|
| 1 | +--- |
| 2 | +layout: efflux |
| 3 | +title: "Toward Phylogenetic Inference of Evolutionary Dynamics at Scale" |
| 4 | +date: 2023-07-24 |
| 5 | +permalink: "/pubs/:title" |
| 6 | +category: conference |
| 7 | +download: https://github.com/mmore500/hereditary-stratigraph-concept/releases/download/v0.3.0/hereditary-stratigraph-concept-manuscript.pdf |
| 8 | +authors: |
| 9 | + - Matthew Andres Moreno |
| 10 | + - Emily Dolson |
| 11 | + - Santiago Rodriguez-Papa |
| 12 | +venue: The 2023 Conference on Artificial Life |
| 13 | +projects: |
| 14 | + - hstrat |
| 15 | +abstract: | |
| 16 | + As digital evolution systems grow in scale and complexity, observing and interpreting their evolutionary dynamics will become increasingly challenging. |
| 17 | + Distributed and parallel computing, in particular, introduce obstacles to maintaining the high level of observability that makes digital evolution a powerful experimental tool. |
| 18 | + Phylogenetic analyses represent a promising tool for drawing inferences from digital evolution experiments at scale. |
| 19 | + Recent work has introduced promising techniques for decentralized phylogenetic inference in parallel and distributed digital evolution systems. |
| 20 | + However, foundational phylogenetic theory necessary to apply these techniques to characterize evolutionary dynamics is lacking. |
| 21 | + Here, we lay the groundwork for practical applications of distributed phylogenetic tracking in three ways: 1) we present an improved technique for reconstructing phylogenies from tunably-precise genome annotations, 2) we begin the process of identifying how the signatures of various evolutionary dynamics manifest in phylogenetic metrics, and 3) we quantify the impact of reconstruction-induced imprecision on phylogenetic metrics. |
| 22 | + We find that selection pressure, spatial structure, and ecology have distinct effects on phylogenetic metrics, although these effects are complex and not always intuitive. |
| 23 | + We also find that, while low-resolution phylogenetic reconstructions can bias some phylogenetic metrics, high-resolution reconstructions recapitulate them faithfully. |
| 24 | +bibtex: |- |
| 25 | + @inproceedings{moreno2023toward, |
| 26 | + author = {Moreno, Matthew Andres and Dolson, Emily and Rodriguez-Papa, Santiago}, |
| 27 | + title = "{Toward Phylogenetic Inference of Evolutionary Dynamics at Scale}", |
| 28 | + volume = {ALIFE 2023: The 2023 Conference on Artificial Life}, |
| 29 | + series = {ALIFE 2023: The 2023 Conference on Artificial Life}, |
| 30 | + year = {in print}, |
| 31 | + } |
| 32 | +citation: 'Matthew Andres Moreno, Emily Dolson, and Santiago Rodriguez-Papa; in print. "Toward Phylogenetic Inference of Evolutionary Dynamics at Scale." Proceedings of the ALIFE 2023: The 2023 Conference on Artificial Life. ALIFE 2023: The 2023 Conference on Artificial Life. Online.' |
| 33 | +supporting_materials: | |
| 34 | + - [data](https://osf.io/vtxwd/) [via Open Science Framework ❋](https://osf.io) |
| 35 | + - [source code](https://github.com/mmore500/hstrat-evolutionary-inference/tree/v1.0.0) [via GitHub <i class="icon-github-1"></i>](https://github.com/) |
| 36 | + - [hstrat library code](https://github.com/mmore500/hstrat/tree/v1.6.1) [via GitHub <i class="icon-github-1"></i>](https://github.com/) |
| 37 | + - [evolution conference presentation](https://youtu.be/2cRbRJSA5Qw?t=3774) [via YouTube <i class="icon-video"></i>](https://youtube.com) |
| 38 | + - [evolution conference slides](https://docs.google.com/presentation/d/1_e-_cCGmdavRN5RscQeml52IDXyQSjyvoJ6K9fLQhE8/) [via Google Slides](https://workspace.google.com/products/slides/) |
| 39 | + - [LaTeX source](https://github.com/mmore500/hstrat-evolutionary-inference/tree/239992269f9387596d4be726eb860b733e00b6ed) [via GitHub <i class="icon-github-1"></i>](https://github.com/) |
| 40 | +--- |
0 commit comments