diff --git a/.github/workflows/sycl-aws.yml b/.github/workflows/sycl-aws.yml
index 869b734df541d..2ed860980b19a 100644
--- a/.github/workflows/sycl-aws.yml
+++ b/.github/workflows/sycl-aws.yml
@@ -15,6 +15,9 @@ on:
         description: "JSON string with array of objects with aws-type, runs-on, aws-ami, aws-spot, aws-disk, aws-timebomb, one-job properties"
         type: string
         default: '[{"runs-on":"aws_cuda-${{ github.run_id }}-${{ github.run_attempt }}","aws-ami":"ami-01cb0573cb039ab24","aws-type":["g5.2xlarge","g5.4xlarge"],"aws-disk":"/dev/sda1:64","aws-spot":"false"}]'
+      ref:
+        type: string
+        required: false
 
 jobs:
   aws:
@@ -24,6 +27,7 @@ jobs:
       - uses: actions/checkout@v4
         with:
           sparse-checkout: devops/actions/aws-ec2
+          ref: ${{ inputs.ref || github.sha }}
       - run: npm install ./devops/actions/aws-ec2
       - uses: ./devops/actions/aws-ec2
         with:
diff --git a/.github/workflows/sycl-linux-build.yml b/.github/workflows/sycl-linux-build.yml
index 0dc956dfea752..5a3abd6b899f0 100644
--- a/.github/workflows/sycl-linux-build.yml
+++ b/.github/workflows/sycl-linux-build.yml
@@ -50,6 +50,9 @@ on:
         description: 'Artifacts retention period'
         type: string
         default: 3
+      ref:
+        type: string
+        required: false
 
     outputs:
       build_conclusion:
@@ -143,6 +146,7 @@ jobs:
       with:
         sparse-checkout: |
           devops/actions
+        ref: ${{ inputs.ref || github.sha }}
     # Cleanup will be run after all actions are completed.
     - name: Register cleanup after job is finished
       uses: ./devops/actions/cleanup
diff --git a/.github/workflows/sycl-rel-nightly.yml b/.github/workflows/sycl-rel-nightly.yml
new file mode 100644
index 0000000000000..b44c90fdddcb4
--- /dev/null
+++ b/.github/workflows/sycl-rel-nightly.yml
@@ -0,0 +1,180 @@
+name: SYCL Release Branch Nightly
+
+on:
+  workflow_dispatch:
+  schedule:
+    - cron: '0 3 * * *'
+
+permissions: read-all
+
+env:
+  # NOTE: so that GitHub Actions can trigger the scheduled workflow run - the
+  # workflow file should be on the default branch. Therefore every job should
+  # checkout the release branch.
+  SYCL_REL_BRANCH: "draft-sycl-rel-6_0_0"
+
+jobs:
+  # To avoid unnecessary scheduled runs this job checks if there are new commits
+  # since the last run. More precisely, it checks if the last commit is older
+  # than 24h. That means the previous Nightly already tested this commit.
+  check_for_new_commits:
+    runs-on: ubuntu-latest
+    name: Check for new commits
+    outputs:
+      is_new_commit: ${{ steps.is_new_commit.outputs.is_new_commit }}
+    steps:
+    - uses: actions/checkout@v4
+      with:
+        ref: ${{ env.SYCL_REL_BRANCH }}
+    - run: git show --quiet | tee -a $GITHUB_STEP_SUMMARY
+
+    - id: is_new_commit
+      if: ${{ github.event_name == 'schedule' }}
+      run: |
+        if [ -z "$(git rev-list --after="24 hours" HEAD)" ]; then
+          echo "is_new_commit=false" >> $GITHUB_OUTPUT
+        fi
+
+  ubuntu2204_build:
+    needs: [check_for_new_commits]
+    if: ${{ github.repository == 'intel/llvm' && needs.check_for_new_commits.outputs.is_new_commit != 'false' }}
+    uses: ./.github/workflows/sycl-linux-build.yml
+    secrets: inherit
+    with:
+      build_cache_root: "/__w/"
+      build_artifact_suffix: v6
+      build_configure_extra_args: '--hip --cuda'
+      merge_ref: ''
+      ref: ${{ env.SYCL_REL_BRANCH }}
+
+      # We upload the build for people to download/use, override its name and
+      # prefer widespread gzip compression.
+      artifact_archive_name: sycl_linux.tar.gz
+
+  ubuntu2204_test:
+    needs: [ubuntu2204_build]
+    if: ${{ always() && !cancelled() && needs.ubuntu2204_build.outputs.build_conclusion == 'success' }}
+    strategy:
+      fail-fast: false
+      matrix:
+        include:
+          - name: AMD/HIP
+            runner: '["Linux", "amdgpu"]'
+            image: ghcr.io/intel/llvm/ubuntu2204_build:latest
+            image_options: -u 1001 --device=/dev/dri --device=/dev/kfd
+            target_devices: ext_oneapi_hip:gpu
+            tests_selector: e2e
+
+          - name: Intel L0 GPU
+            runner: '["Linux", "gen12"]'
+            image: ghcr.io/intel/llvm/ubuntu2204_intel_drivers:latest
+            image_options: -u 1001 --device=/dev/dri -v /dev/dri/by-path:/dev/dri/by-path --privileged --cap-add SYS_ADMIN
+            target_devices: level_zero:gpu
+            reset_intel_gpu: true
+            tests_selector: e2e
+            extra_lit_opts: --param gpu-intel-gen12=True
+
+          - name: Intel OCL GPU
+            runner: '["Linux", "gen12"]'
+            image: ghcr.io/intel/llvm/ubuntu2204_intel_drivers:latest
+            image_options: -u 1001 --device=/dev/dri -v /dev/dri/by-path:/dev/dri/by-path --privileged --cap-add SYS_ADMIN
+            target_devices: opencl:gpu
+            reset_intel_gpu: true
+            tests_selector: e2e
+            extra_lit_opts: --param gpu-intel-gen12=True
+
+          - name: Intel OCL CPU
+            runner: '["Linux", "gen12"]'
+            image: ghcr.io/intel/llvm/ubuntu2204_intel_drivers:latest
+            image_options: -u 1001 --privileged --cap-add SYS_ADMIN
+            target_devices: opencl:cpu
+            tests_selector: e2e
+
+          - name: SYCL-CTS on OCL CPU
+            runner: '["Linux", "gen12"]'
+            image: ghcr.io/intel/llvm/ubuntu2204_intel_drivers:latest
+            image_options: -u 1001 --device=/dev/dri --privileged --cap-add SYS_ADMIN
+            target_devices: opencl:cpu
+            tests_selector: cts
+
+          - name: SYCL-CTS on L0 gen12
+            runner: '["Linux", "gen12"]'
+            image: ghcr.io/intel/llvm/ubuntu2204_intel_drivers:latest
+            image_options: -u 1001 --device=/dev/dri --privileged --cap-add SYS_ADMIN
+            target_devices: level_zero:gpu
+            tests_selector: cts
+    uses: ./.github/workflows/sycl-linux-run-tests.yml
+    with:
+      name: ${{ matrix.name }}
+      runner: ${{ matrix.runner }}
+      image: ${{ matrix.image }}
+      image_options: ${{ matrix.image_options }}
+      target_devices: ${{ matrix.target_devices }}
+      tests_selector: ${{ matrix.tests_selector }}
+      extra_lit_opts: ${{ matrix.extra_lit_opts }}
+      reset_intel_gpu: ${{ matrix.reset_intel_gpu }}
+      ref: ${{ env.SYCL_REL_BRANCH }}
+      merge_ref: ''
+      sycl_toolchain_artifact: sycl_linux_default
+      sycl_toolchain_archive: ${{ needs.ubuntu2204_build.outputs.artifact_archive_name }}
+      sycl_toolchain_decompress_command: ${{ needs.ubuntu2204_build.outputs.artifact_decompress_command }}
+
+  build-win:
+    needs: [check_for_new_commits]
+    if: ${{ github.repository == 'intel/llvm' && needs.check_for_new_commits.outputs.is_new_commit != 'false' }}
+    uses: ./.github/workflows/sycl-windows-build.yml
+    with:
+      # We upload both Linux/Windows build via Github's "Releases"
+      # functionality, make sure Linux/Windows names follow the same pattern.
+      artifact_archive_name: sycl_windows.tar.gz
+      build_ref: ${{ env.SYCL_REL_BRANCH }}
+
+  e2e-win:
+    needs: build-win
+    # Continue if build was successful.
+    if: |
+      always()
+      && !cancelled()
+      && needs.build-win.outputs.build_conclusion == 'success'
+    uses: ./.github/workflows/sycl-windows-run-tests.yml
+    with:
+      name: Intel GEN12 Graphics with Level Zero
+      runner: '["Windows","gen12"]'
+      sycl_toolchain_archive: ${{ needs.build-win.outputs.artifact_archive_name }}
+      extra_lit_opts: --param gpu-intel-gen12=True
+      ref: ${{ env.SYCL_REL_BRANCH }}
+
+  cuda-aws-start:
+    needs: [ubuntu2204_build]
+    if: ${{ always() && !cancelled() && needs.ubuntu2204_build.outputs.build_conclusion == 'success' }}
+    uses: ./.github/workflows/sycl-aws.yml
+    secrets: inherit
+    with:
+      mode: start
+      ref: ${{ env.SYCL_REL_BRANCH }}
+
+  cuda-run-tests:
+    needs: [ubuntu2204_build, cuda-aws-start]
+    if: ${{ always() && !cancelled() && needs.ubuntu2204_build.outputs.build_conclusion == 'success' }}
+    uses: ./.github/workflows/sycl-linux-run-tests.yml
+    with:
+      name: CUDA E2E
+      runner: '["aws_cuda-${{ github.run_id }}-${{ github.run_attempt }}"]'
+      image: ghcr.io/intel/llvm/ubuntu2204_build:latest-0300ac924620a51f76c4929794637b82790f12ab
+      image_options: -u 1001 --gpus all --cap-add SYS_ADMIN --env NVIDIA_DISABLE_REQUIRE=1
+      target_devices: ext_oneapi_cuda:gpu
+      ref: ${{ env.SYCL_REL_BRANCH }}
+      merge_ref: ''
+
+      sycl_toolchain_artifact: sycl_linux_default
+      sycl_toolchain_archive: ${{ needs.ubuntu2204_build.outputs.artifact_archive_name }}
+      sycl_toolchain_decompress_command: ${{ needs.ubuntu2204_build.outputs.artifact_decompress_command }}
+
+  cuda-aws-stop:
+    needs: [cuda-aws-start, cuda-run-tests]
+    if: always()
+    uses: ./.github/workflows/sycl-aws.yml
+    secrets: inherit
+    with:
+      mode: stop
+      ref: ${{ env.SYCL_REL_BRANCH }}