HML Examples

HML Examples

NGS examples

Locus	Method	Interpretation Format	HML	Other info
A B	NGS	GL String	hml_0_9_4-example1-classI-AB-ngs-sanger.hml
DRB1	NGS	GL String	hml_0_9_4-example2-classII-DRB1-ngs.hml

Examples of older technologies in HML 0.94

Locus	Method	Interpretation Format	HML	Other info
A B C		Haploid	hml_0_9_4-example3-nointerp.xml	three samples; no primary data or interpretation
DRB1 DQB1 DPB1	SBT	Haploid (allele code and allele)	hml_0_9_4-example4-sbtsanger.xml
A B C	SBT	Haploid (allele code and allele)	hml_0_9_4-example5-gssp.xml
DPA1 DPB1	SSO	Haploid (allele)	hml_0_9_4-example6-sso.xml
DPA1

Examples from previous versions of HML converted to v0.93

| Locus | Method | Interpretation
Format | HML | Other info | | ----- | ------ | --------------------- | ------- | ------- || | A | DNA | allele code | case.05.1a.v030.xml | Lab 999 typed a sample for center 123 for the ABDR project for NMDP ID: 444-333-2. The typing was performed on Jan 23, 2004. The results are:
A0102, A0103
A0103, A0106 | | A | DNA | genotype list | case.05.1b.v030.xml
case.05.1.v093.xml | (same as above, but reported as genotype list instead of allele code)<br >Lab 999 typed a sample for center 123 for the ABDR project for NMDP ID: 444-333-2. The typing was performed on Jan 23, 2004. The results are:
A0102, A0103
A0103, A0106 | | B | SBT | genotype list | ex_4_1.v033.xml
ex_4_1.v093.xml| In this case there is an intronic or exon1 gSSP reagent that is uninformative for our local interpretation. The gssp tag with no contents is an indicator of a hemizygous product | | B | SBT | genotype list | ex_4_2.v033.xml
ex_4_2.v093.xml| In this case there is an intronic or exon1 gSSP reagent that is uninformative for our local interpretation. The gssp tag with no contents is an indicator of a hemizygous product | | B | SBT | genotype list | ex_4_3.v033.xml<br > ex_4_3.v093.xml| example showing GSSP as sequence instead of registered-name | | DRB1 | SBT | genotype list | ex_5_1.v033.xml
ex_5_1.v093.xml| There is no generic sequence in this example. It contains GSSPs that are specific for DRB113 and DRB115 | | DRB1 | SBT | genotype list | ex_6_1.v033.xml
ex_6_1.v093.xml| This is a homozygous sample with no generic sequence. This is up-front GSSP that is DR13 specific. | | 2DL1
2DL2
2DL3
2DL4
2DL5
2DS1
2DS2
2DS3
2DS4
2DS5
3DL1
3DL2
3DL3
3DS1
| SSO | genotype list | case.06.1.v030.xml
case.06.1.v093.xml| Lab 999 typed a sample for center 789 for a project entitled "KIR". The typing was performed on Sep 8, 2008. They tested fourteen KIR genes and reported presence/absence for each,along with the probe information. Each locus was reported in its own 'typing' HML element. | | 2DL1
2DL2
2DL3
2DL4
2DL5
2DS1
2DS2
2DS3
2DS4
2DS5
3DL1
3DL2
3DL3
3DS1
| SSO | genotype list | case.06.2.v030.xml
case.06.2.v093.xml| Same as above (6.1) except for each sample (one, in this case), all loci were reported in a single 'interpretation' element. |