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1 | 1 | The current neuroimaging workflow has matured into a large chain of processing and analysis steps involving a large number of experts, across imaging modalities and applications.
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2 |
| -The development and fast adoption of [_fMRIPrep_][1] have revealed that neuroscientists need tools that simplify their research workflow, provide visual reports and checkpoints, and engender trust in the tool itself. |
3 |
| -The _NiPreps (NeuroImaging Preprocessing toolS)_ framework extends _fMRIPrep_'s approach and principles to new imaging modalities. |
4 |
| -The vision for _NiPreps_ is to provide end-users (i.e., researchers) with applications that allow them to perform quality control smoothly and to prepare their data for modeling and statistical analysis. |
| 2 | +The development and fast adoption of [*fMRIPrep*][1] have revealed that neuroscientists need tools that simplify their research workflow, provide visual reports and checkpoints, and engender trust in the tool itself. |
| 3 | +The *NiPreps (NeuroImaging Preprocessing toolS)* framework extends *fMRIPrep*'s approach and principles to new imaging modalities. |
| 4 | +The vision for *NiPreps* is to provide end-users (i.e., researchers) with applications that allow them to perform quality control smoothly and to prepare their data for modeling and statistical analysis. |
5 | 5 |
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6 | 6 | ## Projects
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7 | 7 |
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8 |
| - * [_fMRIPrep_][1] ([GitHub](https://github.com/poldracklab/fmriprep)): fMRI Preprocessing |
9 |
| - * [_dMRIPrep_][6] ([GitHub](https://github.com/nipreps/dmriprep)): dMRI Preprocessing |
10 |
| - * [_sMRIPrep_][7] ([GitHub](https://github.com/poldracklab/smriprep)): Structural MRI Preprocessing |
11 |
| - * [_MRIQC_][8] ([GitHub](https://github.com/poldracklab/mriqc)): MRI quality control |
12 |
| - * [_SDCflows_][5] ([GitHub](https://github.com/nipreps/sdcflows)): Susceptibility-derived distortion correction (SDC) workflows |
13 |
| - * [_NiWorkflows_][4] ([GitHub](https://github.com/nipreps/niworkflows)): General/miscellaneous workflow utilities |
14 |
| - * [_TemplateFlow_][9]: A registry of neuroimaging templates and spatial mappings between them. |
| 8 | + * [*fMRIPrep*][1] ([GitHub](https://github.com/poldracklab/fmriprep)): fMRI Preprocessing |
| 9 | + * [*dMRIPrep*][6] ([GitHub](https://github.com/nipreps/dmriprep)): dMRI Preprocessing |
| 10 | + * [*sMRIPrep*][7] ([GitHub](https://github.com/poldracklab/smriprep)): Structural MRI Preprocessing |
| 11 | + * [*MRIQC*][8] ([GitHub](https://github.com/poldracklab/mriqc)): MRI quality control |
| 12 | + * [*SDCflows*][5] ([GitHub](https://github.com/nipreps/sdcflows)): Susceptibility-derived distortion correction (SDC) workflows |
| 13 | + * [*NiWorkflows*][4] ([GitHub](https://github.com/nipreps/niworkflows)): General/miscellaneous workflow utilities |
| 14 | + * [*TemplateFlow*][9]: A registry of neuroimaging templates and spatial mappings between them. |
15 | 15 |
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16 | 16 | ## Overview of the framework
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17 | 17 |
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18 |
| -The _NiPreps_ framework (Figure 1) encompasses a wide array of software projects organized into three layers of scientific software: |
| 18 | +The *NiPreps* framework (Figure 1) encompasses a wide array of software projects organized into three layers of scientific software: |
19 | 19 |
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20 |
| - * **Software infrastructure**: including quite mature projects such as [_NiPype_][2] and [_NiBabel_][3]; the standard specifications of the Brain Imaging Data Structure (BIDS, and BIDS-Derivatives); and some other tools such as _NiTransforms_ or _TemplateFlow_, under development. |
| 20 | + * **Software infrastructure**: including quite mature projects such as [*NiPype*][2] and [*NiBabel*][3]; the standard specifications of the Brain Imaging Data Structure (BIDS, and BIDS-Derivatives); and some other tools such as *NiTransforms* or *TemplateFlow*, under development. |
21 | 21 | These tools deliver low-level interfaces (e.g., data access to images and spatial transforms) and utilities (see Figure 1).
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22 | 22 | * **Middleware**: these are utilities that generalize their functionalities across the end-user tools.
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23 |
| - These utilities cover foundational processing methodologies (e.g., [_NiWorkflows_][4] and [_SDCflows_][5]), the crowdsourcing of metadata (e.g., _MRIQC Web-API_), and the support for deep learning models (_MRIQC-nets_). |
24 |
| - * **End-user tools such as _fMRIPrep_**: Some existing end-user tools include _sMRIPrep (Structural MRI Preprocessing)_, which lies in between an end-user tool and middleware, as it is involved in higher-level tools such as _fMRIPrep_. Finally, quality control tools (e.g., _MRIQC_) to be executed before any preprocessing happens. |
| 23 | + These utilities cover foundational processing methodologies (e.g., [*NiWorkflows*][4] and [*SDCflows*][5]), the crowdsourcing of metadata (e.g., *MRIQC Web-API*), and the support for deep learning models (*MRIQC-nets*). |
| 24 | + * **End-user tools such as *fMRIPrep***: Some existing end-user tools include *sMRIPrep (Structural MRI Preprocessing)*, which lies in between an end-user tool and middleware, as it is involved in higher-level tools such as *fMRIPrep*. Finally, quality control tools (e.g., *MRIQC*) to be executed before any preprocessing happens. |
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