diff --git a/doc/nrf/app_dev/device_guides/fem/fem_nRF21540_optional_properties.rst b/doc/nrf/app_dev/device_guides/fem/fem_nRF21540_optional_properties.rst
index 4fb4b316f9ff..16bed5c8ffb7 100644
--- a/doc/nrf/app_dev/device_guides/fem/fem_nRF21540_optional_properties.rst
+++ b/doc/nrf/app_dev/device_guides/fem/fem_nRF21540_optional_properties.rst
@@ -30,8 +30,9 @@ The following properties are optional for use with the :ref:`GPIO <ug_radio_fem_
 
 * Properties that control the timing of interface signals:
 
-  * ``tx-en-settle-time-us`` - Minimal time interval between asserting the ``TX_EN`` signal and starting the radio transmission, in microseconds.
-  * ``rx-en-settle-time-us`` - Minimal time interval between asserting the ``RX_EN`` signal and starting the radio transmission, in microseconds.
+  * ``tx-en-settle-time-us`` - Time between asserting the ``TX_EN`` signal and the readiness of the PA for transmission, in microseconds.
+    The value of :kconfig:option:`CONFIG_MPSL_FEM_NRF21540_PA_LEAD_TIME_ADDITIONAL_US` option is added to the ``tx-en-settle-time-us`` to calculate the moment in time when the ``TX_EN`` signal is asserted before transmission.
+  * ``rx-en-settle-time-us`` - Time between asserting the ``RX_EN`` signal and the readiness of the LNA for reception, in microseconds.
 
     .. note::
         Values for these two properties cannot be higher than the Radio Ramp-Up time defined by :c:macro:`TX_RAMP_UP_TIME` and :c:macro:`RX_RAMP_UP_TIME`.
diff --git a/doc/nrf/app_dev/device_guides/fem/fem_nrf21540_gpio.rst b/doc/nrf/app_dev/device_guides/fem/fem_nrf21540_gpio.rst
index c4ec6d45b9b7..186e76ff1ec7 100644
--- a/doc/nrf/app_dev/device_guides/fem/fem_nrf21540_gpio.rst
+++ b/doc/nrf/app_dev/device_guides/fem/fem_nrf21540_gpio.rst
@@ -43,6 +43,7 @@ To use nRF21540 in GPIO mode, complete the following steps:
    * :kconfig:option:`CONFIG_MPSL_FEM_NRF21540_TX_GAIN_DB_POUTB`
    * :kconfig:option:`CONFIG_MPSL_FEM_NRF21540_RX_GAIN_DB`
    * :kconfig:option:`CONFIG_MPSL_FEM_NRF21540_RUNTIME_PA_GAIN_CONTROL`
+   * :kconfig:option:`CONFIG_MPSL_FEM_NRF21540_PA_LEAD_TIME_ADDITIONAL_US`
 
 #. Optionally replace the node name ``name_of_fem_node``.
 #. Replace the pin numbers provided for each of the required properties:
diff --git a/subsys/mpsl/fem/Kconfig b/subsys/mpsl/fem/Kconfig
index 7791a6ab18fa..f1f87f336632 100644
--- a/subsys/mpsl/fem/Kconfig
+++ b/subsys/mpsl/fem/Kconfig
@@ -208,6 +208,18 @@ config MPSL_FEM_NRF21540_RUNTIME_PA_GAIN_CONTROL
 
 	  If this option is disabled the PA gain is constant and equal MPSL_FEM_NRF21540_TX_GAIN_DB.
 
+config MPSL_FEM_NRF21540_PA_LEAD_TIME_ADDITIONAL_US
+	int "Additional lead time in microseconds by which the PA of the nRF21540 is enabled earlier."
+	default 15
+	help
+	  Radio protocol drivers in the nRF Connect SDK usually set the target time point
+	  when the PA of a Front-End Module is expected to be fully ramped-up and ready
+	  for a transmission as the moment of the EVENTS_READY event of the RADIO peripheral.
+	  However the RF power on the SoC output starts to rise before this event.
+	  To avoid any spurious emission, at the moment when RF power starts to rise
+	  on the SoC output the PA of the FEM should be fully ramped-up.
+	  This parameter is added to the PA tx-en-settle-time-us device tree property
+	  to enable the PA of the FEM earlier and avoid spurious emission.
 
 endif   # (MPSL_FEM_NRF21540_GPIO || MPSL_FEM_NRF21540_GPIO_SPI) && MPSL_FEM
 
diff --git a/subsys/mpsl/fem/nrf21540_gpio/mpsl_fem_nrf21540_gpio.c b/subsys/mpsl/fem/nrf21540_gpio/mpsl_fem_nrf21540_gpio.c
index 7a7e7234f3e4..e7d32d12171b 100644
--- a/subsys/mpsl/fem/nrf21540_gpio/mpsl_fem_nrf21540_gpio.c
+++ b/subsys/mpsl/fem/nrf21540_gpio/mpsl_fem_nrf21540_gpio.c
@@ -63,7 +63,8 @@ static int fem_nrf21540_gpio_configure(void)
 		.fem_config = {
 			.pa_time_gap_us  =
 				DT_PROP(DT_NODELABEL(nrf_radio_fem),
-					tx_en_settle_time_us),
+					tx_en_settle_time_us) +
+					CONFIG_MPSL_FEM_NRF21540_PA_LEAD_TIME_ADDITIONAL_US,
 			.lna_time_gap_us =
 				DT_PROP(DT_NODELABEL(nrf_radio_fem),
 					rx_en_settle_time_us),
diff --git a/subsys/mpsl/fem/nrf21540_gpio_spi/mpsl_fem_nrf21540_gpio_spi.c b/subsys/mpsl/fem/nrf21540_gpio_spi/mpsl_fem_nrf21540_gpio_spi.c
index ba4e26cf2e14..8aaf5fef657a 100644
--- a/subsys/mpsl/fem/nrf21540_gpio_spi/mpsl_fem_nrf21540_gpio_spi.c
+++ b/subsys/mpsl/fem/nrf21540_gpio_spi/mpsl_fem_nrf21540_gpio_spi.c
@@ -144,7 +144,8 @@ static int fem_nrf21540_gpio_spi_configure(void)
 		.fem_config = {
 			.pa_time_gap_us  =
 				DT_PROP(DT_NODELABEL(nrf_radio_fem),
-					tx_en_settle_time_us),
+					tx_en_settle_time_us) +
+					CONFIG_MPSL_FEM_NRF21540_PA_LEAD_TIME_ADDITIONAL_US,
 			.lna_time_gap_us =
 				DT_PROP(DT_NODELABEL(nrf_radio_fem),
 					rx_en_settle_time_us),