diff --git a/.evergreen/functions.yml b/.evergreen/functions.yml
index 0fd64ce3bcd..3a450402af7 100644
--- a/.evergreen/functions.yml
+++ b/.evergreen/functions.yml
@@ -677,7 +677,7 @@ functions:
           npm i -w packages/compass-smoke-tests https://x-access-token:${generated_token}@github.com/10gen/compass-mongodb-com --engine-strict=false
 
           if [[ "$IS_WINDOWS" == "true" ]]; then
-            # TODO: windows_setup
+            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_setup --tests time-to-first-query
             npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_zip --tests auto-update-from
             npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_msi --tests auto-update-from
           fi
diff --git a/packages/compass-smoke-tests/src/installers/index.ts b/packages/compass-smoke-tests/src/installers/index.ts
index a3ac52ff4d2..31fc022b0c0 100644
--- a/packages/compass-smoke-tests/src/installers/index.ts
+++ b/packages/compass-smoke-tests/src/installers/index.ts
@@ -3,6 +3,7 @@ import { installMacDMG } from './mac-dmg';
 import { installMacZIP } from './mac-zip';
 import { installWindowsZIP } from './windows-zip';
 import { installWindowsMSI } from './windows-msi';
+import { installWindowsSetup } from './windows-setup';
 
 export function getInstaller(kind: PackageKind) {
   if (kind === 'osx_dmg') {
@@ -13,6 +14,8 @@ export function getInstaller(kind: PackageKind) {
     return installWindowsZIP;
   } else if (kind === 'windows_msi') {
     return installWindowsMSI;
+  } else if (kind === 'windows_setup') {
+    return installWindowsSetup;
   } else {
     throw new Error(`Installer for '${kind}' is not yet implemented`);
   }
diff --git a/packages/compass-smoke-tests/src/installers/windows-registry.ts b/packages/compass-smoke-tests/src/installers/windows-registry.ts
new file mode 100644
index 00000000000..452d3185247
--- /dev/null
+++ b/packages/compass-smoke-tests/src/installers/windows-registry.ts
@@ -0,0 +1,53 @@
+import cp from 'node:child_process';
+
+type RegistryEntry = {
+  key: string;
+  type: string;
+  value: string;
+};
+
+function isRegistryEntry(value: unknown): value is RegistryEntry {
+  return (
+    typeof value === 'object' &&
+    value !== null &&
+    'key' in value &&
+    typeof value.key === 'string' &&
+    'type' in value &&
+    typeof value.type === 'string' &&
+    'value' in value &&
+    typeof value.value === 'string'
+  );
+}
+
+/**
+ * Parse the putput of a "reg query" call.
+ */
+function parseQueryRegistryOutput(output: string): RegistryEntry[] {
+  const result = output.matchAll(
+    /^\s*(?<key>\w+) +(?<type>\w+) *(?<value>.*)$/gm
+  );
+  return [...result].map(({ groups }) => groups).filter(isRegistryEntry);
+}
+
+/**
+ * Query the Windows registry by key.
+ */
+export function query(key: string) {
+  const result = cp.spawnSync('reg', ['query', key], { encoding: 'utf8' });
+  if (result.status === 0) {
+    const entries = parseQueryRegistryOutput(result.stdout);
+    return Object.fromEntries(entries.map(({ key, value }) => [key, value]));
+  } else if (
+    result.status === 1 &&
+    result.stderr.trim() ===
+      'ERROR: The system was unable to find the specified registry key or value.'
+  ) {
+    return null;
+  } else {
+    throw Error(
+      `Expected either an entry or status code 1, got status ${
+        result.status ?? '?'
+      }: ${result.stderr}`
+    );
+  }
+}
diff --git a/packages/compass-smoke-tests/src/installers/windows-setup.ts b/packages/compass-smoke-tests/src/installers/windows-setup.ts
new file mode 100644
index 00000000000..fd6e4ec4fa3
--- /dev/null
+++ b/packages/compass-smoke-tests/src/installers/windows-setup.ts
@@ -0,0 +1,83 @@
+import path from 'node:path';
+import assert from 'node:assert/strict';
+import fs from 'node:fs';
+import cp from 'node:child_process';
+
+import type { InstalledAppInfo, InstallablePackage } from './types';
+import { execute } from '../execute';
+import * as windowsRegistry from './windows-registry';
+
+type UninstallOptions = {
+  /**
+   * Expect the app to already be uninstalled, warn if that's not the case.
+   */
+  expectMissing?: boolean;
+};
+
+/**
+ * Install using the Windows installer.
+ */
+export function installWindowsSetup({
+  appName,
+  filepath,
+}: InstallablePackage): InstalledAppInfo {
+  function queryRegistry() {
+    return windowsRegistry.query(
+      `HKEY_CURRENT_USER\\SOFTWARE\\Microsoft\\Windows\\CurrentVersion\\Uninstall\\${appName}`
+    );
+  }
+
+  function uninstall({ expectMissing = false }: UninstallOptions = {}) {
+    const entry = queryRegistry();
+    if (entry) {
+      const {
+        InstallLocation: installLocation,
+        UninstallString: uninstallCommand,
+      } = entry;
+      assert(
+        typeof installLocation === 'string',
+        'Expected an entry in the registry with the install location'
+      );
+      assert(
+        typeof uninstallCommand === 'string',
+        'Expected an entry in the registry with the uninstall command'
+      );
+      if (expectMissing) {
+        console.warn(
+          'Found an existing registry entry (likely from a previous run)'
+        );
+      }
+      assert(
+        typeof uninstallCommand === 'string',
+        'Expected an UninstallString in the registry entry'
+      );
+      console.log(`Running command to uninstall: ${uninstallCommand}`);
+      cp.execSync(uninstallCommand, { stdio: 'inherit' });
+      // Removing the any remaining files manually
+      fs.rmSync(installLocation, { recursive: true, force: true });
+    }
+  }
+
+  uninstall({ expectMissing: true });
+
+  // Run the installer
+  console.warn(
+    "Installing globally, since we haven't discovered a way to specify an install path"
+  );
+  execute(filepath, []);
+
+  const entry = queryRegistry();
+  assert(entry !== null, 'Expected an entry in the registry after installing');
+  const { InstallLocation: appPath } = entry;
+  assert(
+    typeof appPath === 'string',
+    'Expected an entry in the registry with the install location'
+  );
+  const appExecutablePath = path.resolve(appPath, `${appName}.exe`);
+  execute(appExecutablePath, ['--version']);
+
+  return {
+    appPath,
+    uninstall,
+  };
+}