diff --git a/VERSION b/VERSION
index 79a61441..59aa62c1 100644
--- a/VERSION
+++ b/VERSION
@@ -1 +1 @@
-2.4.4
+2.4.5
diff --git a/src/schema/provenance_schema.yaml b/src/schema/provenance_schema.yaml
index aeb94969..43c53dad 100644
--- a/src/schema/provenance_schema.yaml
+++ b/src/schema/provenance_schema.yaml
@@ -915,6 +915,7 @@ ENTITIES:
       sample_category:
         type: string
         indexed: true
+        immutable: true
         required_on_create: true # Only require for cerate via POST, not update via PUT
         description: "A code representing the type of specimen. Must be an organ, block, section, or suspension"
         before_property_create_validators:
@@ -954,6 +955,7 @@ ENTITIES:
       organ:
         type: string
         indexed: true
+        immutable: true
         description: "Organ code specifier, only set if sample_type == organ.  Valid values found in: [organ types](https://github.com/hubmapconsortium/search-api/blob/main/src/search-schema/data/definitions/enums/organ_types.yaml)"
       organ_other:
         type: string
@@ -974,6 +976,7 @@ ENTITIES:
       direct_ancestor:
         type: json_string # dict
         generated: true
+        immutable: true
         transient: true
         indexed: false
         on_read_trigger: get_sample_direct_ancestor