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This is the dataset associated with the publication [A common computational and neural anomaly across mouse models of autism](https://www.nature.com/articles/s41593-025-01965-8).
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Electrophysiology, behavioral and video data were collected in mice performing the [IBL task](https://pubmed.ncbi.nlm.nih.gov/34011433/).
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Animals were either wildtype, or from one of 3 different autism models:
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-B6.129P2-Fmr1tm1Cgr/J JAX Strain #003025
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-B6.129(Cg)-Cntnap2tm2Pele/J JAX Strain #028635
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-B6.129-Shank3tm2Gfng/J JAX Strain #017688
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-_B6.129P2-Fmr1tm1Cgr/J_ JAX Strain #003025
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-_B6.129(Cg)-Cntnap2tm2Pele/J_ JAX Strain #028635
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-_B6.129-Shank3tm2Gfng/J_ JAX Strain #017688
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The following data repository contains intermediate results and code to reproduce the analysis: https://osf.io/fap2s/ and https://osf.io/fap2s/wiki/home/.
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## Overview of the Data
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We have released data from 198 Neuropixel experimental sessions, with single Neuropixel recordings, referred to as probe insertions. Those were obtained with 62 genetically modified subjects performing the IBL task.
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As output of spike-sorting, there are XXX units; of which XXX are considered to be of good quality. In total, XXX brain regions were recorded in sufficient numbers for comparison with IBL’s analysises[(IBL et al. 2023)](https://doi.org/10.1101/2023.07.04.547681).
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As output of spike-sorting, there are XXX units; of which XXX are considered to be of good quality. In total, XXX brain regions were recorded in sufficient numbers for comparison with IBL’s analyses[(IBL et al. 2023)](https://doi.org/10.1101/2023.07.04.547681).
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| Model | Subject Count | Neuropixel Count |
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|----------|---------------| --- |
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| Wildtype | 15 | 51|
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| Cntnap2 | 17 | 52|
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|shank3 | 15 | 41|
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|fmr1| 15 | 54|
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|Shank3b| 15 | 41|
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|Fmr1| 15 | 54|
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## Data structure and download
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The organisation of the data follows the standard IBL data structure.
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