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22 | 22 | from nipype.interfaces.traits_extension import isdefined
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23 | 23 |
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24 | 24 |
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| 25 | +class BuildConnectomeInputSpec(CommandLineInputSpec): |
| 26 | + in_file = File(exists=True, argstr='%s', mandatory=True, position=-3, |
| 27 | + desc='input tractography') |
| 28 | + in_parc = File(exists=True, argstr='%s', position=-2, |
| 29 | + desc='parcellation file') |
| 30 | + out_file = File( |
| 31 | + 'connectome.csv', argstr='%s', mandatory=True, position=-1, |
| 32 | + usedefault=True, desc='output file after processing') |
| 33 | + |
| 34 | + nthreads = traits.Int( |
| 35 | + argstr='-nthreads %d', desc='number of threads. if zero, the number' |
| 36 | + ' of available cpus will be used') |
| 37 | + |
| 38 | + vox_lookup = traits.Bool( |
| 39 | + argstr='-assignment_voxel_lookup', |
| 40 | + desc='use a simple voxel lookup value at each streamline endpoint') |
| 41 | + search_radius = traits.Float( |
| 42 | + argstr='-assignment_radial_search %f', |
| 43 | + desc='perform a radial search from each streamline endpoint to locate ' |
| 44 | + 'the nearest node. Argument is the maximum radius in mm; if no node is' |
| 45 | + ' found within this radius, the streamline endpoint is not assigned to' |
| 46 | + ' any node.') |
| 47 | + search_reverse = traits.Float( |
| 48 | + argstr='-assignment_reverse_search %f', |
| 49 | + desc='traverse from each streamline endpoint inwards along the ' |
| 50 | + 'streamline, in search of the last node traversed by the streamline. ' |
| 51 | + 'Argument is the maximum traversal length in mm (set to 0 to allow ' |
| 52 | + 'search to continue to the streamline midpoint).') |
| 53 | + search_forward = traits.Float( |
| 54 | + argstr='-assignment_forward_search %f', |
| 55 | + desc='project the streamline forwards from the endpoint in search of a' |
| 56 | + 'parcellation node voxel. Argument is the maximum traversal length in ' |
| 57 | + 'mm.') |
| 58 | + |
| 59 | + metric = traits.Enum( |
| 60 | + 'count', 'meanlength', 'invlength', 'invnodevolume', 'mean_scalar', |
| 61 | + 'invlength_invnodevolume', argstr='-metric %s', desc='specify the edge' |
| 62 | + ' weight metric') |
| 63 | + |
| 64 | + in_scalar = File( |
| 65 | + exists=True, argstr='-image %s', desc='provide the associated image ' |
| 66 | + 'for the mean_scalar metric') |
| 67 | + |
| 68 | + in_weights = File( |
| 69 | + exists=True, argstr='-tck_weights_in %s', desc='specify a text scalar ' |
| 70 | + 'file containing the streamline weights') |
| 71 | + |
| 72 | + keep_unassigned = traits.Bool( |
| 73 | + argstr='-keep_unassigned', desc='By default, the program discards the' |
| 74 | + ' information regarding those streamlines that are not successfully ' |
| 75 | + 'assigned to a node pair. Set this option to keep these values (will ' |
| 76 | + 'be the first row/column in the output matrix)') |
| 77 | + zero_diagonal = traits.Bool( |
| 78 | + argstr='-zero_diagonal', desc='set all diagonal entries in the matrix ' |
| 79 | + 'to zero (these represent streamlines that connect to the same node at' |
| 80 | + ' both ends)') |
| 81 | + |
| 82 | + |
| 83 | +class BuildConnectomeOutputSpec(TraitedSpec): |
| 84 | + out_file = File(exists=True, desc='the output response file') |
| 85 | + |
| 86 | + |
| 87 | +class BuildConnectome(MRTrix3Base): |
| 88 | + |
| 89 | + """ |
| 90 | + Generate a connectome matrix from a streamlines file and a node |
| 91 | + parcellation image |
| 92 | +
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| 93 | + Example |
| 94 | + ------- |
| 95 | +
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| 96 | + >>> import nipype.interfaces.mrtrix3 as mrt |
| 97 | + >>> mat = mrt.BuildConnectome() |
| 98 | + >>> mat.inputs.in_file = 'aparc+aseg.nii.gz' |
| 99 | + >>> mat.inputs.in_config = 'mrtrix3_labelconfig.txt' |
| 100 | + >>> mat.cmdline # doctest: +ELLIPSIS |
| 101 | + 'labelconfig aparc+aseg.nii.gz mrtrix3_labelconfig.txt parcellation.mif' |
| 102 | + >>> mat.run() # doctest: +SKIP |
| 103 | + """ |
| 104 | + |
| 105 | + _cmd = 'labelconfig' |
| 106 | + input_spec = BuildConnectomeInputSpec |
| 107 | + output_spec = BuildConnectomeOutputSpec |
| 108 | + |
| 109 | + def _parse_inputs(self, skip=None): |
| 110 | + if skip is None: |
| 111 | + skip = [] |
| 112 | + |
| 113 | + if not isdefined(self.inputs.in_config): |
| 114 | + from distutils.spawn import find_executable |
| 115 | + path = find_executable(self._cmd) |
| 116 | + if path is None: |
| 117 | + path = os.getenv(MRTRIX3_HOME, '/opt/mrtrix3') |
| 118 | + else: |
| 119 | + path = op.dirname(op.dirname(path)) |
| 120 | + |
| 121 | + self.inputs.in_config = op.join( |
| 122 | + path, 'src/dwi/tractography/connectomics/' |
| 123 | + 'example_configs/fs_default.txt') |
| 124 | + |
| 125 | + return super(BuildConnectome, self)._parse_inputs(skip=skip) |
| 126 | + |
| 127 | + def _list_outputs(self): |
| 128 | + outputs = self.output_spec().get() |
| 129 | + outputs['out_file'] = op.abspath(self.inputs.out_file) |
| 130 | + return outputs |
| 131 | + |
| 132 | + |
25 | 133 | class LabelConfigInputSpec(CommandLineInputSpec):
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26 | 134 | in_file = File(exists=True, argstr='%s', mandatory=True, position=-3,
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27 | 135 | desc='input anatomical image')
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