diff --git a/pymongo/asynchronous/collection.py b/pymongo/asynchronous/collection.py
index a0b727dc7a..1ec74aad02 100644
--- a/pymongo/asynchronous/collection.py
+++ b/pymongo/asynchronous/collection.py
@@ -231,7 +231,8 @@ def __init__(
         from pymongo.asynchronous.database import AsyncDatabase
 
         if not isinstance(database, AsyncDatabase):
-            if not any(cls.__name__ == "AsyncDatabase" for cls in database.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(cls.__name__ == "AsyncDatabase" for cls in type(database).__mro__):
                 raise TypeError(f"AsyncDatabase required but given {type(database).__name__}")
 
         if not name or ".." in name:
diff --git a/pymongo/asynchronous/database.py b/pymongo/asynchronous/database.py
index fb042972be..06c0eca2c1 100644
--- a/pymongo/asynchronous/database.py
+++ b/pymongo/asynchronous/database.py
@@ -125,7 +125,8 @@ def __init__(
             raise TypeError("name must be an instance of str")
 
         if not isinstance(client, AsyncMongoClient):
-            if not any(cls.__name__ == "AsyncMongoClient" for cls in client.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(cls.__name__ == "AsyncMongoClient" for cls in type(client).__mro__):
                 raise TypeError(f"AsyncMongoClient required but given {type(client).__name__}")
 
         if name != "$external":
diff --git a/pymongo/asynchronous/encryption.py b/pymongo/asynchronous/encryption.py
index b03af1b8a1..9b00c13e10 100644
--- a/pymongo/asynchronous/encryption.py
+++ b/pymongo/asynchronous/encryption.py
@@ -597,7 +597,10 @@ def __init__(
             raise TypeError("codec_options must be an instance of bson.codec_options.CodecOptions")
 
         if not isinstance(key_vault_client, AsyncMongoClient):
-            if not any(cls.__name__ == "AsyncMongoClient" for cls in key_vault_client.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(
+                cls.__name__ == "AsyncMongoClient" for cls in type(key_vault_client).__mro__
+            ):
                 raise TypeError(
                     f"AsyncMongoClient required but given {type(key_vault_client).__name__}"
                 )
@@ -688,7 +691,8 @@ async def create_encrypted_collection(
 
         """
         if not isinstance(database, AsyncDatabase):
-            if not any(cls.__name__ == "AsyncDatabase" for cls in database.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(cls.__name__ == "AsyncDatabase" for cls in type(database).__mro__):
                 raise TypeError(f"AsyncDatabase required but given {type(database).__name__}")
 
         encrypted_fields = deepcopy(encrypted_fields)
diff --git a/pymongo/asynchronous/mongo_client.py b/pymongo/asynchronous/mongo_client.py
index 20cc65d9d7..9dba97d12a 100644
--- a/pymongo/asynchronous/mongo_client.py
+++ b/pymongo/asynchronous/mongo_client.py
@@ -2446,7 +2446,8 @@ def __init__(
         self, client: AsyncMongoClient, server: Server, session: Optional[AsyncClientSession]
     ):
         if not isinstance(client, AsyncMongoClient):
-            if not any(cls.__name__ == "AsyncMongoClient" for cls in client.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(cls.__name__ == "AsyncMongoClient" for cls in type(client).__mro__):
                 raise TypeError(f"AsyncMongoClient required but given {type(client).__name__}")
 
         self.client = client
diff --git a/pymongo/synchronous/collection.py b/pymongo/synchronous/collection.py
index ff02c65af5..7a41aef31f 100644
--- a/pymongo/synchronous/collection.py
+++ b/pymongo/synchronous/collection.py
@@ -234,7 +234,8 @@ def __init__(
         from pymongo.synchronous.database import Database
 
         if not isinstance(database, Database):
-            if not any(cls.__name__ == "Database" for cls in database.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(cls.__name__ == "Database" for cls in type(database).__mro__):
                 raise TypeError(f"Database required but given {type(database).__name__}")
 
         if not name or ".." in name:
diff --git a/pymongo/synchronous/database.py b/pymongo/synchronous/database.py
index 5f499fff61..c57a59e09a 100644
--- a/pymongo/synchronous/database.py
+++ b/pymongo/synchronous/database.py
@@ -125,7 +125,8 @@ def __init__(
             raise TypeError("name must be an instance of str")
 
         if not isinstance(client, MongoClient):
-            if not any(cls.__name__ == "MongoClient" for cls in client.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(cls.__name__ == "MongoClient" for cls in type(client).__mro__):
                 raise TypeError(f"MongoClient required but given {type(client).__name__}")
 
         if name != "$external":
diff --git a/pymongo/synchronous/encryption.py b/pymongo/synchronous/encryption.py
index 8c6411feb9..efef6df9e8 100644
--- a/pymongo/synchronous/encryption.py
+++ b/pymongo/synchronous/encryption.py
@@ -595,7 +595,8 @@ def __init__(
             raise TypeError("codec_options must be an instance of bson.codec_options.CodecOptions")
 
         if not isinstance(key_vault_client, MongoClient):
-            if not any(cls.__name__ == "MongoClient" for cls in key_vault_client.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(cls.__name__ == "MongoClient" for cls in type(key_vault_client).__mro__):
                 raise TypeError(f"MongoClient required but given {type(key_vault_client).__name__}")
 
         self._kms_providers = kms_providers
@@ -684,7 +685,8 @@ def create_encrypted_collection(
 
         """
         if not isinstance(database, Database):
-            if not any(cls.__name__ == "Database" for cls in database.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(cls.__name__ == "Database" for cls in type(database).__mro__):
                 raise TypeError(f"Database required but given {type(database).__name__}")
 
         encrypted_fields = deepcopy(encrypted_fields)
diff --git a/pymongo/synchronous/mongo_client.py b/pymongo/synchronous/mongo_client.py
index ac697405d1..21fa57b5d8 100644
--- a/pymongo/synchronous/mongo_client.py
+++ b/pymongo/synchronous/mongo_client.py
@@ -2434,7 +2434,8 @@ class _MongoClientErrorHandler:
 
     def __init__(self, client: MongoClient, server: Server, session: Optional[ClientSession]):
         if not isinstance(client, MongoClient):
-            if not any(cls.__name__ == "MongoClient" for cls in client.__mro__):
+            # This is for compatibility with mocked and subclassed types, such as in Motor.
+            if not any(cls.__name__ == "MongoClient" for cls in type(client).__mro__):
                 raise TypeError(f"MongoClient required but given {type(client).__name__}")
 
         self.client = client