diff --git a/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/AdviceUtil.java b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/AdviceUtil.java
new file mode 100644
index 000000000000..c860547f9c6a
--- /dev/null
+++ b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/AdviceUtil.java
@@ -0,0 +1,31 @@
+/*
+ * Copyright The OpenTelemetry Authors
+ * SPDX-License-Identifier: Apache-2.0
+ */
+
+package io.opentelemetry.javaagent.instrumentation.internal.classloader;
+
+import io.opentelemetry.javaagent.extension.instrumentation.TypeTransformer;
+import io.opentelemetry.javaagent.tooling.Utils;
+import io.opentelemetry.javaagent.tooling.bytebuddy.ExceptionHandlers;
+import net.bytebuddy.agent.builder.AgentBuilder;
+import net.bytebuddy.asm.Advice;
+import net.bytebuddy.description.method.MethodDescription;
+import net.bytebuddy.matcher.ElementMatcher;
+
+class AdviceUtil {
+  private static final Advice.WithCustomMapping adviceMapping =
+      Advice.withCustomMapping()
+          .with(new Advice.AssignReturned.Factory().withSuppressed(Throwable.class));
+
+  static void applyInlineAdvice(
+      TypeTransformer transformer, ElementMatcher<MethodDescription> matcher, String adviceClass) {
+    transformer.applyTransformer(
+        new AgentBuilder.Transformer.ForAdvice(adviceMapping)
+            .include(Utils.getBootstrapProxy(), Utils.getAgentClassLoader())
+            .withExceptionHandler(ExceptionHandlers.defaultExceptionHandler())
+            .advice(matcher, adviceClass));
+  }
+
+  private AdviceUtil() {}
+}
diff --git a/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/BootDelegationInstrumentation.java b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/BootDelegationInstrumentation.java
index a18778912b6a..e40cea1c41f3 100644
--- a/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/BootDelegationInstrumentation.java
+++ b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/BootDelegationInstrumentation.java
@@ -6,6 +6,7 @@
 package io.opentelemetry.javaagent.instrumentation.internal.classloader;
 
 import static io.opentelemetry.javaagent.extension.matcher.AgentElementMatchers.extendsClass;
+import static io.opentelemetry.javaagent.instrumentation.internal.classloader.AdviceUtil.applyInlineAdvice;
 import static net.bytebuddy.matcher.ElementMatchers.isMethod;
 import static net.bytebuddy.matcher.ElementMatchers.isProtected;
 import static net.bytebuddy.matcher.ElementMatchers.isPublic;
@@ -19,9 +20,6 @@
 import io.opentelemetry.javaagent.bootstrap.CallDepth;
 import io.opentelemetry.javaagent.extension.instrumentation.TypeInstrumentation;
 import io.opentelemetry.javaagent.extension.instrumentation.TypeTransformer;
-import io.opentelemetry.javaagent.tooling.Utils;
-import io.opentelemetry.javaagent.tooling.bytebuddy.ExceptionHandlers;
-import net.bytebuddy.agent.builder.AgentBuilder;
 import net.bytebuddy.asm.Advice;
 import net.bytebuddy.description.method.MethodDescription;
 import net.bytebuddy.description.type.TypeDescription;
@@ -62,12 +60,7 @@ public void transform(TypeTransformer transformer) {
             .and(isPublic().or(isProtected()))
             .and(not(isStatic()));
     // Inline instrumentation to prevent problems with invokedynamic-recursion
-    transformer.applyTransformer(
-        new AgentBuilder.Transformer.ForAdvice()
-            .include(Utils.getBootstrapProxy(), Utils.getAgentClassLoader())
-            .withExceptionHandler(ExceptionHandlers.defaultExceptionHandler())
-            .advice(
-                methodMatcher, BootDelegationInstrumentation.class.getName() + "$LoadClassAdvice"));
+    applyInlineAdvice(transformer, methodMatcher, this.getClass().getName() + "$LoadClassAdvice");
   }
 
   @SuppressWarnings("unused")
diff --git a/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/DefineClassInstrumentation.java b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/DefineClassInstrumentation.java
index 20ca23bb8b0d..612fc815be85 100644
--- a/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/DefineClassInstrumentation.java
+++ b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/DefineClassInstrumentation.java
@@ -5,6 +5,7 @@
 
 package io.opentelemetry.javaagent.instrumentation.internal.classloader;
 
+import static io.opentelemetry.javaagent.instrumentation.internal.classloader.AdviceUtil.applyInlineAdvice;
 import static net.bytebuddy.matcher.ElementMatchers.named;
 import static net.bytebuddy.matcher.ElementMatchers.takesArguments;
 
@@ -27,16 +28,18 @@ public ElementMatcher<TypeDescription> typeMatcher() {
 
   @Override
   public void transform(TypeTransformer transformer) {
-    transformer.applyAdviceToMethod(
+    applyInlineAdvice(
+        transformer,
         named("defineClass")
             .and(
                 takesArguments(
                     String.class, byte[].class, int.class, int.class, ProtectionDomain.class)),
-        DefineClassInstrumentation.class.getName() + "$DefineClassAdvice");
-    transformer.applyAdviceToMethod(
+        this.getClass().getName() + "$DefineClassAdvice");
+    applyInlineAdvice(
+        transformer,
         named("defineClass")
             .and(takesArguments(String.class, ByteBuffer.class, ProtectionDomain.class)),
-        DefineClassInstrumentation.class.getName() + "$DefineClassWithThreeArgsAdvice");
+        this.getClass().getName() + "$DefineClassWithThreeArgsAdvice");
   }
 
   @SuppressWarnings("unused")
diff --git a/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/LoadInjectedClassInstrumentation.java b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/LoadInjectedClassInstrumentation.java
index fcf37f8a24b6..81aea69de8b7 100644
--- a/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/LoadInjectedClassInstrumentation.java
+++ b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/LoadInjectedClassInstrumentation.java
@@ -6,6 +6,7 @@
 package io.opentelemetry.javaagent.instrumentation.internal.classloader;
 
 import static io.opentelemetry.javaagent.extension.matcher.AgentElementMatchers.extendsClass;
+import static io.opentelemetry.javaagent.instrumentation.internal.classloader.AdviceUtil.applyInlineAdvice;
 import static net.bytebuddy.matcher.ElementMatchers.isMethod;
 import static net.bytebuddy.matcher.ElementMatchers.isProtected;
 import static net.bytebuddy.matcher.ElementMatchers.isPublic;
@@ -18,9 +19,6 @@
 import io.opentelemetry.javaagent.bootstrap.InjectedClassHelper;
 import io.opentelemetry.javaagent.extension.instrumentation.TypeInstrumentation;
 import io.opentelemetry.javaagent.extension.instrumentation.TypeTransformer;
-import io.opentelemetry.javaagent.tooling.Utils;
-import io.opentelemetry.javaagent.tooling.bytebuddy.ExceptionHandlers;
-import net.bytebuddy.agent.builder.AgentBuilder;
 import net.bytebuddy.asm.Advice;
 import net.bytebuddy.description.method.MethodDescription;
 import net.bytebuddy.description.type.TypeDescription;
@@ -52,13 +50,7 @@ public void transform(TypeTransformer transformer) {
             .and(isPublic().or(isProtected()))
             .and(not(isStatic()));
     // Inline instrumentation to prevent problems with invokedynamic-recursion
-    transformer.applyTransformer(
-        new AgentBuilder.Transformer.ForAdvice()
-            .include(Utils.getBootstrapProxy(), Utils.getAgentClassLoader())
-            .withExceptionHandler(ExceptionHandlers.defaultExceptionHandler())
-            .advice(
-                methodMatcher,
-                LoadInjectedClassInstrumentation.class.getName() + "$LoadClassAdvice"));
+    applyInlineAdvice(transformer, methodMatcher, this.getClass().getName() + "$LoadClassAdvice");
   }
 
   @SuppressWarnings("unused")
diff --git a/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/ResourceInjectionInstrumentation.java b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/ResourceInjectionInstrumentation.java
index 65076ce645d7..cd83896bca2b 100644
--- a/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/ResourceInjectionInstrumentation.java
+++ b/instrumentation/internal/internal-class-loader/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/internal/classloader/ResourceInjectionInstrumentation.java
@@ -6,7 +6,7 @@
 package io.opentelemetry.javaagent.instrumentation.internal.classloader;
 
 import static io.opentelemetry.javaagent.extension.matcher.AgentElementMatchers.extendsClass;
-import static net.bytebuddy.matcher.ElementMatchers.isMethod;
+import static io.opentelemetry.javaagent.instrumentation.internal.classloader.AdviceUtil.applyInlineAdvice;
 import static net.bytebuddy.matcher.ElementMatchers.named;
 import static net.bytebuddy.matcher.ElementMatchers.returns;
 import static net.bytebuddy.matcher.ElementMatchers.takesArguments;
@@ -37,24 +37,20 @@ public ElementMatcher<TypeDescription> typeMatcher() {
 
   @Override
   public void transform(TypeTransformer transformer) {
-    transformer.applyAdviceToMethod(
-        isMethod()
-            .and(named("getResource"))
-            .and(takesArguments(String.class))
-            .and(returns(URL.class)),
-        ResourceInjectionInstrumentation.class.getName() + "$GetResourceAdvice");
-    transformer.applyAdviceToMethod(
-        isMethod()
-            .and(named("getResources"))
-            .and(takesArguments(String.class))
-            .and(returns(Enumeration.class)),
-        ResourceInjectionInstrumentation.class.getName() + "$GetResourcesAdvice");
-    transformer.applyAdviceToMethod(
-        isMethod()
-            .and(named("getResourceAsStream"))
+    applyInlineAdvice(
+        transformer,
+        named("getResource").and(takesArguments(String.class)).and(returns(URL.class)),
+        this.getClass().getName() + "$GetResourceAdvice");
+    applyInlineAdvice(
+        transformer,
+        named("getResources").and(takesArguments(String.class)).and(returns(Enumeration.class)),
+        this.getClass().getName() + "$GetResourcesAdvice");
+    applyInlineAdvice(
+        transformer,
+        named("getResourceAsStream")
             .and(takesArguments(String.class))
             .and(returns(InputStream.class)),
-        ResourceInjectionInstrumentation.class.getName() + "$GetResourceAsStreamAdvice");
+        this.getClass().getName() + "$GetResourceAsStreamAdvice");
   }
 
   @SuppressWarnings("unused")
diff --git a/javaagent-tooling/src/main/java/io/opentelemetry/javaagent/tooling/AgentInstaller.java b/javaagent-tooling/src/main/java/io/opentelemetry/javaagent/tooling/AgentInstaller.java
index d84226806580..5a08597845f1 100644
--- a/javaagent-tooling/src/main/java/io/opentelemetry/javaagent/tooling/AgentInstaller.java
+++ b/javaagent-tooling/src/main/java/io/opentelemetry/javaagent/tooling/AgentInstaller.java
@@ -56,6 +56,7 @@
 import java.util.HashMap;
 import java.util.List;
 import java.util.Map;
+import java.util.Objects;
 import java.util.logging.LogManager;
 import java.util.logging.Logger;
 import java.util.stream.Stream;
@@ -225,12 +226,11 @@ private static void installEarlyInstrumentation(
 
     AgentBuilder.Identified.Extendable extendableAgentBuilder =
         agentBuilder
-            .ignore(
-                target ->
-                    // turn off after instrumentation is installed, exclude classes in
-                    // java.lang.invoke to avoid circularity when bootstrapping indy instrumentation
-                    instrumentationInstalled
-                        || target.getTypeName().startsWith("java.lang.invoke."))
+            // ignore classes that are not in boot loader, this also ignores classes in our agent
+            // loader
+            .ignore(any(), Objects::nonNull)
+            // turn off after instrumentation is installed
+            .or(target -> instrumentationInstalled)
             .type(none())
             .transform(
                 (builder, typeDescription, classLoader, module, protectionDomain) -> builder);