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Update the second transcript of CDKN2A
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persistence/src/main/java/org/cbioportal/genome_nexus/persistence/internal/EnsemblRepositoryImpl.java

Lines changed: 5 additions & 3 deletions
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@@ -248,10 +248,12 @@ public Set<String> findCanonicalTranscriptIdsBySource(String isoformOverrideSour
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.collect(Collectors.toSet());
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// CDKN2A is a special case where it has two canonical transcripts
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// by default the first canonical transcript ENST00000304494 is returned
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// if the isoform override source is mskcc then the second canonical transcript ENST00000361445 should be added as well
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// by default the first canonical transcript ENST00000579755 is returned
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// if the isoform override source is mskcc then the second canonical transcript ENST00000304494 should be added as well
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// ENST00000579755 is MANE plus clinical p14, ENST00000304494 is (p16 MANE). Germline transcript is MANE plus clinical.
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if ("mskcc".equalsIgnoreCase(isoformOverrideSource)) {
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canonicalTranscriptIds.add("ENST00000361570");
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canonicalTranscriptIds.add("ENST00000304494");
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}
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return canonicalTranscriptIds;
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}

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