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Updated the notebook
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2 files changed

+15
-6043
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2 files changed

+15
-6043
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malariagen_data/anoph/dipclust.py

Lines changed: 5 additions & 5 deletions
Original file line numberDiff line numberDiff line change
@@ -1,4 +1,4 @@
1-
from typing import Optional, Tuple
1+
from typing import Optional, Tuple, Sequence
22

33
import allel # type: ignore
44
import numpy as np
@@ -551,7 +551,7 @@ def _dipclust_concat_subplots(
551551
summary="Perform diplotype clustering, annotated with heterozygosity, gene copy number and amino acid variants.",
552552
parameters=dict(
553553
heterozygosity="Plot heterozygosity track.",
554-
snp_transcript="Plot amino acid variants for this transcript.",
554+
snp_transcripts="Plot amino acid variants for these transcripts.",
555555
cnv_region="Plot gene CNV calls for this region.",
556556
snp_filter_min_maf="Filter amino acid variants with alternate allele frequency below this threshold.",
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),
@@ -561,7 +561,7 @@ def plot_diplotype_clustering_advanced(
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region: base_params.regions,
562562
heterozygosity: bool = True,
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heterozygosity_colorscale: plotly_params.color_continuous_scale = "Greys",
564-
snp_transcript: Optional[base_params.transcript] = None,
564+
snp_transcripts: Optional[Sequence[base_params.transcript]] = None,
565565
snp_colorscale: plotly_params.color_continuous_scale = "Greys",
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snp_filter_min_maf: float = 0.05,
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snp_query: Optional[base_params.snp_query] = AA_CHANGE_QUERY,
@@ -601,7 +601,7 @@ def plot_diplotype_clustering_advanced(
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chunks: base_params.chunks = base_params.native_chunks,
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inline_array: base_params.inline_array = base_params.inline_array_default,
603603
):
604-
if cohort_size and snp_transcript:
604+
if cohort_size and snp_transcripts:
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cohort_size = None
606606
print(
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"Cohort size is not supported with amino acid heatmap. Overriding cohort size to None."
@@ -682,7 +682,7 @@ def plot_diplotype_clustering_advanced(
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figures.append(cnv_trace)
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subplot_heights.append(cnv_row_height * n_cnv_genes)
684684

685-
if snp_transcript:
685+
for snp_transcript in snp_transcripts:
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snp_trace, n_snps_transcript = self._dipclust_snp_trace(
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transcript=snp_transcript,
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sample_sets=sample_sets,

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