(Chen1, De Pessemier1, and Myers1 et al., submitted to Nature Microbiology, 2026)
This repository contains the analysis code, processed data, and figure scripts for the manuscript:
“Multi-omics Analyses of Facial Skin in Acne Identify Distinct Microbial and Metabolic Features at Lesional and Non-lesional Sites.”
This study longitudinally profiles the skin microbiome and metabolome of 10 women with acne—alongside 10 healthy skin controls, across lesional and non-lesional sites, integrating classical microbiome and metabolomic analyses with machine learning, repeated-measures dimensionality reduction, and multi-omics approaches to uncover individualized, temporally dynamic signatures of disease severity.
