diff --git a/flang/include/flang/Optimizer/Transforms/CUFCommon.h b/flang/include/flang/Optimizer/Builder/CUFCommon.h
similarity index 100%
rename from flang/include/flang/Optimizer/Transforms/CUFCommon.h
rename to flang/include/flang/Optimizer/Builder/CUFCommon.h
diff --git a/flang/include/flang/Optimizer/Dialect/CUF/CUFOps.td b/flang/include/flang/Optimizer/Dialect/CUF/CUFOps.td
index d06587c57d44b..9a31ffa2e9471 100644
--- a/flang/include/flang/Optimizer/Dialect/CUF/CUFOps.td
+++ b/flang/include/flang/Optimizer/Dialect/CUF/CUFOps.td
@@ -140,6 +140,17 @@ def cuf_DeallocateOp : cuf_Op<"deallocate",
   let hasVerifier = 1;
 }
 
+def cuf_SyncDescriptorOp : cuf_Op<"sync_descriptor", []> {
+  let summary =
+      "Synchronize the host and device descriptor of a Fortran pointer";
+
+  let arguments = (ins SymbolRefAttr:$globalName);
+
+  let assemblyFormat = [{
+    $globalName attr-dict
+  }];
+}
+
 def cuf_DataTransferOp : cuf_Op<"data_transfer", []> {
   let summary = "Represent a data transfer between host and device memory";
 
diff --git a/flang/include/flang/Runtime/CUDA/descriptor.h b/flang/include/flang/Runtime/CUDA/descriptor.h
index 55878aaac57fb..0ee7feca10e44 100644
--- a/flang/include/flang/Runtime/CUDA/descriptor.h
+++ b/flang/include/flang/Runtime/CUDA/descriptor.h
@@ -33,6 +33,10 @@ void *RTDECL(CUFGetDeviceAddress)(
 void RTDECL(CUFDescriptorSync)(Descriptor *dst, const Descriptor *src,
     const char *sourceFile = nullptr, int sourceLine = 0);
 
+/// Get the device address of registered with the \p hostPtr and sync them.
+void RTDECL(CUFSyncGlobalDescriptor)(
+    void *hostPtr, const char *sourceFile = nullptr, int sourceLine = 0);
+
 } // extern "C"
 
 } // namespace Fortran::runtime::cuda
diff --git a/flang/lib/Lower/Allocatable.cpp b/flang/lib/Lower/Allocatable.cpp
index fb8380ac7e8c5..4c64870675816 100644
--- a/flang/lib/Lower/Allocatable.cpp
+++ b/flang/lib/Lower/Allocatable.cpp
@@ -22,12 +22,14 @@
 #include "flang/Lower/PFTBuilder.h"
 #include "flang/Lower/Runtime.h"
 #include "flang/Lower/StatementContext.h"
+#include "flang/Optimizer/Builder/CUFCommon.h"
 #include "flang/Optimizer/Builder/FIRBuilder.h"
 #include "flang/Optimizer/Builder/Runtime/RTBuilder.h"
 #include "flang/Optimizer/Builder/Todo.h"
 #include "flang/Optimizer/Dialect/CUF/CUFOps.h"
 #include "flang/Optimizer/Dialect/FIROps.h"
 #include "flang/Optimizer/Dialect/FIROpsSupport.h"
+#include "flang/Optimizer/HLFIR/HLFIROps.h"
 #include "flang/Optimizer/Support/FatalError.h"
 #include "flang/Optimizer/Support/InternalNames.h"
 #include "flang/Parser/parse-tree.h"
@@ -1086,6 +1088,22 @@ bool Fortran::lower::isArraySectionWithoutVectorSubscript(
          !Fortran::evaluate::HasVectorSubscript(expr);
 }
 
+static void genCUFPointerSync(const mlir::Value box,
+                              fir::FirOpBuilder &builder) {
+  if (auto declareOp = box.getDefiningOp<hlfir::DeclareOp>()) {
+    if (auto addrOfOp = declareOp.getMemref().getDefiningOp<fir::AddrOfOp>()) {
+      auto mod = addrOfOp->getParentOfType<mlir::ModuleOp>();
+      if (auto globalOp =
+              mod.lookupSymbol<fir::GlobalOp>(addrOfOp.getSymbol())) {
+        if (cuf::isRegisteredDeviceGlobal(globalOp)) {
+          builder.create<cuf::SyncDescriptorOp>(box.getLoc(),
+                                                addrOfOp.getSymbol());
+        }
+      }
+    }
+  }
+}
+
 void Fortran::lower::associateMutableBox(
     Fortran::lower::AbstractConverter &converter, mlir::Location loc,
     const fir::MutableBoxValue &box, const Fortran::lower::SomeExpr &source,
@@ -1098,6 +1116,7 @@ void Fortran::lower::associateMutableBox(
   if (converter.getLoweringOptions().getLowerToHighLevelFIR()) {
     fir::ExtendedValue rhs = converter.genExprAddr(loc, source, stmtCtx);
     fir::factory::associateMutableBox(builder, loc, box, rhs, lbounds);
+    genCUFPointerSync(box.getAddr(), builder);
     return;
   }
   // The right hand side is not be evaluated into a temp. Array sections can
diff --git a/flang/lib/Optimizer/Builder/CMakeLists.txt b/flang/lib/Optimizer/Builder/CMakeLists.txt
index 05164d41a4cb5..a824d70fdb5c7 100644
--- a/flang/lib/Optimizer/Builder/CMakeLists.txt
+++ b/flang/lib/Optimizer/Builder/CMakeLists.txt
@@ -5,6 +5,7 @@ add_flang_library(FIRBuilder
   BoxValue.cpp
   Character.cpp
   Complex.cpp
+  CUFCommon.cpp
   DoLoopHelper.cpp
   FIRBuilder.cpp
   HLFIRTools.cpp
diff --git a/flang/lib/Optimizer/Transforms/CUFCommon.cpp b/flang/lib/Optimizer/Builder/CUFCommon.cpp
similarity index 97%
rename from flang/lib/Optimizer/Transforms/CUFCommon.cpp
rename to flang/lib/Optimizer/Builder/CUFCommon.cpp
index bbe33217e8f45..81a8a90ce394e 100644
--- a/flang/lib/Optimizer/Transforms/CUFCommon.cpp
+++ b/flang/lib/Optimizer/Builder/CUFCommon.cpp
@@ -6,7 +6,7 @@
 //
 //===----------------------------------------------------------------------===//
 
-#include "flang/Optimizer/Transforms/CUFCommon.h"
+#include "flang/Optimizer/Builder/CUFCommon.h"
 #include "flang/Optimizer/Dialect/CUF/CUFOps.h"
 #include "mlir/Dialect/Func/IR/FuncOps.h"
 #include "mlir/Dialect/LLVMIR/NVVMDialect.h"
diff --git a/flang/lib/Optimizer/Transforms/CMakeLists.txt b/flang/lib/Optimizer/Transforms/CMakeLists.txt
index 9eafa4ec234bd..d20d3bc4108ce 100644
--- a/flang/lib/Optimizer/Transforms/CMakeLists.txt
+++ b/flang/lib/Optimizer/Transforms/CMakeLists.txt
@@ -9,7 +9,6 @@ add_flang_library(FIRTransforms
   CompilerGeneratedNames.cpp
   ConstantArgumentGlobalisation.cpp
   ControlFlowConverter.cpp
-  CUFCommon.cpp
   CUFAddConstructor.cpp
   CUFDeviceGlobal.cpp
   CUFOpConversion.cpp
diff --git a/flang/lib/Optimizer/Transforms/CUFAddConstructor.cpp b/flang/lib/Optimizer/Transforms/CUFAddConstructor.cpp
index 9591f48c5d417..97551595db039 100644
--- a/flang/lib/Optimizer/Transforms/CUFAddConstructor.cpp
+++ b/flang/lib/Optimizer/Transforms/CUFAddConstructor.cpp
@@ -7,6 +7,7 @@
 //===----------------------------------------------------------------------===//
 
 #include "flang/Optimizer/Builder/BoxValue.h"
+#include "flang/Optimizer/Builder/CUFCommon.h"
 #include "flang/Optimizer/Builder/FIRBuilder.h"
 #include "flang/Optimizer/Builder/Runtime/RTBuilder.h"
 #include "flang/Optimizer/Builder/Todo.h"
@@ -19,7 +20,6 @@
 #include "flang/Optimizer/Dialect/FIROpsSupport.h"
 #include "flang/Optimizer/Dialect/FIRType.h"
 #include "flang/Optimizer/Support/DataLayout.h"
-#include "flang/Optimizer/Transforms/CUFCommon.h"
 #include "flang/Runtime/CUDA/registration.h"
 #include "flang/Runtime/entry-names.h"
 #include "mlir/Dialect/GPU/IR/GPUDialect.h"
diff --git a/flang/lib/Optimizer/Transforms/CUFDeviceGlobal.cpp b/flang/lib/Optimizer/Transforms/CUFDeviceGlobal.cpp
index 07cc1f3b4b51c..2e6c272fa9089 100644
--- a/flang/lib/Optimizer/Transforms/CUFDeviceGlobal.cpp
+++ b/flang/lib/Optimizer/Transforms/CUFDeviceGlobal.cpp
@@ -7,12 +7,12 @@
 //===----------------------------------------------------------------------===//
 
 #include "flang/Common/Fortran.h"
+#include "flang/Optimizer/Builder/CUFCommon.h"
 #include "flang/Optimizer/Dialect/CUF/CUFOps.h"
 #include "flang/Optimizer/Dialect/FIRDialect.h"
 #include "flang/Optimizer/Dialect/FIROps.h"
 #include "flang/Optimizer/HLFIR/HLFIROps.h"
 #include "flang/Optimizer/Support/InternalNames.h"
-#include "flang/Optimizer/Transforms/CUFCommon.h"
 #include "flang/Runtime/CUDA/common.h"
 #include "flang/Runtime/allocatable.h"
 #include "mlir/Dialect/LLVMIR/NVVMDialect.h"
diff --git a/flang/lib/Optimizer/Transforms/CUFOpConversion.cpp b/flang/lib/Optimizer/Transforms/CUFOpConversion.cpp
index de5c51556eecf..f08f9e412b885 100644
--- a/flang/lib/Optimizer/Transforms/CUFOpConversion.cpp
+++ b/flang/lib/Optimizer/Transforms/CUFOpConversion.cpp
@@ -8,6 +8,7 @@
 
 #include "flang/Optimizer/Transforms/CUFOpConversion.h"
 #include "flang/Common/Fortran.h"
+#include "flang/Optimizer/Builder/CUFCommon.h"
 #include "flang/Optimizer/Builder/Runtime/RTBuilder.h"
 #include "flang/Optimizer/CodeGen/TypeConverter.h"
 #include "flang/Optimizer/Dialect/CUF/CUFOps.h"
@@ -15,7 +16,6 @@
 #include "flang/Optimizer/Dialect/FIROps.h"
 #include "flang/Optimizer/HLFIR/HLFIROps.h"
 #include "flang/Optimizer/Support/DataLayout.h"
-#include "flang/Optimizer/Transforms/CUFCommon.h"
 #include "flang/Runtime/CUDA/allocatable.h"
 #include "flang/Runtime/CUDA/common.h"
 #include "flang/Runtime/CUDA/descriptor.h"
@@ -788,6 +788,45 @@ struct CUFLaunchOpConversion
   const mlir::SymbolTable &symTab;
 };
 
+struct CUFSyncDescriptorOpConversion
+    : public mlir::OpRewritePattern<cuf::SyncDescriptorOp> {
+  using OpRewritePattern::OpRewritePattern;
+
+  CUFSyncDescriptorOpConversion(mlir::MLIRContext *context,
+                                const mlir::SymbolTable &symTab)
+      : OpRewritePattern(context), symTab{symTab} {}
+
+  mlir::LogicalResult
+  matchAndRewrite(cuf::SyncDescriptorOp op,
+                  mlir::PatternRewriter &rewriter) const override {
+    auto mod = op->getParentOfType<mlir::ModuleOp>();
+    fir::FirOpBuilder builder(rewriter, mod);
+    mlir::Location loc = op.getLoc();
+
+    auto globalOp = mod.lookupSymbol<fir::GlobalOp>(op.getGlobalName());
+    if (!globalOp)
+      return mlir::failure();
+
+    auto hostAddr = builder.create<fir::AddrOfOp>(
+        loc, fir::ReferenceType::get(globalOp.getType()), op.getGlobalName());
+    mlir::func::FuncOp callee =
+        fir::runtime::getRuntimeFunc<mkRTKey(CUFSyncGlobalDescriptor)>(loc,
+                                                                       builder);
+    auto fTy = callee.getFunctionType();
+    mlir::Value sourceFile = fir::factory::locationToFilename(builder, loc);
+    mlir::Value sourceLine =
+        fir::factory::locationToLineNo(builder, loc, fTy.getInput(2));
+    llvm::SmallVector<mlir::Value> args{fir::runtime::createArguments(
+        builder, loc, fTy, hostAddr, sourceFile, sourceLine)};
+    builder.create<fir::CallOp>(loc, callee, args);
+    op.erase();
+    return mlir::success();
+  }
+
+private:
+  const mlir::SymbolTable &symTab;
+};
+
 class CUFOpConversion : public fir::impl::CUFOpConversionBase<CUFOpConversion> {
 public:
   void runOnOperation() override {
@@ -851,7 +890,8 @@ void cuf::populateCUFToFIRConversionPatterns(
                   CUFFreeOpConversion>(patterns.getContext());
   patterns.insert<CUFDataTransferOpConversion>(patterns.getContext(), symtab,
                                                &dl, &converter);
-  patterns.insert<CUFLaunchOpConversion>(patterns.getContext(), symtab);
+  patterns.insert<CUFLaunchOpConversion, CUFSyncDescriptorOpConversion>(
+      patterns.getContext(), symtab);
 }
 
 void cuf::populateFIRCUFConversionPatterns(const mlir::SymbolTable &symtab,
diff --git a/flang/lib/Optimizer/Transforms/SimplifyIntrinsics.cpp b/flang/lib/Optimizer/Transforms/SimplifyIntrinsics.cpp
index d3567f453fceb..fa6a7b23624e8 100644
--- a/flang/lib/Optimizer/Transforms/SimplifyIntrinsics.cpp
+++ b/flang/lib/Optimizer/Transforms/SimplifyIntrinsics.cpp
@@ -24,6 +24,7 @@
 
 #include "flang/Common/Fortran.h"
 #include "flang/Optimizer/Builder/BoxValue.h"
+#include "flang/Optimizer/Builder/CUFCommon.h"
 #include "flang/Optimizer/Builder/FIRBuilder.h"
 #include "flang/Optimizer/Builder/LowLevelIntrinsics.h"
 #include "flang/Optimizer/Builder/Todo.h"
@@ -31,7 +32,6 @@
 #include "flang/Optimizer/Dialect/FIRType.h"
 #include "flang/Optimizer/Dialect/Support/FIRContext.h"
 #include "flang/Optimizer/HLFIR/HLFIRDialect.h"
-#include "flang/Optimizer/Transforms/CUFCommon.h"
 #include "flang/Optimizer/Transforms/Passes.h"
 #include "flang/Optimizer/Transforms/Utils.h"
 #include "flang/Runtime/entry-names.h"
diff --git a/flang/runtime/CUDA/descriptor.cpp b/flang/runtime/CUDA/descriptor.cpp
index 391c47e84241d..947eeb66aa3d6 100644
--- a/flang/runtime/CUDA/descriptor.cpp
+++ b/flang/runtime/CUDA/descriptor.cpp
@@ -46,6 +46,13 @@ void RTDEF(CUFDescriptorSync)(Descriptor *dst, const Descriptor *src,
       (void *)dst, (const void *)src, count, cudaMemcpyHostToDevice));
 }
 
+void RTDEF(CUFSyncGlobalDescriptor)(
+    void *hostPtr, const char *sourceFile, int sourceLine) {
+  void *devAddr{RTNAME(CUFGetDeviceAddress)(hostPtr, sourceFile, sourceLine)};
+  RTNAME(CUFDescriptorSync)
+  ((Descriptor *)devAddr, (Descriptor *)hostPtr, sourceFile, sourceLine);
+}
+
 RT_EXT_API_GROUP_END
 }
 } // namespace Fortran::runtime::cuda
diff --git a/flang/test/Fir/CUDA/cuda-sync-desc.mlir b/flang/test/Fir/CUDA/cuda-sync-desc.mlir
new file mode 100644
index 0000000000000..20b317f34a7f2
--- /dev/null
+++ b/flang/test/Fir/CUDA/cuda-sync-desc.mlir
@@ -0,0 +1,20 @@
+// RUN: fir-opt --cuf-convert %s | FileCheck %s
+
+module attributes {dlti.dl_spec = #dlti.dl_spec<i16 = dense<16> : vector<2xi64>, i8 = dense<8> : vector<2xi64>, i32 = dense<32> : vector<2xi64>, f80 = dense<128> : vector<2xi64>, i1 = dense<8> : vector<2xi64>, !llvm.ptr = dense<64> : vector<4xi64>, i64 = dense<64> : vector<2xi64>, i128 = dense<128> : vector<2xi64>, f128 = dense<128> : vector<2xi64>, !llvm.ptr<270> = dense<32> : vector<4xi64>, f64 = dense<64> : vector<2xi64>, f16 = dense<16> : vector<2xi64>, !llvm.ptr<271> = dense<32> : vector<4xi64>, !llvm.ptr<272> = dense<64> : vector<4xi64>, "dlti.endianness" = "little", "dlti.stack_alignment" = 128 : i64>, fir.defaultkind = "a1c4d8i4l4r4", fir.kindmap = "", llvm.data_layout = "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128", llvm.ident = "flang version 20.0.0 (git@github.com:clementval/llvm-project.git f37e52237791f58438790c77edeb8de08f692987)", llvm.target_triple = "x86_64-unknown-linux-gnu"} {
+  fir.global @_QMdevptrEdev_ptr {data_attr = #cuf.cuda<device>} : !fir.box<!fir.ptr<!fir.array<?xf32>>> {
+    %0 = fir.zero_bits !fir.ptr<!fir.array<?xf32>>
+    %c0 = arith.constant 0 : index
+    %1 = fir.shape %c0 : (index) -> !fir.shape<1>
+    %2 = fir.embox %0(%1) {allocator_idx = 2 : i32} : (!fir.ptr<!fir.array<?xf32>>, !fir.shape<1>) -> !fir.box<!fir.ptr<!fir.array<?xf32>>>
+    fir.has_value %2 : !fir.box<!fir.ptr<!fir.array<?xf32>>>
+  }
+  func.func @_QQmain() {
+    cuf.sync_descriptor @_QMdevptrEdev_ptr
+    return
+  }
+}
+
+// CHECK-LABEL: func.func @_QQmain()
+// CHECK: %[[HOST_ADDR:.*]] = fir.address_of(@_QMdevptrEdev_ptr) : !fir.ref<!fir.box<!fir.ptr<!fir.array<?xf32>>>>
+// CHECK: %[[HOST_ADDR_PTR:.*]] = fir.convert %[[HOST_ADDR]] : (!fir.ref<!fir.box<!fir.ptr<!fir.array<?xf32>>>>) -> !fir.llvm_ptr<i8>
+// CHECK: fir.call @_FortranACUFSyncGlobalDescriptor(%[[HOST_ADDR_PTR]], %{{.*}}, %{{.*}}) : (!fir.llvm_ptr<i8>, !fir.ref<i8>, i32)
diff --git a/flang/test/Lower/CUDA/cuda-pointer-sync.cuf b/flang/test/Lower/CUDA/cuda-pointer-sync.cuf
new file mode 100644
index 0000000000000..e17869b2d6357
--- /dev/null
+++ b/flang/test/Lower/CUDA/cuda-pointer-sync.cuf
@@ -0,0 +1,17 @@
+! RUN: bbc -emit-hlfir -fcuda %s -o - | FileCheck %s
+
+module devptr
+  real, device, pointer, dimension(:) :: dev_ptr
+end module
+
+use devptr
+real, device, target, dimension(4) :: a_dev
+a_dev = 42.0
+dev_ptr => a_dev
+end
+
+! CHECK: fir.global @_QMdevptrEdev_ptr {data_attr = #cuf.cuda<device>} : !fir.box<!fir.ptr<!fir.array<?xf32>>>
+! CHECK-LABEL: func.func @_QQmain()
+! CHECK: fir.embox
+! CHECK: fir.store
+! CHECK: cuf.sync_descriptor @_QMdevptrEdev_ptr