f [ci skip]

Author: thempel

manuscript/manuscript.tex

@@ -425,7 +425,7 @@ \subsection{MSM estimation and validation}
 \caption{Example analysis of the conformational dynamics of a pentapeptide backbone:
 (a)~The convergence behavior of the implied timescales associated with the four slowest processes.
 The solid lines refer to the maximum likelihood result while the dashed lines show the ensemble mean computed with a Bayesian sampling procedure~\cite{ben-rev-msm}.
-The black line (marking equality of timescale and lag time) with grey area indicates the timescale horizon beyond which the MSM cannot resolve processes.
+The black line (marking equality of timescale and lag time) with grey area indicates the timescale horizon below which the MSM cannot resolve processes.
 As implied timescales are well-converged at $\tau=0.5$~ns, this lag time is chosen for subsequent MSM estimation.
 (b)~Chapman-Kolmogorov test computed using an MSM estimated with lag time $\tau=0.5$~ns assuming~5 metastable states.
 Predictions from this model agree with higher lag time estimates within confidence intervals.