov -X gcov
+
+[testenv:appveyor]
+passenv =
+    CI
+    APPVEYOR
+    APPVEYOR_*
+
+extras = neovi
+
+commands_post =
+    codecov -X gcov
+
+[pytest]
+testpaths = test
+addopts = -v --timeout=300 --cov=can --cov-append --cov-report=term
+
+
+[coverage:run]
+# we could also use branch coverage
+branch = False
+
+[coverage:report]
+# two digits after decimal point
+precision = 3
+show_missing = True
+exclude_lines =
+    # Have to re-enable the standard pragma, see https://coverage.readthedocs.io/en/coverage-4.5.1a/config.html#syntax
+    pragma: no cover
+
+    # Don't complain if non-runnable code isn't run:
+    if __name__ == .__main__.:
+
+    # Don't complain if tests don't hit defensive assertion code:
+    raise NotImplementedError