diff --git a/drivers/misc/nordic_vpr_launcher/Kconfig b/drivers/misc/nordic_vpr_launcher/Kconfig
index 6aeabcd251c..d00bcc583f9 100644
--- a/drivers/misc/nordic_vpr_launcher/Kconfig
+++ b/drivers/misc/nordic_vpr_launcher/Kconfig
@@ -4,7 +4,8 @@
 config NORDIC_VPR_LAUNCHER
 	bool "Nordic VPR coprocessor launcher"
 	default y
-	depends on DT_HAS_NORDIC_NRF_VPR_COPROCESSOR_ENABLED
+	depends on DT_HAS_NORDIC_NRF_VPR_COPROCESSOR_ENABLED && \
+		   $(dt_compat_any_has_prop,$(DT_COMPAT_NORDIC_NRF_VPR_COPROCESSOR),execution-memory)
 	help
 	  When enabled, the VPR coprocessors will be automatically launched
 	  during system initialization.
diff --git a/drivers/misc/nordic_vpr_launcher/nordic_vpr_launcher.c b/drivers/misc/nordic_vpr_launcher/nordic_vpr_launcher.c
index 5bd43f87fb9..b28ebec6b5c 100644
--- a/drivers/misc/nordic_vpr_launcher/nordic_vpr_launcher.c
+++ b/drivers/misc/nordic_vpr_launcher/nordic_vpr_launcher.c
@@ -34,6 +34,11 @@ static int nordic_vpr_launcher_init(const struct device *dev)
 {
 	const struct nordic_vpr_launcher_config *config = dev->config;
 
+	/* Do nothing if execution memory is not specified for a given VPR. */
+	if (config->exec_addr == 0) {
+		return 0;
+	}
+
 #if DT_ANY_INST_HAS_PROP_STATUS_OKAY(source_memory)
 	if (config->size > 0U) {
 		LOG_DBG("Loading VPR (%p) from %p to %p (%zu bytes)", config->vpr,
@@ -63,16 +68,20 @@ static int nordic_vpr_launcher_init(const struct device *dev)
 	(DT_REG_ADDR(node_id) +                                                                    \
 	 COND_CODE_0(DT_FIXED_PARTITION_EXISTS(node_id), (0), (DT_REG_ADDR(DT_GPARENT(node_id)))))
 
+#define NEEDS_COPYING(inst) UTIL_AND(DT_INST_NODE_HAS_PROP(inst, execution_memory),                \
+				     DT_INST_NODE_HAS_PROP(inst, source_memory))
+
 #define NORDIC_VPR_LAUNCHER_DEFINE(inst)                                                           \
-	IF_ENABLED(DT_INST_NODE_HAS_PROP(inst, source_memory),                                     \
+	IF_ENABLED(NEEDS_COPYING(inst),                                                            \
 		   (BUILD_ASSERT((DT_REG_SIZE(DT_INST_PHANDLE(inst, execution_memory)) <=          \
 				  DT_REG_SIZE(DT_INST_PHANDLE(inst, source_memory))),              \
 				 "Execution memory exceeds source memory size");))                 \
                                                                                                    \
 	static const struct nordic_vpr_launcher_config config##inst = {                            \
 		.vpr = (NRF_VPR_Type *)DT_INST_REG_ADDR(inst),                                     \
-		.exec_addr = VPR_ADDR(DT_INST_PHANDLE(inst, execution_memory)),                    \
-		IF_ENABLED(DT_INST_NODE_HAS_PROP(inst, source_memory),                             \
+		IF_ENABLED(DT_INST_NODE_HAS_PROP(inst, execution_memory),                          \
+			   (.exec_addr = VPR_ADDR(DT_INST_PHANDLE(inst, execution_memory)),))      \
+		IF_ENABLED(NEEDS_COPYING(inst),                                                    \
 			   (.src_addr = VPR_ADDR(DT_INST_PHANDLE(inst, source_memory)),            \
 			    .size = DT_REG_SIZE(DT_INST_PHANDLE(inst, execution_memory)),))};      \
                                                                                                    \
diff --git a/drivers/pinctrl/pinctrl_nrf.c b/drivers/pinctrl/pinctrl_nrf.c
index 3f909b3e990..5e4cd6fb549 100644
--- a/drivers/pinctrl/pinctrl_nrf.c
+++ b/drivers/pinctrl/pinctrl_nrf.c
@@ -112,12 +112,17 @@ static const nrf_gpio_pin_drive_t drive_modes[NRF_DRIVE_COUNT] = {
 #define NRF_PSEL_TDM(reg, line) ((NRF_TDM_Type *)reg)->PSEL.line
 #endif
 
-#if defined(CONFIG_SOC_NRF54L15_CPUAPP)
-#if DT_HAS_COMPAT_STATUS_OKAY(nordic_nrfe_mspi_controller) || defined(CONFIG_MSPI_NRFE)
-#define NRF_PSEL_SDP_MSPI(psel)                                                                    \
+#if DT_HAS_COMPAT_STATUS_OKAY(nordic_nrfe_mspi_controller) || \
+	defined(CONFIG_MSPI_NRFE) || \
+	DT_ANY_COMPAT_HAS_PROP_STATUS_OKAY(nordic_nrf_vpr_coprocessor, pinctrl_0)
+#if defined(CONFIG_SOC_SERIES_NRF54LX)
+#define NRF_PSEL_SDP_MSPI(psel) \
 	nrf_gpio_pin_control_select(psel, NRF_GPIO_PIN_SEL_VPR);
+#elif defined(CONFIG_SOC_SERIES_NRF54HX)
+/* On nRF54H, pin routing is controlled by secure domain, via UICR. */
+#define NRF_PSEL_SDP_MSPI(psel)
 #endif
-#endif
+#endif /* DT_HAS_COMPAT_STATUS_OKAY(nordic_nrfe_mspi_controller) || ... */
 
 int pinctrl_configure_pins(const pinctrl_soc_pin_t *pins, uint8_t pin_cnt,
 			   uintptr_t reg)
@@ -472,8 +477,7 @@ int pinctrl_configure_pins(const pinctrl_soc_pin_t *pins, uint8_t pin_cnt,
 			input = NRF_GPIO_PIN_INPUT_CONNECT;
 			break;
 #endif /* defined(NRF_PSEL_TWIS) */
-#if defined(CONFIG_SOC_NRF54L15_CPUAPP)
-#if DT_HAS_COMPAT_STATUS_OKAY(nordic_nrfe_mspi_controller)
+#if defined(NRF_PSEL_SDP_MSPI)
 		case NRF_FUN_SDP_MSPI_CS0:
 		case NRF_FUN_SDP_MSPI_CS1:
 		case NRF_FUN_SDP_MSPI_CS2:
@@ -492,8 +496,7 @@ int pinctrl_configure_pins(const pinctrl_soc_pin_t *pins, uint8_t pin_cnt,
 			dir = NRF_GPIO_PIN_DIR_OUTPUT;
 			input = NRF_GPIO_PIN_INPUT_CONNECT;
 			break;
-#endif /* DT_HAS_COMPAT_STATUS_OKAY(nordic_nrfe_mspi_controller) */
-#endif /* CONFIG_SOC_NRF54L15_CPUAPP */
+#endif /* defined(NRF_PSEL_SDP_MSPI) */
 		default:
 			return -ENOTSUP;
 		}
diff --git a/dts/bindings/riscv/nordic,nrf-vpr-coprocessor.yaml b/dts/bindings/riscv/nordic,nrf-vpr-coprocessor.yaml
index 43deaeb6d3b..8760e828880 100644
--- a/dts/bindings/riscv/nordic,nrf-vpr-coprocessor.yaml
+++ b/dts/bindings/riscv/nordic,nrf-vpr-coprocessor.yaml
@@ -9,14 +9,17 @@ description: |
   VPR is a RISC-V CPU implementation. VPR instances are exposed to other CPUs as
   peripherals.
 
-include: base.yaml
+include: [base.yaml, pinctrl-device.yaml]
 
 properties:
   execution-memory:
     type: phandle
-    required: true
     description: |
-      Memory area from which the VPR core will execute.
+      Memory area from which the VPR code will execute.
+      If not specified, the VPR coprocessor will not be launched automatically
+      by the nordic_vpr_launcher driver when the node is enabled. In such case,
+      the launching is supposed to be done explicitly by the user code, in some
+      custom way presumably.
 
   source-memory:
     type: phandle
diff --git a/soc/nordic/common/nrf54hx_nrf92x_mpu_regions.c b/soc/nordic/common/nrf54hx_nrf92x_mpu_regions.c
index b76fac86bcd..a9e8b3de7a9 100644
--- a/soc/nordic/common/nrf54hx_nrf92x_mpu_regions.c
+++ b/soc/nordic/common/nrf54hx_nrf92x_mpu_regions.c
@@ -18,6 +18,9 @@
 #define CAN121_SIZE	DT_REG_SIZE_BY_NAME(DT_NODELABEL(can121), message_ram) + \
 			DT_REG_SIZE_BY_NAME(DT_NODELABEL(can121), m_can)
 
+#define SOFTPERIPH_BASE	DT_REG_ADDR(DT_NODELABEL(softperiph_ram))
+#define SOFTPERIPH_SIZE	DT_REG_SIZE(DT_NODELABEL(softperiph_ram))
+
 static struct arm_mpu_region mpu_regions[] = {
 	MPU_REGION_ENTRY("FLASH_0",
 			 CONFIG_FLASH_BASE_ADDRESS,
@@ -40,6 +43,10 @@ static struct arm_mpu_region mpu_regions[] = {
 	MPU_REGION_ENTRY("CAN121_MCAN", CAN121_BASE,
 			 REGION_RAM_NOCACHE_ATTR(CAN121_BASE, CAN121_SIZE)),
 #endif
+#if DT_NODE_EXISTS(DT_NODELABEL(softperiph_ram))
+	MPU_REGION_ENTRY("SOFTPERIPH_RAM", SOFTPERIPH_BASE,
+			 REGION_RAM_NOCACHE_ATTR(SOFTPERIPH_BASE, SOFTPERIPH_SIZE)),
+#endif
 };
 
 const struct arm_mpu_config mpu_config = {