diff --git a/.github/workflows/wheels.yml b/.github/workflows/wheels.yml
index 4e34445..26d5fbb 100644
--- a/.github/workflows/wheels.yml
+++ b/.github/workflows/wheels.yml
@@ -78,7 +78,11 @@ jobs:
             python: "cp313t"
           - buildplat: [ macos13, macosx_x86_64, openblas ]
             python: "cp314t"
-
+        include:
+          - buildplat: [ ubuntu-22.04, pyodide_wasm32, "" ]
+            python: "cp312"
+          - buildplat: [ ubuntu-22.04, pyodide_wasm32, "" ]
+            python: "cp313"
     env:
       IS_32_BIT: ${{ matrix.buildplat[1] == 'win32' }}  # used in a cibw_*.sh script
 
@@ -139,17 +143,20 @@ jobs:
             echo "CIBW_ENVIRONMENT_MACOS=PKG_CONFIG_PATH=$PWD/.openblas" >> "$GITHUB_ENV"
           fi
 
-      # Used to run cibuildwheel
-      - uses: actions/setup-python@a26af69be951a213d495a4c3e4e4022e16d87065 # v5.6.0
-        with:
-          python-version: "3.13"
+      - name: Pyodide setup
+        if: ${{ matrix.buildplat[1] == 'pyodide_wasm32' }}
+        run: |
+          echo "CIBW_PLATFORM=pyodide" >> "$GITHUB_ENV"
 
-      - name: Build wheel
+      - name: Build wheels
+        uses: pypa/cibuildwheel@c923d83ad9c1bc00211c5041d0c3f73294ff88f6
         env:
           CIBW_BUILD: ${{ matrix.python }}-${{ matrix.buildplat[1] }}
-        run: |
-          python -m pip install cibuildwheel==3.1.1
-          python -m cibuildwheel numpy-src --config-file cibuildwheel.toml --output-dir ./dist
+          SRC: ${{ github.workspace }}/numpy-src
+        with:
+           package-dir: numpy-src
+           output-dir: dist
+           config-file: cibuildwheel.toml
 
       - uses: actions/upload-artifact@ea165f8d65b6e75b540449e92b4886f43607fa02 # v4.6.2
         with:
diff --git a/cibuildwheel.toml b/cibuildwheel.toml
index beacb56..2f38915 100644
--- a/cibuildwheel.toml
+++ b/cibuildwheel.toml
@@ -34,3 +34,13 @@ repair-wheel-command = "bash -el ./tools/wheels/repair_windows.sh {wheel} {dest_
 select = ["*-win32"]
 config-settings = {setup-args = ["--vsenv", "-Dallow-noblas=true"], build-dir="build"}
 repair-wheel-command = ""
+
+[tool.cibuildwheel.pyodide]
+before-test = "pip install -r $SRC/requirements/emscripten_test_requirements.txt"
+# Pyodide ensures that the wheels are already repaired by auditwheel-emscripten
+repair-wheel-command = ""
+test-command = "python -m pytest --pyargs numpy -m 'not slow'"
+
+[tool.cibuildwheel.pyodide.config-settings]
+build-dir = "build"
+setup-args = ["--cross-file=$SRC/tools/ci/emscripten/emscripten.meson.cross", "-Dblas=none", "-Dlapack=none"]