diff --git a/samples/boards/nordic/system_off/boards/nrf54l15dk_nrf54l05_cpuapp_retained_mem.overlay b/samples/boards/nordic/system_off/boards/nrf54l15dk_nrf54l05_cpuapp_retained_mem.overlay
new file mode 100644
index 00000000000..6f4a9be80f9
--- /dev/null
+++ b/samples/boards/nordic/system_off/boards/nrf54l15dk_nrf54l05_cpuapp_retained_mem.overlay
@@ -0,0 +1,25 @@
+/ {
+	cpuapp_sram@20017000 {
+		compatible = "zephyr,memory-region", "mmio-sram";
+		reg = <0x20017000 DT_SIZE_K(4)>;
+		zephyr,memory-region = "RetainedMem";
+		status = "okay";
+
+		retainedmem0: retainedmem {
+			compatible = "zephyr,retained-ram";
+			status = "okay";
+		};
+	};
+
+	aliases {
+		retainedmemdevice = &retainedmem0;
+	};
+};
+
+&cpuapp_sram {
+	/* Shrink SRAM size to avoid overlap with retained memory region:
+	 * 96 - 4 = 92KB = 0x17000
+	 */
+	reg = <0x20000000 0x17000>;
+	ranges = <0x0 0x20000000 0x17000>;
+};
diff --git a/samples/boards/nordic/system_off/boards/nrf54l15dk_nrf54l10_cpuapp_retained_mem.overlay b/samples/boards/nordic/system_off/boards/nrf54l15dk_nrf54l10_cpuapp_retained_mem.overlay
new file mode 100644
index 00000000000..9705cf335a7
--- /dev/null
+++ b/samples/boards/nordic/system_off/boards/nrf54l15dk_nrf54l10_cpuapp_retained_mem.overlay
@@ -0,0 +1,25 @@
+/ {
+	cpuapp_sram@2002f000 {
+		compatible = "zephyr,memory-region", "mmio-sram";
+		reg = <0x2002f000 DT_SIZE_K(4)>;
+		zephyr,memory-region = "RetainedMem";
+		status = "okay";
+
+		retainedmem0: retainedmem {
+			compatible = "zephyr,retained-ram";
+			status = "okay";
+		};
+	};
+
+	aliases {
+		retainedmemdevice = &retainedmem0;
+	};
+};
+
+&cpuapp_sram {
+	/* Shrink SRAM size to avoid overlap with retained memory region:
+	 * 192 - 4 = 188KB = 0x2f000
+	 */
+	reg = <0x20000000 0x2f000>;
+	ranges = <0x0 0x20000000 0x2f000>;
+};
diff --git a/samples/boards/nordic/system_off/sample.yaml b/samples/boards/nordic/system_off/sample.yaml
index ab6a12aeb16..18f629c4e54 100644
--- a/samples/boards/nordic/system_off/sample.yaml
+++ b/samples/boards/nordic/system_off/sample.yaml
@@ -4,16 +4,25 @@ common:
   tags: power
 tests:
   sample.boards.nrf.system_off:
-    build_only: true
     integration_platforms:
       - nrf52840dk/nrf52840
     platform_allow:
-      - nrf54l15dk/nrf54l15/cpuapp
+      - nrf51dk/nrf51822
       - nrf52840dk/nrf52840
       - nrf52dk/nrf52832
-      - nrf51dk/nrf51822
+      - nrf5340dk/nrf5340/cpuapp
+      - nrf54l15dk/nrf54l05/cpuapp
+      - nrf54l15dk/nrf54l10/cpuapp
+      - nrf54l15dk/nrf54l15/cpuapp
+    harness: console
+    harness_config:
+      type: multi_line
+      ordered: true
+      regex:
+        - "system off demo"
+        - "Retained data not supported"
+        - "Entering system off; press sw0 to restart"
   sample.boards.nrf.system_off.nrf_retained:
-    build_only: true
     integration_platforms:
       - nrf52840dk/nrf52840
     platform_allow:
@@ -21,17 +30,76 @@ tests:
       - nrf52dk/nrf52832
     extra_configs:
       - CONFIG_APP_USE_NRF_RETENTION=y
+    harness: console
+    harness_config:
+      type: multi_line
+      ordered: true
+      regex:
+        - "system off demo"
+        - "Retained data: INVALID"
+        - "Boot count: 1"
+        - "Off count: 0"
+        - "Active Ticks:"
+        - "Entering system off; press sw0 to restart"
   sample.boards.nrf.system_off.retained_mem:
     extra_args: DTC_OVERLAY_FILE="boards/nrf54l15dk_nrf54l15_cpuapp_retained_mem.overlay"
-    build_only: true
     platform_allow:
       - nrf54l15dk/nrf54l15/cpuapp
     extra_configs:
       - CONFIG_APP_USE_RETAINED_MEM=y
       - CONFIG_RETAINED_MEM=y
+    harness: console
+    harness_config:
+      type: multi_line
+      ordered: true
+      regex:
+        - "system off demo"
+        - "Retained data: INVALID"
+        - "Boot count: 1"
+        - "Off count: 0"
+        - "Active Ticks:"
+        - "Entering system off; press sw0 to restart"
   sample.boards.nrf.system_off.grtc_wakeup:
-    build_only: true
     platform_allow:
       - nrf54l15dk/nrf54l15/cpuapp
     extra_configs:
       - CONFIG_GRTC_WAKEUP_ENABLE=y
+    harness: console
+    harness_config:
+      type: multi_line
+      ordered: true
+      regex:
+        - "system off demo"
+        - "Retained data not supported"
+        - "Entering system off; wait 2 seconds to restart"
+        - "system off demo"
+        - "Retained data not supported"
+        - "Entering system off; wait 2 seconds to restart"
+        - "system off demo"
+        - "Retained data not supported"
+        - "Entering system off; wait 2 seconds to restart"
+  sample.boards.nrf.system_off.retained_mem.grtc_wakeup:
+    extra_args: DTC_OVERLAY_FILE="boards/nrf54l15dk_nrf54l15_cpuapp_retained_mem.overlay"
+    platform_allow:
+      - nrf54l15dk/nrf54l15/cpuapp
+    extra_configs:
+      - CONFIG_APP_USE_RETAINED_MEM=y
+      - CONFIG_GRTC_WAKEUP_ENABLE=y
+      - CONFIG_RETAINED_MEM=y
+    harness: console
+    harness_config:
+      type: multi_line
+      ordered: true
+      regex:
+        - "system off demo"
+        - "Retained data: INVALID"
+        - "Boot count: 1"
+        - "Off count: 0"
+        - "Active Ticks:"
+        - "Entering system off; wait 2 seconds to restart"
+        - "system off demo"
+        - "Retained data: valid"
+        - "Boot count: 2"
+        - "Off count: 1"
+        - "Active Ticks:"
+        - "Entering system off; wait 2 seconds to restart"
diff --git a/samples/subsys/settings/boards/nrf54l15dk_nrf54l05_cpuapp.conf b/samples/subsys/settings/boards/nrf54l15dk_nrf54l05_cpuapp.conf
new file mode 100644
index 00000000000..3746c13c741
--- /dev/null
+++ b/samples/subsys/settings/boards/nrf54l15dk_nrf54l05_cpuapp.conf
@@ -0,0 +1,2 @@
+CONFIG_NVS=y
+CONFIG_SETTINGS_NVS=y
diff --git a/samples/subsys/settings/boards/nrf54l15dk_nrf54l10_cpuapp.conf b/samples/subsys/settings/boards/nrf54l15dk_nrf54l10_cpuapp.conf
new file mode 100644
index 00000000000..3746c13c741
--- /dev/null
+++ b/samples/subsys/settings/boards/nrf54l15dk_nrf54l10_cpuapp.conf
@@ -0,0 +1,2 @@
+CONFIG_NVS=y
+CONFIG_SETTINGS_NVS=y
diff --git a/samples/subsys/settings/sample.yaml b/samples/subsys/settings/sample.yaml
index 09d191c352a..a19c9baaa0d 100644
--- a/samples/subsys/settings/sample.yaml
+++ b/samples/subsys/settings/sample.yaml
@@ -12,6 +12,8 @@ tests:
       - native_sim
       - native_sim/native/64
       - mr_canhubk3
+      - nrf54l15dk/nrf54l05/cpuapp
+      - nrf54l15dk/nrf54l10/cpuapp
       - nrf54l15dk/nrf54l15/cpuapp
       - nrf54h20dk/nrf54h20/cpuapp
     integration_platforms:
diff --git a/tests/drivers/flash/common/testcase.yaml b/tests/drivers/flash/common/testcase.yaml
index 977fea9d0ed..5c8e755dc4d 100644
--- a/tests/drivers/flash/common/testcase.yaml
+++ b/tests/drivers/flash/common/testcase.yaml
@@ -38,6 +38,8 @@ tests:
       - mimxrt1060_evk
   drivers.flash.common.no_explicit_erase:
     platform_allow:
+      - nrf54l15dk/nrf54l05/cpuapp
+      - nrf54l15dk/nrf54l10/cpuapp
       - nrf54l15dk/nrf54l15/cpuapp
       - nrf54h20dk/nrf54h20/cpuapp
   drivers.flash.common.tfm_ns:
diff --git a/tests/drivers/gpio/gpio_basic_api/boards/nrf54l15dk_nrf54l15_cpuflpr.overlay b/tests/drivers/gpio/gpio_basic_api/boards/nrf54l15dk_nrf54l15_cpuflpr.overlay
new file mode 100644
index 00000000000..e26399cd4c4
--- /dev/null
+++ b/tests/drivers/gpio/gpio_basic_api/boards/nrf54l15dk_nrf54l15_cpuflpr.overlay
@@ -0,0 +1 @@
+#include "nrf54l15dk_nrf54l15_cpuapp.overlay"
diff --git a/tests/drivers/gpio/gpio_basic_api/boards/nrf54l15dk_nrf54l15_cpuflpr_xip.overlay b/tests/drivers/gpio/gpio_basic_api/boards/nrf54l15dk_nrf54l15_cpuflpr_xip.overlay
new file mode 100644
index 00000000000..e26399cd4c4
--- /dev/null
+++ b/tests/drivers/gpio/gpio_basic_api/boards/nrf54l15dk_nrf54l15_cpuflpr_xip.overlay
@@ -0,0 +1 @@
+#include "nrf54l15dk_nrf54l15_cpuapp.overlay"
diff --git a/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l05_cpuapp.conf b/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l05_cpuapp.conf
new file mode 100644
index 00000000000..c15ba3ed96d
--- /dev/null
+++ b/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l05_cpuapp.conf
@@ -0,0 +1 @@
+CONFIG_POWEROFF=y
diff --git a/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l05_cpuapp.overlay b/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l05_cpuapp.overlay
new file mode 100644
index 00000000000..300823ba9c0
--- /dev/null
+++ b/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l05_cpuapp.overlay
@@ -0,0 +1,25 @@
+/ {
+	cpuapp_sram@20017000 {
+		compatible = "zephyr,memory-region", "mmio-sram";
+		reg = <0x20017000 DT_SIZE_K(4)>;
+		zephyr,memory-region = "RetainedMem";
+		status = "okay";
+
+		retainedmem0: retainedmem {
+			compatible = "zephyr,retained-ram";
+			status = "okay";
+		};
+	};
+
+	aliases {
+		retainedmemtestdevice = &retainedmem0;
+	};
+};
+
+&cpuapp_sram {
+	/* Shrink SRAM size to avoid overlap with retained memory region:
+	 * 96 - 4 = 92KB = 0x17000
+	 */
+	reg = <0x20000000 0x17000>;
+	ranges = <0x0 0x20000000 0x17000>;
+};
diff --git a/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l10_cpuapp.conf b/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l10_cpuapp.conf
new file mode 100644
index 00000000000..c15ba3ed96d
--- /dev/null
+++ b/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l10_cpuapp.conf
@@ -0,0 +1 @@
+CONFIG_POWEROFF=y
diff --git a/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l10_cpuapp.overlay b/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l10_cpuapp.overlay
new file mode 100644
index 00000000000..7005c29f307
--- /dev/null
+++ b/tests/drivers/retained_mem/api/boards/nrf54l15dk_nrf54l10_cpuapp.overlay
@@ -0,0 +1,25 @@
+/ {
+	cpuapp_sram@2002f000 {
+		compatible = "zephyr,memory-region", "mmio-sram";
+		reg = <0x2002f000 DT_SIZE_K(4)>;
+		zephyr,memory-region = "RetainedMem";
+		status = "okay";
+
+		retainedmem0: retainedmem {
+			compatible = "zephyr,retained-ram";
+			status = "okay";
+		};
+	};
+
+	aliases {
+		retainedmemtestdevice = &retainedmem0;
+	};
+};
+
+&cpuapp_sram {
+	/* Shrink SRAM size to avoid overlap with retained memory region:
+	 * 192 - 4 = 188KB = 0x2f000
+	 */
+	reg = <0x20000000 0x2f000>;
+	ranges = <0x0 0x20000000 0x2f000>;
+};
diff --git a/tests/drivers/retained_mem/api/testcase.yaml b/tests/drivers/retained_mem/api/testcase.yaml
index 02f7c7c8b27..f6b6844a1b4 100644
--- a/tests/drivers/retained_mem/api/testcase.yaml
+++ b/tests/drivers/retained_mem/api/testcase.yaml
@@ -9,6 +9,8 @@ tests:
       - qemu_cortex_m3
       - nrf54h20dk/nrf54h20/cpuapp
       - nrf54h20dk/nrf54h20/cpurad
+      - nrf54l15dk/nrf54l05/cpuapp
+      - nrf54l15dk/nrf54l10/cpuapp
       - nrf54l15dk/nrf54l15/cpuapp
     tags:
       - drivers