ENH: Resample BOLD series to volumetric templates

Author: effigies

fmriprep/workflows/base.py

@@ -151,6 +151,7 @@ def init_single_subject_wf(subject_id: str):
     from niworkflows.utils.misc import fix_multi_T1w_source_name
     from niworkflows.utils.spaces import Reference
     from smriprep.workflows.anatomical import init_anat_fit_wf
+    from smriprep.workflows.outputs import init_template_iterator_wf
 
     from fmriprep.workflows.bold.base import init_bold_wf
 
@@ -310,7 +311,6 @@ def init_single_subject_wf(subject_id: str):
         skull_strip_fixed_seed=config.workflow.skull_strip_fixed_seed,
     )
 
-    # fmt:off
     workflow.connect([
         (inputnode, anat_fit_wf, [('subjects_dir', 'inputnode.subjects_dir')]),
         (bidssrc, bids_info, [(('t1w', fix_multi_T1w_source_name), 'in_file')]),
@@ -329,8 +329,18 @@ def init_single_subject_wf(subject_id: str):
         (bidssrc, ds_report_about, [(('t1w', fix_multi_T1w_source_name), 'source_file')]),
         (summary, ds_report_summary, [('out_report', 'in_file')]),
         (about, ds_report_about, [('out_report', 'in_file')]),
-    ])
-    # fmt:on
+    ])  # fmt:skip
+
+    # Set up the template iterator once, if used
+    if config.workflow.level == "full":
+        if spaces.get_spaces(nonstandard=False, dim=(3,)):
+            template_iterator_wf = init_template_iterator_wf(spaces=spaces)
+            workflow.connect([
+                (anat_fit_wf, template_iterator_wf, [
+                    ('outputnode.template', 'inputnode.template'),
+                    ('outputnode.anat2std_xfm', 'inputnode.anat2std_xfm'),
+                ]),
+            ])  # fmt:skip
 
     if config.workflow.anat_only:
         return clean_datasinks(workflow)
@@ -510,6 +520,18 @@ def init_single_subject_wf(subject_id: str):
                 ]),
             ])  # fmt:skip
 
+        if config.workflow.level == "full":
+            workflow.connect([
+                (template_iterator_wf, bold_wf, [
+                    ("outputnode.anat2std_xfm", "inputnode.anat2std_xfm"),
+                    ("outputnode.space", "inputnode.std_space"),
+                    ("outputnode.resolution", "inputnode.std_resolution"),
+                    ("outputnode.cohort", "inputnode.std_cohort"),
+                    ("outputnode.std_t1w", "inputnode.std_t1w"),
+                    ("outputnode.std_mask", "inputnode.std_mask"),
+                ]),
+            ])  # fmt:skip
+
     return clean_datasinks(workflow)
 
 

fmriprep/workflows/bold/base.py

@@ -198,6 +198,13 @@ def init_bold_wf(
                 "fmap_mask",
                 "fmap_id",
                 "sdc_method",
+                # Volumetric templates
+                "anat2std_xfm",
+                "std_space",
+                "std_resolution",
+                "std_cohort",
+                "std_t1w",
+                "std_mask",
             ],
         ),
         name="inputnode",
@@ -381,6 +388,59 @@ def init_bold_wf(
             (bold_anat_wf, ds_bold_t1_wf, [('outputnode.bold_file', 'inputnode.bold')]),
         ])  # fmt:skip
 
+    if spaces.get_spaces(nonstandard=False, dim=(3,)):
+        # Missing:
+        #  * Clipping BOLD after resampling
+        #  * Resampling parcellations
+        bold_std_wf = init_bold_volumetric_resample_wf(
+            metadata=all_metadata[0],
+            fieldmap_id=fieldmap_id if not multiecho else None,
+            omp_nthreads=omp_nthreads,
+            name='bold_std_wf',
+        )
+        ds_bold_std_wf = init_ds_volumes_wf(
+            bids_root=str(config.execution.bids_dir),
+            output_dir=fmriprep_dir,
+            multiecho=multiecho,
+            metadata=all_metadata[0],
+            name='ds_bold_std_wf',
+        )
+        ds_bold_std_wf.inputs.inputnode.source_files = bold_series
+
+        workflow.connect([
+            (inputnode, bold_std_wf, [
+                ("std_t1w", "inputnode.target_ref_file"),
+                ("std_mask", "inputnode.target_mask"),
+                ("anat2std_xfm", "inputnode.anat2std_xfm"),
+                ("fmap_ref", "inputnode.fmap_ref"),
+                ("fmap_coeff", "inputnode.fmap_coeff"),
+                ("fmap_id", "inputnode.fmap_id"),
+            ]),
+            (bold_fit_wf, bold_std_wf, [
+                ("outputnode.coreg_boldref", "inputnode.bold_ref_file"),
+                ("outputnode.boldref2fmap_xfm", "inputnode.boldref2fmap_xfm"),
+                ("outputnode.boldref2anat_xfm", "inputnode.boldref2anat_xfm"),
+            ]),
+            (bold_native_wf, bold_std_wf, [
+                ("outputnode.bold_minimal", "inputnode.bold_file"),
+                ("outputnode.motion_xfm", "inputnode.motion_xfm"),
+            ]),
+            (inputnode, ds_bold_std_wf, [
+                ('std_t1w', 'inputnode.ref_file'),
+                ('anat2std_xfm', 'inputnode.anat2std_xfm'),
+                ('std_space', 'inputnode.space'),
+                ('std_resolution', 'inputnode.resolution'),
+                ('std_cohort', 'inputnode.cohort'),
+            ]),
+            (bold_fit_wf, ds_bold_std_wf, [
+                ('outputnode.bold_mask', 'inputnode.bold_mask'),
+                ('outputnode.coreg_boldref', 'inputnode.bold_ref'),
+                ('outputnode.boldref2anat_xfm', 'inputnode.boldref2anat_xfm'),
+            ]),
+            (bold_native_wf, ds_bold_std_wf, [('outputnode.t2star_map', 'inputnode.t2star')]),
+            (bold_std_wf, ds_bold_std_wf, [('outputnode.bold_file', 'inputnode.bold')]),
+        ])  # fmt:skip
+
     # Fill-in datasinks of reportlets seen so far
     for node in workflow.list_node_names():
         if node.split(".")[-1].startswith("ds_report"):
@@ -629,90 +689,6 @@ def init_func_preproc_wf(bold_file, has_fieldmap=False):
     )
     bold_confounds_wf.get_node("inputnode").inputs.t1_transform_flags = [False]
 
-    if spaces.get_spaces(nonstandard=False, dim=(3,)):
-        # Apply transforms in 1 shot
-        bold_std_trans_wf = init_bold_std_trans_wf(
-            freesurfer=freesurfer,
-            mem_gb=mem_gb["resampled"],
-            omp_nthreads=omp_nthreads,
-            spaces=spaces,
-            multiecho=multiecho,
-            name="bold_std_trans_wf",
-            use_compression=not config.execution.low_mem,
-        )
-        bold_std_trans_wf.inputs.inputnode.fieldwarp = "identity"
-
-        # fmt:off
-        workflow.connect([
-            (inputnode, bold_std_trans_wf, [
-                ("template", "inputnode.templates"),
-                ("anat2std_xfm", "inputnode.anat2std_xfm"),
-                ("bold_file", "inputnode.name_source"),
-                ("t1w_aseg", "inputnode.bold_aseg"),
-                ("t1w_aparc", "inputnode.bold_aparc"),
-            ]),
-            (bold_final, bold_std_trans_wf, [
-                ("mask", "inputnode.bold_mask"),
-                ("t2star", "inputnode.t2star"),
-            ]),
-            (bold_reg_wf, bold_std_trans_wf, [
-                ("outputnode.itk_bold_to_t1", "inputnode.itk_bold_to_t1"),
-            ]),
-            (bold_std_trans_wf, outputnode, [
-                ("outputnode.bold_std", "bold_std"),
-                ("outputnode.bold_std_ref", "bold_std_ref"),
-                ("outputnode.bold_mask_std", "bold_mask_std"),
-            ]),
-        ])
-        # fmt:on
-
-        if freesurfer:
-            # fmt:off
-            workflow.connect([
-                (bold_std_trans_wf, func_derivatives_wf, [
-                    ("outputnode.bold_aseg_std", "inputnode.bold_aseg_std"),
-                    ("outputnode.bold_aparc_std", "inputnode.bold_aparc_std"),
-                ]),
-                (bold_std_trans_wf, outputnode, [
-                    ("outputnode.bold_aseg_std", "bold_aseg_std"),
-                    ("outputnode.bold_aparc_std", "bold_aparc_std"),
-                ]),
-            ])
-            # fmt:on
-
-        if not multiecho:
-            # fmt:off
-            workflow.connect([
-                (bold_split, bold_std_trans_wf, [("out_files", "inputnode.bold_split")]),
-                (bold_hmc_wf, bold_std_trans_wf, [
-                    ("outputnode.xforms", "inputnode.hmc_xforms"),
-                ]),
-            ])
-            # fmt:on
-        else:
-            # fmt:off
-            workflow.connect([
-                (split_opt_comb, bold_std_trans_wf, [("out_files", "inputnode.bold_split")]),
-                (bold_std_trans_wf, outputnode, [("outputnode.t2star_std", "t2star_std")]),
-            ])
-            # fmt:on
-
-            # Already applied in bold_bold_trans_wf, which inputs to bold_t2s_wf
-            bold_std_trans_wf.inputs.inputnode.hmc_xforms = "identity"
-
-        # fmt:off
-        # func_derivatives_wf internally parametrizes over snapshotted spaces.
-        workflow.connect([
-            (bold_std_trans_wf, func_derivatives_wf, [
-                ("outputnode.template", "inputnode.template"),
-                ("outputnode.spatial_reference", "inputnode.spatial_reference"),
-                ("outputnode.bold_std_ref", "inputnode.bold_std_ref"),
-                ("outputnode.bold_std", "inputnode.bold_std"),
-                ("outputnode.bold_mask_std", "inputnode.bold_mask_std"),
-            ]),
-        ])
-        # fmt:on
-
     # SURFACES ##################################################################################
     # Freesurfer
     if freesurfer and freesurfer_spaces: