s0.2mdn.net seem pretty prevalent and blocking it I haven't found single site to break.
I would tried mtv.ca and cbs.com to recheck that whitelisting s0.2mdn.net is still needed, but those are geo-fenced and doesn't play in my region unfortunately.
Would you reconsider to remove s0.2mdn.net from whitelist https://github.com/notracking/hosts-blocklists-scripts/blob/master/hostnames.whitelist.txt ?
Thank you and cheers