diff --git a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/CMakeLists.txt b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/CMakeLists.txt
index 45f860e36f9..803420fa91e 100644
--- a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/CMakeLists.txt
+++ b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/CMakeLists.txt
@@ -31,8 +31,6 @@ target_sources(mbed-mimxrt105x
         clock_config.c
         PeripheralPins.c
         pinmap.c
-        mimxrt_clock_adjustment.c
-        lpm.c
         mbed_overrides.c
 
         device/system_MIMXRT1052.c
@@ -106,6 +104,14 @@ target_sources(mbed-mimxrt105x
         ${STARTUP_FILE}
 )
 
+# Add extra sources used for deep sleep mode
+if("DEVICE_LPTICKER=1" IN_LIST MBED_TARGET_DEFINITIONS)
+    target_sources(mbed-mimxrt105x
+        INTERFACE
+            mimxrt_clock_adjustment.c
+            lpm.c)
+endif()
+
 target_link_libraries(mbed-mimxrt105x
     INTERFACE
         mbed-mcuxpresso-mcus
diff --git a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/mbed_overrides.c b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/mbed_overrides.c
index 5104506e505..d47a72e9431 100644
--- a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/mbed_overrides.c
+++ b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/mbed_overrides.c
@@ -206,7 +206,9 @@ void mbed_sdk_init()
     BOARD_Init_PMIC_STBY_REQ();
 #endif
 
+#if DEVICE_LPTICKER
     LPM_Init();
+#endif
 }
 
 void spi_setup_clock()
diff --git a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/sleep.c b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/sleep.c
index 33f14437d73..f65fe7c8373 100644
--- a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/sleep.c
+++ b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_MIMXRT105x/sleep.c
@@ -33,6 +33,7 @@ void hal_sleep(void)
     __ISB();
 }
 
+#if DEVICE_LPTICKER
 void hal_deepsleep(void)
 {
     /* Check if any of the UART's is transmitting data */
@@ -48,4 +49,9 @@ void hal_deepsleep(void)
 
     vPortPOST_SLEEP_PROCESSING(kCLOCK_ModeStop);
 }
-
+#else
+void hal_deepsleep(void)
+{
+    hal_sleep();
+}
+#endif
diff --git a/targets/targets.json5 b/targets/targets.json5
index 3e91b011372..ab4cd22181c 100644
--- a/targets/targets.json5
+++ b/targets/targets.json5
@@ -5226,8 +5226,7 @@
             "SPISLAVE",
             "TRNG",
             "WATCHDOG",
-            "USBDEVICE",
-            "LPTICKER"
+            "USBDEVICE"
         ],
         "overrides": {
             "deep-sleep-latency": 10