Add 42 new tools across 10 scientific domains (#91)

* Add 42 new tools across 10 scientific domains

New tool groups:
- DNA: codon optimization, primer design, Gibson/Golden Gate assembly, virtual digest
- Dose-response: 4PL curve fitting, IC50 calculation, potency comparison
- Survival analysis: Kaplan-Meier, log-rank test, Cox regression
- Drug synergy: Bliss independence, HSA, ZIP models
- CLUE L1000: signature search, perturbation, gene expression, cell lines, compounds
- L1000FWD: transcriptomic signature connectivity query
- TIMER2: immune estimation, gene correlation, survival association (via cBioPortal)
- PROTAC-DB: PROTAC search, detail retrieval, target search
- Cell Painting: IDR screen search, plate listing, well data
- Chem SA score: RDKit synthetic accessibility scoring
- OmniPath: TF-target interactions and DoRothEA regulon (2 new operations)

* bump version to 1.0.21

Author: gasvn

.gitignore

@@ -151,6 +151,9 @@ src/tooluniverse/web_tools/
 src/tooluniverse/tools_generated/FILE_ORGANIZATION_LIST.md
 temp_docs_and_tests/
 
+# Parked tools pending API keys (not ready for publishing)
+temp_tools/
+
 # Session documentation (temporary - never push)
 *_SUMMARY.md
 *_REPORT.md

pyproject.toml

@@ -4,7 +4,7 @@ build-backend = "setuptools.build_meta"
 
 [project]
 name = "tooluniverse"
-version = "1.0.20"
+version = "1.0.21"
 description = "A comprehensive collection of scientific tools for Agentic AI, offering integration with the ToolUniverse SDK and MCP Server to support advanced scientific workflows."
 authors = [
     { name = "Shanghua Gao", email = "shanghuagao@gmail.com" }