diff --git a/.evergreen/config.yml b/.evergreen/config.yml
index 74cbe30a270..a3dbad1e7a3 100644
--- a/.evergreen/config.yml
+++ b/.evergreen/config.yml
@@ -3662,7 +3662,7 @@ tasks:
         type: setup
         params:
           updates:
-            - {key: NODE_LTS_VERSION, value: latest}
+            - {key: NODE_LTS_VERSION, value: '22'}
             - {key: NPM_VERSION, value: '9'}
       - func: install dependencies
       - func: check resource management
@@ -3676,7 +3676,7 @@ tasks:
           updates:
             - {key: VERSION, value: latest}
             - {key: TOPOLOGY, value: replica_set}
-            - {key: NODE_LTS_VERSION, value: latest}
+            - {key: NODE_LTS_VERSION, value: '22'}
       - func: install dependencies
       - func: bootstrap mongo-orchestration
       - func: check resource management feature integration
@@ -5085,6 +5085,7 @@ buildvariants:
       - test-tls-support-5.0
       - test-tls-support-4.4
       - test-tls-support-4.2
+    disable: true
   - name: windows-vsCurrent-large-gallium
     display_name: Windows Node16
     run_on: windows-vsCurrent-large
diff --git a/.evergreen/generate_evergreen_tasks.js b/.evergreen/generate_evergreen_tasks.js
index 0a916b7580f..ca11d5ff61e 100644
--- a/.evergreen/generate_evergreen_tasks.js
+++ b/.evergreen/generate_evergreen_tasks.js
@@ -436,12 +436,13 @@ for (const {
       display_name: `${osDisplayName} Node Latest`,
       run_on,
       expansions: { NODE_LTS_VERSION: 'latest' },
-      tasks: tasks.map(({ name }) => name)
+      tasks: tasks.map(({ name }) => name),
+      // TODO(NODE-6641): Unskip the smoke tests
+      disable: true
     };
     if (clientEncryption) {
       buildVariantData.expansions.CLIENT_ENCRYPTION = true;
     }
-
     BUILD_VARIANTS.push(buildVariantData);
   }
 }
@@ -549,7 +550,7 @@ SINGLETON_TASKS.push(
       tags: ['resource-management'],
       commands: [
         updateExpansions({
-          NODE_LTS_VERSION: 'latest',
+          NODE_LTS_VERSION: LATEST_LTS,
           NPM_VERSION: 9
         }),
         { func: 'install dependencies' },
@@ -563,7 +564,7 @@ SINGLETON_TASKS.push(
         updateExpansions({
           VERSION: 'latest',
           TOPOLOGY: 'replica_set',
-          NODE_LTS_VERSION: 'latest'
+          NODE_LTS_VERSION: LATEST_LTS 
         }),
         { func: 'install dependencies' },
         { func: 'bootstrap mongo-orchestration' },