diff --git a/samples/boards/nordic/spis_wakeup/boards/nrf54h20dk_nrf54h20_cpuapp.conf b/samples/boards/nordic/spis_wakeup/boards/nrf54h20dk_nrf54h20_cpuapp.conf
new file mode 100644
index 00000000000..61643e48fbf
--- /dev/null
+++ b/samples/boards/nordic/spis_wakeup/boards/nrf54h20dk_nrf54h20_cpuapp.conf
@@ -0,0 +1,4 @@
+# Copyright (c) 2025 Nordic Semiconductor ASA
+# SPDX-License-Identifier: Apache-2.0
+
+CONFIG_SOC_NRF54H20_CPURAD_ENABLE=y