diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/CHANGELOG.md b/instrumentation-genai/opentelemetry-instrumentation-vertexai/CHANGELOG.md
index 5b66ea7972..0fae39d7d0 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/CHANGELOG.md
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/CHANGELOG.md
@@ -15,3 +15,5 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
   ([#3208](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3208))
 - VertexAI emit user, system, and assistant events
   ([#3203](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3203))
+- Add Vertex gen AI response span attributes
+  ([#3227](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3227))
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/events.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/events.py
index 5d011006de..d8746242c1 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/events.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/events.py
@@ -20,6 +20,11 @@
 schematized in YAML and the Weaver tool supports it.
 """
 
+from __future__ import annotations
+
+from dataclasses import asdict, dataclass
+from typing import Literal
+
 from opentelemetry._events import Event
 from opentelemetry.semconv._incubating.attributes import gen_ai_attributes
 from opentelemetry.util.types import AnyValue
@@ -89,3 +94,46 @@ def system_event(
         },
         body=body,
     )
+
+
+@dataclass
+class ChoiceMessage:
+    """The message field for a gen_ai.choice event"""
+
+    content: AnyValue = None
+    role: str = "assistant"
+
+
+FinishReason = Literal[
+    "content_filter", "error", "length", "stop", "tool_calls"
+]
+
+
+# TODO add tool calls
+# https://github.com/open-telemetry/opentelemetry-python-contrib/issues/3216
+def choice_event(
+    *,
+    finish_reason: FinishReason | str,
+    index: int,
+    message: ChoiceMessage,
+) -> Event:
+    """Creates a choice event, which describes the Gen AI response message.
+    https://github.com/open-telemetry/semantic-conventions/blob/v1.28.0/docs/gen-ai/gen-ai-events.md#event-gen_aichoice
+    """
+    body: dict[str, AnyValue] = {
+        "finish_reason": finish_reason,
+        "index": index,
+        "message": asdict(
+            message,
+            # filter nulls
+            dict_factory=lambda kvs: {k: v for (k, v) in kvs if v is not None},
+        ),
+    }
+
+    return Event(
+        name="gen_ai.choice",
+        attributes={
+            gen_ai_attributes.GEN_AI_SYSTEM: gen_ai_attributes.GenAiSystemValues.VERTEX_AI.value,
+        },
+        body=body,
+    )
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py
index fe0a9cdf60..fa8baefa9a 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py
@@ -25,9 +25,11 @@
 from opentelemetry.instrumentation.vertexai.utils import (
     GenerateContentParams,
     get_genai_request_attributes,
+    get_genai_response_attributes,
     get_server_attributes,
     get_span_name,
     request_to_events,
+    response_to_events,
 )
 from opentelemetry.trace import SpanKind, Tracer
 
@@ -113,7 +115,7 @@ def traced_method(
             name=span_name,
             kind=SpanKind.CLIENT,
             attributes=span_attributes,
-        ) as _span:
+        ) as span:
             for event in request_to_events(
                 params=params, capture_content=capture_content
             ):
@@ -121,17 +123,20 @@ def traced_method(
 
             # TODO: set error.type attribute
             # https://github.com/open-telemetry/semantic-conventions/blob/main/docs/gen-ai/gen-ai-spans.md
-            result = wrapped(*args, **kwargs)
+            response = wrapped(*args, **kwargs)
             # TODO: handle streaming
             # if is_streaming(kwargs):
             #     return StreamWrapper(
             #         result, span, event_logger, capture_content
             #     )
 
-            # TODO: add response attributes and events
-            # _set_response_attributes(
-            #     span, result, event_logger, capture_content
-            # )
-            return result
+            if span.is_recording():
+                span.set_attributes(get_genai_response_attributes(response))
+            for event in response_to_events(
+                response=response, capture_content=capture_content
+            ):
+                event_logger.emit(event)
+
+            return response
 
     return traced_method
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py
index 3e6de918f9..36c90d5929 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py
@@ -28,7 +28,10 @@
 
 from opentelemetry._events import Event
 from opentelemetry.instrumentation.vertexai.events import (
+    ChoiceMessage,
+    FinishReason,
     assistant_event,
+    choice_event,
     system_event,
     user_event,
 )
@@ -39,15 +42,25 @@
 from opentelemetry.util.types import AnyValue, AttributeValue
 
 if TYPE_CHECKING:
-    from google.cloud.aiplatform_v1.types import content, tool
+    from google.cloud.aiplatform_v1.types import (
+        content,
+        prediction_service,
+        tool,
+    )
     from google.cloud.aiplatform_v1beta1.types import (
         content as content_v1beta1,
     )
+    from google.cloud.aiplatform_v1beta1.types import (
+        prediction_service as prediction_service_v1beta1,
+    )
     from google.cloud.aiplatform_v1beta1.types import (
         tool as tool_v1beta1,
     )
 
 
+_MODEL = "model"
+
+
 @dataclass(frozen=True)
 class GenerateContentParams:
     model: str
@@ -137,6 +150,24 @@ def get_genai_request_attributes(
     return attributes
 
 
+def get_genai_response_attributes(
+    response: prediction_service.GenerateContentResponse
+    | prediction_service_v1beta1.GenerateContentResponse,
+) -> dict[str, AttributeValue]:
+    finish_reasons: list[str] = [
+        _map_finish_reason(candidate.finish_reason)
+        for candidate in response.candidates
+    ]
+    # TODO: add gen_ai.response.id once available in the python client
+    # https://github.com/open-telemetry/opentelemetry-python-contrib/issues/3246
+    return {
+        GenAIAttributes.GEN_AI_RESPONSE_MODEL: response.model_version,
+        GenAIAttributes.GEN_AI_RESPONSE_FINISH_REASONS: finish_reasons,
+        GenAIAttributes.GEN_AI_USAGE_INPUT_TOKENS: response.usage_metadata.prompt_token_count,
+        GenAIAttributes.GEN_AI_USAGE_OUTPUT_TOKENS: response.usage_metadata.candidates_token_count,
+    }
+
+
 _MODEL_STRIP_RE = re.compile(
     r"^projects/(.*)/locations/(.*)/publishers/google/models/"
 )
@@ -182,7 +213,7 @@ def request_to_events(
 
     for content in params.contents or []:
         # Assistant message
-        if content.role == "model":
+        if content.role == _MODEL:
             request_content = _parts_to_any_value(
                 capture_content=capture_content, parts=content.parts
             )
@@ -196,6 +227,27 @@ def request_to_events(
             yield user_event(role=content.role, content=request_content)
 
 
+def response_to_events(
+    *,
+    response: prediction_service.GenerateContentResponse
+    | prediction_service_v1beta1.GenerateContentResponse,
+    capture_content: bool,
+) -> Iterable[Event]:
+    for candidate in response.candidates:
+        yield choice_event(
+            finish_reason=_map_finish_reason(candidate.finish_reason),
+            index=candidate.index,
+            # default to "model" since Vertex uses that instead of assistant
+            message=ChoiceMessage(
+                role=candidate.content.role or _MODEL,
+                content=_parts_to_any_value(
+                    capture_content=capture_content,
+                    parts=candidate.content.parts,
+                ),
+            ),
+        )
+
+
 def _parts_to_any_value(
     *,
     capture_content: bool,
@@ -208,3 +260,22 @@ def _parts_to_any_value(
         cast("dict[str, AnyValue]", type(part).to_dict(part))  # type: ignore[reportUnknownMemberType]
         for part in parts
     ]
+
+
+def _map_finish_reason(
+    finish_reason: content.Candidate.FinishReason
+    | content_v1beta1.Candidate.FinishReason,
+) -> FinishReason | str:
+    EnumType = type(finish_reason)  # pylint: disable=invalid-name
+    if (
+        finish_reason is EnumType.FINISH_REASON_UNSPECIFIED
+        or finish_reason is EnumType.OTHER
+    ):
+        return "error"
+    if finish_reason is EnumType.STOP:
+        return "stop"
+    if finish_reason is EnumType.MAX_TOKENS:
+        return "length"
+
+    # If there is no 1:1 mapping to an OTel preferred enum value, use the exact vertex reason
+    return finish_reason.name
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/cassettes/test_generate_content_all_input_events.yaml b/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/cassettes/test_generate_content_all_events.yaml
similarity index 100%
rename from instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/cassettes/test_generate_content_all_input_events.yaml
rename to instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/cassettes/test_generate_content_all_events.yaml
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_chat_completions.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_chat_completions.py
index 4a1ab1beba..dc99632263 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_chat_completions.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_chat_completions.py
@@ -38,28 +38,53 @@ def test_generate_content(
     assert dict(spans[0].attributes) == {
         "gen_ai.operation.name": "chat",
         "gen_ai.request.model": "gemini-1.5-flash-002",
+        "gen_ai.response.finish_reasons": ("stop",),
+        "gen_ai.response.model": "gemini-1.5-flash-002",
         "gen_ai.system": "vertex_ai",
+        "gen_ai.usage.input_tokens": 5,
+        "gen_ai.usage.output_tokens": 19,
         "server.address": "us-central1-aiplatform.googleapis.com",
         "server.port": 443,
     }
 
-    # Emits content event
+    # Emits user and choice events
     logs = log_exporter.get_finished_logs()
-    assert len(logs) == 1
-    log_record = logs[0].log_record
+    assert len(logs) == 2
+    user_log, choice_log = [log_data.log_record for log_data in logs]
+
     span_context = spans[0].get_span_context()
-    assert log_record.trace_id == span_context.trace_id
-    assert log_record.span_id == span_context.span_id
-    assert log_record.trace_flags == span_context.trace_flags
-    assert log_record.attributes == {
+    assert user_log.trace_id == span_context.trace_id
+    assert user_log.span_id == span_context.span_id
+    assert user_log.trace_flags == span_context.trace_flags
+    assert user_log.attributes == {
         "gen_ai.system": "vertex_ai",
         "event.name": "gen_ai.user.message",
     }
-    assert log_record.body == {
+    assert user_log.body == {
         "content": [{"text": "Say this is a test"}],
         "role": "user",
     }
 
+    assert choice_log.trace_id == span_context.trace_id
+    assert choice_log.span_id == span_context.span_id
+    assert choice_log.trace_flags == span_context.trace_flags
+    assert choice_log.attributes == {
+        "gen_ai.system": "vertex_ai",
+        "event.name": "gen_ai.choice",
+    }
+    assert choice_log.body == {
+        "finish_reason": "stop",
+        "index": 0,
+        "message": {
+            "content": [
+                {
+                    "text": "Okay, I understand.  I'm ready for your test.  Please proceed.\n"
+                }
+            ],
+            "role": "model",
+        },
+    }
+
 
 @pytest.mark.vcr
 def test_generate_content_without_events(
@@ -81,20 +106,34 @@ def test_generate_content_without_events(
     assert dict(spans[0].attributes) == {
         "gen_ai.operation.name": "chat",
         "gen_ai.request.model": "gemini-1.5-flash-002",
+        "gen_ai.response.finish_reasons": ("stop",),
+        "gen_ai.response.model": "gemini-1.5-flash-002",
         "gen_ai.system": "vertex_ai",
+        "gen_ai.usage.input_tokens": 5,
+        "gen_ai.usage.output_tokens": 19,
         "server.address": "us-central1-aiplatform.googleapis.com",
         "server.port": 443,
     }
 
-    # Emits event without body.content
+    # Emits user and choice event without body.content
     logs = log_exporter.get_finished_logs()
-    assert len(logs) == 1
-    log_record = logs[0].log_record
-    assert log_record.attributes == {
+    assert len(logs) == 2
+    user_log, choice_log = [log_data.log_record for log_data in logs]
+    assert user_log.attributes == {
         "gen_ai.system": "vertex_ai",
         "event.name": "gen_ai.user.message",
     }
-    assert log_record.body == {"role": "user"}
+    assert user_log.body == {"role": "user"}
+
+    assert choice_log.attributes == {
+        "gen_ai.system": "vertex_ai",
+        "event.name": "gen_ai.choice",
+    }
+    assert choice_log.body == {
+        "finish_reason": "stop",
+        "index": 0,
+        "message": {"role": "model"},
+    }
 
 
 @pytest.mark.vcr
@@ -255,7 +294,11 @@ def test_generate_content_extra_params(span_exporter, instrument_no_content):
         "gen_ai.request.stop_sequences": ("\n\n\n",),
         "gen_ai.request.temperature": 0.20000000298023224,
         "gen_ai.request.top_p": 0.949999988079071,
+        "gen_ai.response.finish_reasons": ("length",),
+        "gen_ai.response.model": "gemini-1.5-flash-002",
         "gen_ai.system": "vertex_ai",
+        "gen_ai.usage.input_tokens": 5,
+        "gen_ai.usage.output_tokens": 5,
         "server.address": "us-central1-aiplatform.googleapis.com",
         "server.port": 443,
     }
@@ -274,7 +317,7 @@ def assert_span_error(span: ReadableSpan) -> None:
 
 
 @pytest.mark.vcr
-def test_generate_content_all_input_events(
+def test_generate_content_all_events(
     log_exporter: InMemoryLogExporter,
     instrument_with_content: VertexAIInstrumentor,
 ):
@@ -299,10 +342,10 @@ def test_generate_content_all_input_events(
         ],
     )
 
-    # Emits a system event, 2 users events, and a assistant event
+    # Emits a system event, 2 users events, an assistant event, and the choice (response) event
     logs = log_exporter.get_finished_logs()
-    assert len(logs) == 4
-    system_log, user_log1, assistant_log, user_log2 = [
+    assert len(logs) == 5
+    system_log, user_log1, assistant_log, user_log2, choice_log = [
         log_data.log_record for log_data in logs
     ]
 
@@ -342,3 +385,16 @@ def test_generate_content_all_input_events(
         "content": [{"text": "Address me by name and say this is a test"}],
         "role": "user",
     }
+
+    assert choice_log.attributes == {
+        "gen_ai.system": "vertex_ai",
+        "event.name": "gen_ai.choice",
+    }
+    assert choice_log.body == {
+        "finish_reason": "stop",
+        "index": 0,
+        "message": {
+            "content": [{"text": "OpenTelemetry, this is a test.\n"}],
+            "role": "model",
+        },
+    }
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_utils.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_utils.py
index 082ea72ad9..aeb80a50d2 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_utils.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_utils.py
@@ -13,7 +13,17 @@
 # limitations under the License.
 
 
-from opentelemetry.instrumentation.vertexai.utils import get_server_attributes
+from google.cloud.aiplatform_v1.types import (
+    content,
+)
+from google.cloud.aiplatform_v1beta1.types import (
+    content as content_v1beta1,
+)
+
+from opentelemetry.instrumentation.vertexai.utils import (
+    _map_finish_reason,
+    get_server_attributes,
+)
 
 
 def test_get_server_attributes() -> None:
@@ -30,3 +40,25 @@ def test_get_server_attributes() -> None:
         "server.address": "us-central1-aiplatform.googleapis.com",
         "server.port": 5432,
     }
+
+
+def test_map_finish_reason():
+    for Enum in (
+        content.Candidate.FinishReason,
+        content_v1beta1.Candidate.FinishReason,
+    ):
+        for finish_reason, expect in [
+            # Handled mappings
+            (Enum.FINISH_REASON_UNSPECIFIED, "error"),
+            (Enum.OTHER, "error"),
+            (Enum.STOP, "stop"),
+            (Enum.MAX_TOKENS, "length"),
+            # Preserve vertex enum value
+            (Enum.BLOCKLIST, "BLOCKLIST"),
+            (Enum.MALFORMED_FUNCTION_CALL, "MALFORMED_FUNCTION_CALL"),
+            (Enum.PROHIBITED_CONTENT, "PROHIBITED_CONTENT"),
+            (Enum.RECITATION, "RECITATION"),
+            (Enum.SAFETY, "SAFETY"),
+            (Enum.SPII, "SPII"),
+        ]:
+            assert _map_finish_reason(finish_reason) == expect