From 5ae69f32cff2bf7fc625a785b1fb0a6c0f3bf4b8 Mon Sep 17 00:00:00 2001 From: Dragon-AI Agent Date: Tue, 20 May 2025 22:21:08 +0000 Subject: [PATCH] Add stratum corneum of esophageal epithelium term Addresses issue #3423. Added new term for stratum corneum of esophageal epithelium with ID UBERON:8910024 as requested. @dragon-ai-agent --- src/ontology/uberon-edit.obo | 9 +++++++++ 1 file changed, 9 insertions(+) diff --git a/src/ontology/uberon-edit.obo b/src/ontology/uberon-edit.obo index d1d6c46d4a..90000b6b17 100644 --- a/src/ontology/uberon-edit.obo +++ b/src/ontology/uberon-edit.obo @@ -225063,6 +225063,15 @@ relationship: dc-contributor https://orcid.org/0000-0002-1909-7004 relationship: in_taxon NCBITaxon:6692 ! Pleocyemata relationship: part_of UBERON:8910000 ! stomatogastric nervous system +[Term] +id: UBERON:8910024 +name: stratum corneum of esophageal epithelium +def: "The outermost layer of the stratified squamous epithelium lining the esophagus, composed of several layers of flattened, anucleated keratinocytes called corneocytes. It forms the primary protective barrier against mechanical, chemical, and microbial insults, while regulating permeability and contributing to tissue integrity. This layer is characterized by corneocytes embedded in a lipid-rich extracellular matrix, providing mechanical reinforcement and maintaining essential barrier functions of the esophageal lining." [PMID:21126700, PMID:26019440, doi:10.1038/gimo15] +is_a: UBERON:0010304 ! non-keratinized stratified squamous epithelium +relationship: dc-contributor https://orcid.org/0009-0005-7919-4905 +relationship: part_of UBERON:0001976 ! epithelium of esophagus +relationship: superficial_to UBERON:8700002 ! stratum spinosum of esophageal epithelium + [Typedef] id: aboral_to name: aboral to