diff --git a/instrumentation/cassandra/cassandra-4-common/testing/build.gradle.kts b/instrumentation/cassandra/cassandra-4-common/testing/build.gradle.kts
index 8147a0167158..d8cac710ab13 100644
--- a/instrumentation/cassandra/cassandra-4-common/testing/build.gradle.kts
+++ b/instrumentation/cassandra/cassandra-4-common/testing/build.gradle.kts
@@ -5,6 +5,6 @@ plugins {
 dependencies {
   api(project(":testing-common"))
 
+  compileOnly("com.datastax.oss:java-driver-core:4.0.0")
   implementation("org.testcontainers:testcontainers")
-  implementation("com.datastax.oss:java-driver-core:4.0.0")
 }
diff --git a/instrumentation/cassandra/cassandra-4.4/javaagent/build.gradle.kts b/instrumentation/cassandra/cassandra-4.4/javaagent/build.gradle.kts
index 5f310ed60624..91b4dcf1f56e 100644
--- a/instrumentation/cassandra/cassandra-4.4/javaagent/build.gradle.kts
+++ b/instrumentation/cassandra/cassandra-4.4/javaagent/build.gradle.kts
@@ -9,12 +9,23 @@ muzzle {
     versions.set("[4.4,]")
     assertInverse.set(true)
   }
+  pass {
+    group.set("org.apache.cassandra")
+    module.set("java-driver-core")
+    versions.set("(,)")
+    assertInverse.set(true)
+  }
 }
 
+val latestDepTest = findProperty("testLatestDeps") as Boolean
 dependencies {
   implementation(project(":instrumentation:cassandra:cassandra-4.4:library"))
 
-  library("com.datastax.oss:java-driver-core:4.4.0")
+  if (latestDepTest) {
+    library("org.apache.cassandra:java-driver-core:4.18.0")
+  } else {
+    library("com.datastax.oss:java-driver-core:4.4.0")
+  }
 
   compileOnly("com.google.auto.value:auto-value-annotations")
   annotationProcessor("com.google.auto.value:auto-value")
diff --git a/instrumentation/cassandra/cassandra-4.4/library/build.gradle.kts b/instrumentation/cassandra/cassandra-4.4/library/build.gradle.kts
index 13a5a8037356..79d0375fd9e5 100644
--- a/instrumentation/cassandra/cassandra-4.4/library/build.gradle.kts
+++ b/instrumentation/cassandra/cassandra-4.4/library/build.gradle.kts
@@ -2,8 +2,13 @@ plugins {
   id("otel.library-instrumentation")
 }
 
+val latestDepTest = findProperty("testLatestDeps") as Boolean
 dependencies {
-  library("com.datastax.oss:java-driver-core:4.4.0")
+  if (latestDepTest) {
+    library("org.apache.cassandra:java-driver-core:4.18.0")
+  } else {
+    library("com.datastax.oss:java-driver-core:4.4.0")
+  }
 
   compileOnly("com.google.auto.value:auto-value-annotations")
   annotationProcessor("com.google.auto.value:auto-value")
diff --git a/instrumentation/cassandra/cassandra-4.4/testing/build.gradle.kts b/instrumentation/cassandra/cassandra-4.4/testing/build.gradle.kts
index faaad8aa7951..da0dd5e93c56 100644
--- a/instrumentation/cassandra/cassandra-4.4/testing/build.gradle.kts
+++ b/instrumentation/cassandra/cassandra-4.4/testing/build.gradle.kts
@@ -5,7 +5,7 @@ plugins {
 dependencies {
   api(project(":testing-common"))
 
-  implementation("com.datastax.oss:java-driver-core:4.4.0")
+  compileOnly("com.datastax.oss:java-driver-core:4.4.0")
   implementation("io.projectreactor:reactor-core:3.5.3")
 
   api(project(":instrumentation:cassandra:cassandra-4-common:testing"))