Skip to content

Commit eaade15

Browse files
committed
enh: advance bhd2020 presentation
1 parent 2ce7393 commit eaade15

File tree

8 files changed

+177
-47
lines changed

8 files changed

+177
-47
lines changed

docs/assets/bhd2020/presentation.md

Lines changed: 177 additions & 47 deletions
Original file line numberDiff line numberDiff line change
@@ -6,31 +6,31 @@ layout: false
66
count: false
77

88
.middle.center[
9-
# Building communities around reproducible workflows
9+
# NiPreps | NeuroImaging PREProcessing toolS
1010

1111
<br />
1212
<br />
1313

1414
### O. Esteban
1515
#### CHUV | Lausanne University Hospital
1616

17-
###### [www.nipreps.org](https://www.nipreps.org)
17+
###### [www.nipreps.org/assets/bhd2020](https://www.nipreps.org/assets/bhd2020)
1818
]
1919

2020
---
2121
layout: false
2222
count: false
2323

2424
.middle.center[
25-
# Building communities around reproducible workflows
25+
# NiPreps | NeuroImaging PREProcessing toolS
2626

2727
<br />
2828
<br />
2929

3030
### O. Esteban
3131
#### CHUV | Lausanne University Hospital
3232

33-
###### [www.nipreps.org](https://www.nipreps.org)
33+
###### [www.nipreps.org/assets/bhd2020](https://www.nipreps.org/assets/bhd2020)
3434
]
3535

3636
???
@@ -42,9 +42,9 @@ layout: true
4242
class: section-separator
4343

4444
.perma-sidebar[
45-
## Data Processing
46-
### (Day 2, 15h CET)
47-
# Workflows
45+
## BHD2020
46+
### (Day 2, 14h CET)
47+
# *NiPreps*
4848

4949
<br />
5050
<br />
@@ -66,9 +66,9 @@ name: sidebar
6666
layout: true
6767

6868
.perma-sidebar[
69-
## Data Processing
70-
### (Day 2, 15h CET)
71-
# Workflows
69+
## BHD2020
70+
### (Day 2, 14h CET)
71+
# *NiPreps*
7272

7373
<br />
7474
<br />
@@ -88,6 +88,48 @@ layout: true
8888
---
8989
template: sidebar
9090

91+
# Outlook
92+
93+
---
94+
95+
## The research workflow of functional MRI (nowadays)
96+
<br />
97+
98+
<div style="margin: 10px 100px 10px 300px">
99+
<p align="center">
100+
<img src="../strother-2020.png" style="width: 100%" />
101+
</p>
102+
<p align="right">(source: next slide)</p>
103+
</div>
104+
105+
---
106+
107+
## The research workflow of functional MRI (2006)
108+
<br />
109+
110+
<div style="margin: 10px 100px 10px 300px">
111+
<p align="center">
112+
<img src="../strother-2006.png" style="width: 100%" />
113+
</p>
114+
<p align="right">(Strother, 2006; <a href="https://doi.org/10.1109/MEMB.2006.1607667">10.1109/MEMB.2006.1607667</a>)</p>
115+
</div>
116+
117+
---
118+
119+
## The research workflow of functional MRI (*a.B.*<sup>\*</sup>)
120+
<br />
121+
122+
<div style="margin: 10px 100px 10px 300px">
123+
<p align="center">
124+
<img src="../strother-2020-scanner.png" style="width: 100%" />
125+
</p>
126+
<p align="right">Adapted (<a href="https://doi.org/10.1109/MEMB.2006.1607667">Strother, 2006</a>)</p>
127+
</div>
128+
129+
<sup>\*</sup>a.B. = *after BIDS* (Brain Imaging Data Structure; [Gorgolewski et al. (2016)](https://doi.org/10.1038/sdata.2016.44))
130+
131+
---
132+
91133
## Neuroimaging is now mature
92134
* many excellent tools available (from specialized to foundational)
93135
* large toolboxes (AFNI, ANTs/ITK, FreeSurfer, FSL, Nilearn, SPM, etc.)
@@ -98,13 +140,16 @@ template: sidebar
98140

99141
* LOTS of data acquired everyday
100142

101-
## Workflows - game's on!
102-
* although many neuroimaging areas are still in search of methodological breakthroughs,
143+
## BIDS - A thrust of technology-driven development
144+
* A **uniform and complete interface** to data:
103145

104-
* challenges have moved on to the workflows:
105-
* workflows within traditional toolboxes - usually not flexible to adapt to new data
106-
* BIDS and BIDS-Apps.
146+
* **Uniform**: enables the workflow adapt to the data
147+
* **Complete**: enables validation and minimizes human-intervention
107148

149+
* Extensible reproducibility:
150+
151+
* [BIDS-Derivatives](https://bids-specification.readthedocs.io/en/latest/)
152+
* [BIDS-Apps](https://bids-apps.neuroimaging.io/) ([Gorgolewski et al., 2017](https://doi.org/10.1371/journal.pcbi.1005209))
108153

109154
???
110155

@@ -128,9 +173,9 @@ template: sidebar
128173
<img src="../narps.png" width="800px" alt="NARPS Paper" />
129174
</p>
130175

131-
(Botvinik-Nezer et al., 2020)
176+
([Botvinik-Nezer et al., 2020](https://doi.org/10.1038/s41586-020-2314-9))
132177

133-
Around 50% of teams used fMRIPrep'ed inputs.
178+
Around 50% of teams used *fMRIPrep*'ed inputs.
134179

135180
---
136181

@@ -288,27 +333,129 @@ Therefore, it is better to keep things that way (although some minimal efforts t
288333

289334
---
290335

336+
<div style="margin: 40px 100px 10px 320px">
337+
<p align="center">
338+
<img alt="The fMRIPrep workflow" src="../fmriprep-workflow-final.svg" width="100%" />
339+
</p>
340+
<p align="right">
341+
(<a href="https://doi.org/10.1038/s41592-018-0235-4">Esteban et al., 2019</a>)
342+
</p>
343+
</div>
344+
345+
---
346+
291347
## The *dMRIPrep* story
292348

293-
After the success of *fMRIPrep*, some neuroimagers asked "*when a diffussion MRI fMRIPrep?*"
349+
After the success of *fMRIPrep*, Dr. A. Keshavan asked "[*when a dMRIPrep?*](https://neurostars.org/t/dmriprep-an-fmriprep-for-diffusion/2385)"
294350

295351
## NeuroStars.org
296352
(please note this down)
297353

298-
--
299354

355+
---
300356

301-
Same situation in the field of diffusion MRI:
357+
## The *dMRIPrep* story
302358

303-
### Image Processing: Possible Guidelines for the Standardization & Clinical Applications (J. Veraart)
359+
After the success of *fMRIPrep*, Dr. A. Keshavan asked "[*when a dMRIPrep?*](https://neurostars.org/t/dmriprep-an-fmriprep-for-diffusion/2385)"
304360

305-
(https://www.ismrm.org/19/program_files/MIS15.htm)
361+
<p align="center">
362+
<img src="../veraart-2019.png" width="700px" alt="(Veraart, 2019)" />
363+
</p>
364+
[Image Processing: Possible Guidelines for the Standardization & Clinical Applications](https://www.ismrm.org/19/program_files/MIS15.htm)
365+
366+
(Veraart, 2019)
367+
368+
---
369+
370+
<div style="margin: 40px 40px 10px 250px">
371+
<img src="https://raw.githubusercontent.com/nipreps/dmriprep/master/docs/resources/figure1.svg" width="100%" alt="dMRIPrep workflow" />
372+
</div>
306373

307-
--
308374

309-
# Please join!
375+
### Please join!
310376

311-
Joseph, M.; Pisner, D.; Richie-Halford, A.; Lerma-Usabiaga, G.; Keshavan, A.; Kent, JD.; Cieslak, M.; Poldrack, RA.; Rokem, A.; Esteban, O.
377+
Joseph, M.; Pisner, D.; Richie-Halford, A.; Lerma-Usabiaga, G.; Keshavan, A.; Kent, JD.; Veraart, J.; Cieslak, M.; Poldrack, RA.; Rokem, A.; Esteban, O.
378+
379+
---
380+
381+
template: newsection
382+
layout: false
383+
384+
.middle.center[
385+
## Understanding what preprocessing is with visual reports
386+
]
387+
388+
---
389+
390+
## The individual report
391+
392+
<video controls="controls" width="70%"
393+
name="Video Name" src="../fmriprep-report.mov"></video>
394+
395+
???
396+
397+
Let's walk through one example of report.
398+
Reports have several sections, starting with a summary
399+
indicating the particularities of this dataset
400+
and workflow choices made based on the input data.
401+
402+
The anatomical section follows with several visualizations
403+
to assess the anatomical processing steps mentioned before,
404+
spatial normalization to template spaces (the flickering
405+
panel helps assess alignment) and finally surface reconstruction.
406+
407+
Then, all functional runs are concatenated, and all show the same
408+
structure.
409+
After an initial summary of this particular run,
410+
the alignment to the same subject's anatomical image is presented,
411+
with contours of the white and pial surfaces as cues.
412+
Next panel shows the brain mask and ROIs utilized by the CompCor
413+
denoising.
414+
For each run we then find some visualizations to assess the
415+
generated confounding signals.
416+
417+
After all functional runs are presented, the About section keeps
418+
information to aid reproducibility of results, such as the software's
419+
version, or the exact command line run.
420+
421+
The boilerplate is found next, with a text version shown by default
422+
and tabs to convert to Markdown and LaTeX.
423+
424+
Reports conclude with a list of encountered errors (if any).
425+
426+
---
427+
428+
## Reports are a crucial element to ensure transparency
429+
.pull-left[
430+
<p align="center">
431+
<img src="../wright-2019.png" width="400px" />
432+
</p>
433+
]
434+
435+
.pull-right[
436+
437+
.distribute[
438+
fMRIPrep generates one participant-wide report after execution.
439+
440+
Reports describe the data as found, and the steps applied
441+
(providing .blue[visual support to look inside the box]):
442+
443+
1. show researchers their data;
444+
445+
2. show how *fMRIPrep* interpreted the data (describing the actual preprocessing steps);
446+
447+
3. quality control of results, facilitating early error detection.
448+
]
449+
]
450+
451+
???
452+
453+
Therefore, reports have become a fundamental feature of fMRIPrep
454+
because they not only allow assessing the quality of the processing,
455+
but also provide an insight about the logic supporting such processing.
456+
457+
In other words, reports help respond to the what was done and the why was it done
458+
in addition to the how well it did.
312459

313460
---
314461

@@ -864,29 +1011,12 @@ As an open problem, validating the results of the tool remains extremely challen
8641011

8651012
---
8661013

867-
## The *NMiND* story
868-
869-
NMiND = *NeverMIND, this Neuroimaging Method Is Not Duplicated*
870-
871-
872-
### PIs worried about methodological duplicity
873-
874-
M. Milham, D. Fair, T. Satterthwaite, S. Ghosh, R. Poldrack, etc.
875-
876-
--
877-
878-
### NMiND's workgroups
879-
880-
*nosology* group, coding standards & patterns, sharing standards, testing standards, crediting contributors, funding strategy, benchmarking datasets.
881-
882-
### NMiND's nosology goals
883-
884-
* Consensus glossary of terms
885-
* Landscape the portfolio of methodological solutions along several experimental and computational dimensions
886-
* Organize and document a taxonomy along those dimensions
887-
* Index existing software (from unit methods to workflows) in the taxonomy
1014+
template: newsection
1015+
layout: false
8881016

889-
Please Join!
1017+
.middle.center[
1018+
# [github.com/nipreps](https://github.com/nipreps/)
1019+
]
8901020

8911021
---
8921022

docs/assets/strother-2006.png

31.9 KB
Loading

docs/assets/strother-2020-scanner.png

31.9 KB
Loading

docs/assets/strother-2020.png

32.7 KB
Loading

docs/assets/veraart-2019.png

650 KB
Loading
File renamed without changes.

0 commit comments

Comments
 (0)