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Aaron Meyer
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Add binding keyword
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_bibliography/pubs.bib

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@@ -543,6 +543,7 @@ @Article{ FcgR
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month = {June},
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journal = {Cell Systems},
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doi = {10.1016/j.cels.2018.05.018},
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keywords = {binding},
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abstract = { Many immune receptors transduce activation across the plasma membrane through their
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clustering. With Fcγ receptors (FcγRs), this clustering is driven by binding to antibodies
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of differing affinities that are in turn bound to multivalent antigen. As a consequence of
@@ -737,6 +738,7 @@ @Article{ Tan2021
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url = {https://www.sciencedirect.com/science/article/pii/S002555642100122X},
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preprint = {https://biorxiv.org/cgi/content/short/2021.03.10.434776v1},
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pmid = {34637774},
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keywords = {binding},
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abstract = { Multivalent cell surface receptor binding is a ubiquitous biological phenomenon with
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functional and therapeutic significance. Predicting the amount of ligand binding for a cell
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remains an important question in computational biology as it can provide great insight into
@@ -755,15 +757,15 @@ @Article{ Jahns2023
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year = 2023,
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author = { Brian Orcutt-Jahns and Peter C. Emmel and Eli M. Snyder and Scott D. Taylor and Aaron S.
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Meyer },
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title = {Multivalent, asymmetric IL-2Fc fusions show enhanced selectivity for regulatory T
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title = {Multivalent, asymmetric IL-2--Fc fusions show enhanced selectivity for regulatory T
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cells},
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month = {October},
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day = 17,
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journal = {Science Signaling},
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doi = {10.1126/scisignal.adg0699},
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url = {https://www.science.org/stoken/author-tokens/ST-1486/full},
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preprint = {https://www.biorxiv.org/content/10.1101/2021.07.03.451002v2},
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keywords = {tensors, experimental-example, cytokines, immunology},
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keywords = {tensors, experimental-example, cytokines, immunology, binding},
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pmid = {37847758},
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abstract = { The cytokine interleukin-2 (IL-2) has the potential to treat autoimmune disease but is
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limited by its modest specificity toward immunosuppressive regulatory T (Treg) cells. IL-2
@@ -1062,6 +1064,7 @@ @Article{ Yang2023
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pmid = {37024727},
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url = {https://doi.org/10.1038/s41589-023-01313-6},
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pages = {1552-4469},
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keywords = {binding},
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abstract = {The interleukin-4 (IL-4) cytokine plays a critical role in modulating immune homeostasis.
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Although there is great interest in harnessing this cytokine as a therapeutic in natural or
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engineered formats, the clinical potential of native IL-4 is limited by its instability and
@@ -1124,6 +1127,7 @@ @Article{ Tan2023
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preprint = {https://biorxiv.org/cgi/content/short/2023.02.15.528730v1},
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doi = {10.1016/j.celrep.2023.112734},
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url = {https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00745-3},
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keywords = {binding},
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abstract = {Immunoglobulin (Ig)G antibodies coordinate immune effector responses by selectively binding
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to target antigens and then interacting with various effector cells via the Fcγ receptors.
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The Fc domain of IgG can promote or inhibit distinct effector responses across several
@@ -1384,7 +1388,7 @@ @Article{ Abraham2024
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year = {2024},
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author = {Armaan A Abraham and Zhixin Cyrillus Tan and Priyanka Shrestha and Emily R Bozich and Aaron S Meyer},
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title = {A multivalent binding model infers antibody Fc species from systems serology},
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keywords = {systems serology, antibodies, fucosylation},
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keywords = {systems serology, antibodies, fucosylation, binding},
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month = {December},
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day = 23,
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pages = {e1012663},

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